Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc... by Yuanhang Rong (19207540)

“…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…”

Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... by Lei Qian (292302)

“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”

Data Sheet 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.docx by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 2_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 5_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 6_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 4_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 3_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

Image 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg by Xinyi Shi (3133611)

“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”

<i>Eggerthella lenta</i> down regulated flavone and flavonol biosynthesis promoted Kawasaki disease by Yao-Tsung Yeh (2009278)

“…Alpha (<i>p</i> < 0.042) and beta (<i>p</i> < 0.001) diversity in KD were significantly decreased when compared to the control group. …”

Data_Sheet_2_Urolithin A alleviates cell senescence by inhibiting ferroptosis and enhances corneal epithelial wound healing.docx by Xiao-Xiao Guo (6092141)

“…The results of RNA-seq of HS-induced corneal epithelial cells showed that the ferroptosis pathway was significantly dysregulated. Further investigation revealed that UA decreased the level of oxidative stress in HCE-T cells, including the levels of LPO and MDA (p < 0.05). …”

Data_Sheet_1_Urolithin A alleviates cell senescence by inhibiting ferroptosis and enhances corneal epithelial wound healing.zip by Xiao-Xiao Guo (6092141)

“…The results of RNA-seq of HS-induced corneal epithelial cells showed that the ferroptosis pathway was significantly dysregulated. Further investigation revealed that UA decreased the level of oxidative stress in HCE-T cells, including the levels of LPO and MDA (p < 0.05). …”

DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx by Rocío Rubio (513839)

“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”

Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif by Jyotsna Mishra (3703195)

“…When both mitochondrial fractions were exposed to increasing mCa²⁺ loads we observed decreased mCa²⁺ sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca²⁺ (ss[Ca²⁺]_e) compared to non-synaptic mitochondria. …”

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... by Yiran Wang (1492303)

“…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I² = 23%) in patients with SGLT-2i treatment compared with non-users. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen... by Zeng Li (688702)

“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”

Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif by Jyotsna Mishra (3703195)

“…When both mitochondrial fractions were exposed to increasing mCa²⁺ loads we observed decreased mCa²⁺ sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca²⁺ (ss[Ca²⁺]_e) compared to non-synaptic mitochondria. …”

S1 File - by Zsófia Tróznai (19923854)

“…Body size, body composition, and maturity had a significant, but of moderate power, effect on the selection. …”

PTEN KD induces EMT in epithelial CRC cells. by Ahmed H. Ghobashi (12705573)

“…All significant comparisons are shown. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.…”