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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant change » significant changes (Expand Search), significant challenge (Expand Search), significant challenges (Expand Search)
significant shape » significant gap (Expand Search), significant side (Expand Search), significant short (Expand Search)
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20521
Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20522
Image 2_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif
Published 2025“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”
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20523
Image 2_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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20524
The effect of Tawny crazy ants on the abundance of aboveground insect abundance in Texas
Published 2025“…Additionally, areas were <i>N. fulva </i>were abundant had tended to have fewer grasshoppers from the Melanoplinae subfamily, which are likely decreasing in abundance due to direct predation and fleeing <i>N. fulva</i> abundant areas. …”
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20525
Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc
Published 2025“…Knockdown of PFKFB3 or pharmacological inhibition of glycolysis resulted in decreased insulin secretion and impaired glucose tolerance. …”
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20526
Data Sheet 1_Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway.docx
Published 2025“…In stroke rats, silencing ATF3 reduced brain water content, decreased neurological injury and alleviated cerebral infarction. …”
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20527
Image 1_Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.jpeg
Published 2025“…Moreover, enforced GATA4 re-expression significantly counteracted the toxic effects of ATG5 on DOX-treated hearts. …”
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20528
Table 3_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx
Published 2025“…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …”
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20529
Data Sheet 2_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.docx
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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20530
Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20531
Image 3_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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20532
Table1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.xlsx
Published 2024“…The results show that the COSMO-RS with correction can significantly improve the prediction of CO<sub>2</sub> solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …”
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20533
Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production
Published 2025“…LIF, OCT4, IGF1) were significantly higher in Bio-Block ASCs. Secretome protein declined 35%, 47%, and 10% in 2D, spheroid, and Matrigel, respectively, but was preserved in Bio-Blocks. …”
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20534
Image 10_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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20535
Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx
Published 2025“…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”
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20536
Data Sheet 1_Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials.docx
Published 2025“…Safety analysis revealed that the combination of SSYX and CTs decreased adverse reaction incidence (RR = 0.54, 95% CI 0.32 to 0.90, P = 0.02). …”
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20537
Image 2_Hypomethylation of GCNT2 isoform A correlates with transcriptional expression and is associated with poor survival in acute myeloid leukemia.tif
Published 2025“…DNA methylation of GCNT2 showed a distinctive co-methylation pattern in AML and significantly negatively correlated with transcriptional expression. …”
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20538
Table 1_Hypomethylation of GCNT2 isoform A correlates with transcriptional expression and is associated with poor survival in acute myeloid leukemia.xlsx
Published 2025“…DNA methylation of GCNT2 showed a distinctive co-methylation pattern in AML and significantly negatively correlated with transcriptional expression. …”
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20539
Data Sheet 1_Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models.docx
Published 2025“…At the same time, the levels of these PGs decreased significantly (p < 0.01 vs. LPS-induced group) after the positive drug (dexamethasone) intervention. …”
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20540
Data Sheet 1_Impact of bacteroides uniformis on fatty liver hemorrhagic syndrome in dawu golden phoenix laying hens: modulation of gut microbiota and arachidonic acid metabolism.do...
Published 2025“…The results showed that B. uniformis increased the egg production rate and feed conversion ratio and decreased body weight, liver index, and abdominal fat rate (p < 0.05). …”