Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway by Zhan Y. (4157410)

“…In BV2 cells, LPS treatment decreased expression of BDNF, IL-10, and Arg1, while BDNF overexpression (BDNF-OE) significantly reversed the inflammation-induced by LPS by repressing iNOS and TNF-α, while increasing IL-10 and Arg1. …”

Image 8_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy by Yu Lei (266919)

“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”

Table 1_Nanocarrier-mediated RNAi of CYP9E2 and CYB5R enhance susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx by Farman Ullah (783297)

“…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9E2 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP92 genes. …”

Table 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Supplementary file 1_Effects of human urine application on soil physicochemical properties, microbial communities, and enzymatic activities.docx by Guangquan Yu (21630101)

“…<p>Human urine (HU) is rich in nutrients necessary for plant growth, and recycling HU as fertilizer has multiple positive impacts, such as enhancing agricultural sustainability, reducing wastewater pollution, and decreasing reliance on chemical fertilizers, so it is of great significance to explore the effects of urine agricultural utilization on soil environment. …”

Table 10_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Table 1_Safety and efficacy comparison of single-stage and two-stage ERCP combined with laparoscopic cholecystectomy: a meta-analysis and systematic review.xlsx by Jian-Xiong Tai (22696688)

“…The incidence of pancreatitis was significantly higher in the sequential surgery group compared to LERV (RR = 1.90, 95% CI: 1.61–2.24). …”

Image 3_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Image 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Image 4_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Image 12_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Table 1_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Data from: The relationship between pollinator community and pollination services is mediated by floral abundance in urban landscapes by Hamutahl Cohen (11520447)

“…In the field, we found that jalapeño seed number increased significantly with herbaceous (weed, crop, and ornamental) plant richness and the number of perennial trees and shrubs at the site level, but decreased with the amount of natural landscape cover. …”

Table 3_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Data Sheet 1_Investigating the underlying mechanisms of the ethanol extract of saussureae involucratae herba in anti-rheumatoid arthritis effect based on sphingolipidomics.pdf by Pingyuan Chi (21563069)

“…In cell assays, SIE significantly decreased the protein levels of TNF-α and IL-6 (both P < 0.01) in LPS-stimulated RAW 264.7 cells. …”

Image 10_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Table 2_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Image 11_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”

Image 1_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”