Showing 1,141 - 1,160 results of 21,342 for search '(( significant decrease decrease ) OR ( ((significant rates) OR (significant risks)) decrease ))*', query time: 0.53s Refine Results
  1. 1141

    A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

    Published 2025
    “…<i>In vivo</i> PET/CT imaging and biodistribution analysis revealed that β-branched aromatic α-amino acids modified PSMA radioligands could maintain or even improve tumor targeting while exhibiting a more rapid renal clearance rate than [<sup>68</sup>Ga]Ga-<b>PSMA-617</b>. With average renal uptake of less than 10%ID/g, as opposed to 25%ID/g for [<sup>68</sup>Ga]Ga-<b>PSMA-617</b>, this substantial decrease in renal accumulation translates to a significantly improved safety profile by minimizing nephrotoxic risks. …”
  2. 1142
  3. 1143
  4. 1144
  5. 1145
  6. 1146
  7. 1147
  8. 1148
  9. 1149
  10. 1150
  11. 1151
  12. 1152
  13. 1153
  14. 1154
  15. 1155
  16. 1156
  17. 1157
  18. 1158
  19. 1159
  20. 1160