Table 5_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx by Jiayue Zhang (7832669)

“…Bayesian Age-Period-Cohort (BAPC) modeling was used to predict the incidence rates of different sex and age groups in 2036.</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”

Table 2_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.xlsx by Lauren P. Chrisman (17771613)

“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”

Table 2_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.docx by Fang Peng (327071)

“…Vitamin A deficiency incidence rate decreased by 94.9% (EAPC: −2.02), while DALY rates fell 92.8%. …”

Table_2_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx by Rui Zhu (305217)

“…Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…Subsequently, a series of experiments such as qRT-PCR, Western blot, CCK-8, flow cytometry and ELISA were used to verify the potential mechanism of MFN2.</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Table 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Image 3_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif by Bojun Chen (317487)

“…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…”

Image 8_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg by Jie Li (15030)

“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O₂⁻ production rate. …”

CO₂fertilisation counteracts the negative effect of poor water quality on the growth and photosynthesis of a Great Barrier Reef coralline alga_datasheets by Bonnie Lewis (20407157)

“…We found complex interactions between factors on algal growth and photosynthetic rates, but overall, growth was significantly enhanced by <i>p</i>CO₂ enrichment under all light and nutrient combinations. …”

Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx by Xiaoting Gu (3368495)

“…The gut microbiota composition was analyzed using 16S rRNA sequencing, and metabolic changes were evaluated through untargeted metabolomics of fecal samples.</p>Results<p>Deg-AZM significantly enhanced intestinal motility in the mice with cisplatin-evoked constipation. …”

Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…Bone marrow-derived macrophages and neutrophils were isolated to evaluate GM-CSF’ s impact on chemotaxis, phagocytosis, and killing functions.</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Table 1_Transcriptional patterns of brain structural abnormalities in CSVD-related cognitive impairment.docx by Haixia Mao (3775582)

“…Transcriptome-neuroimaging spatial correlation analysis was carried out in combination with the Allen Human Brain Atlas to explore gene expression profiles associated with changes in cortical morphology in CSVD-related cognitive impairment.</p>Results<p>VBM analysis demonstrated extensive decreased GMV in CSVD-related cognitive impairment in the bilateral temporal lobe and thalamus, especially the hippocampus, thalamus, parahippocampus, and fusiform, and the left temporal lobe showed a more severe atrophy than the right temporal lobe. …”

Table 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Image 3_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg by Ming Lei (161082)

“…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …”

Data Sheet 1_Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microb... by Yunjiao Shen (20524133)

“…High-throughput 16S rRNA sequencing was used to determine the alterations in the gut microbiota.</p>Results<p>In vitro studies demonstrated that TMG significantly inhibited proliferation and promoted apoptosis in CT26.WT cells. …”

Supplementary file 1_Petroselinum sativum (Parsley) extract suppresses oxidative stress and inflammatory responses in human keratinocytes and reduces atopic dermatitis symptoms in... by Juan Wang (115708)

“…Therapeutic efficacy was further evaluated in 2,4-dinitrofluorobenzene (DNFB)-induced AD-like mouse model. The results showed that HE extracts of parsley (HEP) contained the highest TPC and TFC and exhibited the strongest antioxidant activity, significantly improving cell viability and reducing ROS levels in t-BHP-treated cells. …”

Data Sheet 1_Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.docx by Maria Cristina Mauro (22449604)

“…Clinical evaluation was performed at T0 and T1 with validated clinical scales.</p>Results<p>At T0, the SEI in the sensorimotor cluster of the AH was significantly lower than in the UH. …”

Supplementary file 1_Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.xlsx by Linxi Wang (3068649)

“…Additionally, RNA-seq and targeted lipidomics were employed to analyze gene expression and lipid metabolic alterations.</p>Results<p>PAItrap3 significantly reduced blood glucose and glycated hemoglobin levels while improving insulin sensitivity. …”

Image 5_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg by Ming Lei (161082)

“…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …”