CMS121 and C75 modulate HSV-1-induced lipogenesis. by Camilla Albano (16446679)

Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isoste... by Mahendiran Dharmasivam (14165426)

“…Considering this: (1) [Fe(PPP4pSe)₂]⁺ demonstrated increased reduction relative to [Fe(PPP4pT)₂]⁺ with glutathione and l-cysteine, while l-ascorbate led to comparable reduction; (2) glutathione led to complete dissociation of [Zn(PPP4pSe)₂], while incomplete dissociation of [Zn(PPP4pT)₂] occurred; and (3) [Cu(PPP4pSe)Cl] demonstrated complete coordinate sphere substitution with glutathione, l-cysteine, and l-ascorbate, whereas [Cu(PPP4pT)Cl] demonstrated partial substitution. The role of glutathione in all three latter reactions is significant, given the greater reactivity of the selenosemicarbazone, and glutathione’s key role in selenosemicarbazone and thiosemicarbazone anticancer activity.…”

Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isoste... by Mahendiran Dharmasivam (14165426)

“…Considering this: (1) [Fe(PPP4pSe)₂]⁺ demonstrated increased reduction relative to [Fe(PPP4pT)₂]⁺ with glutathione and l-cysteine, while l-ascorbate led to comparable reduction; (2) glutathione led to complete dissociation of [Zn(PPP4pSe)₂], while incomplete dissociation of [Zn(PPP4pT)₂] occurred; and (3) [Cu(PPP4pSe)Cl] demonstrated complete coordinate sphere substitution with glutathione, l-cysteine, and l-ascorbate, whereas [Cu(PPP4pT)Cl] demonstrated partial substitution. The role of glutathione in all three latter reactions is significant, given the greater reactivity of the selenosemicarbazone, and glutathione’s key role in selenosemicarbazone and thiosemicarbazone anticancer activity.…”

Raw data. by Camilla Albano (16446679)

“…Blocking CD36 function with SSO further decreased viral infectivity, demonstrating the critical role of lipid uptake in HSV-1 life cycle. …”

HSV-1 infection modulates the fatty acid synthase. by Camilla Albano (16446679)

Estimated variation in <i>R</i> <i>_t</i> (%, and its 95% CI) associated with other driving factors when the mean of serial interval was assumed 2 or 5 days and the end... by Wanqi Wen (20896573)

MTT experiment shows that the seven MUT plasmids of NANOG protein can significantly inhibit the proliferation of colon cancer stem cells. by Yin Tian (181303)

Structure-Affinity-Pharmacokinetics Relationships of Novel ¹⁸F‑Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging by Yui Ishizaka (19922137)

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Constitutive <i>cyc</i> downregulation in <i>Pdf</i>+ cells leads to a reduction in PER levels and arrhythmicity under free-running conditions. by Grace Biondi (19924067)

Negative ion mode significant differential metabolites (Fold Change greater than 2 or less than 0.5). by Peng-fei Han (694841)

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Positive ion mode significant differential metabolites (Fold Change greater than 2 or less than 0.5). by Peng-fei Han (694841)

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Summary schematic of the main statistically significant results of the effects of the three running modalities on the upper limbs compared with the sedentary group. by Andy Xavier (20141395)

NCOA4 protein expression is downregulated and GPX4 protein expression was significantly upregulated in CCA cells. by Wenlong Shen (9313937)

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Statistical Analysis for all Experiments. by Grace Biondi (19924067)

<i>Cyc</i> downregulation in circadian pacemaker neurons prevents the formation of sLN_vs axon bundles. by Grace Biondi (19924067)

Raw data. by Yin Jie (21464235)

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Summary of study participants. by Jesús Poch-Páez (21807825)

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Participants’ characteristics. by Jesús Poch-Páez (21807825)

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Sources of infection. by Jesús Poch-Páez (21807825)

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Clinical characteristics of subjects (N = 37). by Joo-Hoo Park (5702822)

“…<div><p>Th2 inflammation and epithelial-mesenchymal transition (EMT) play crucial roles in the pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP). …”