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significant effect » significant impact (Expand Search)
significant time » significant threat (Expand Search), significant gap (Expand Search)
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18621
Supplementary file 2_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx
Published 2025“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”
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18622
Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx
Published 2025“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”
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18623
Table3_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
Published 2024“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”
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18624
<b><i>Assessment of Diseases’ Prevalence, Nutrition and Associated Factors in a Conflict-Affected Region: A Study in Leepa Valley, Azad Jammu and Kashmir, Pakistan</i></b>
Published 2025“…Moreover, 76.3% reported decreased employment opportunities in Leepa Valley due to the ongoing border conflicts. …”
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18625
Table 1_Biofilm formation and role of other pathogenic factors in the virulence of Staphylococcus epidermidis clinical isolates.docx
Published 2025“…<p>Medical device-associated infections represent a significant healthcare challenge, as sterilization of the biomaterial often necessitates device removal. …”
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18626
Table 1_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx
Published 2025“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”
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18627
Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx
Published 2025“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
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18628
Data_Sheet_1_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”
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18629
Image 1_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg
Published 2025“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”
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18630
The statistics of residential land price.
Published 2025“…<div><p>Exploring the spatial structure of residential land prices within metropolitan areas is crucial for identifying regional development disparities. It holds significant practical value for guiding the rational allocation of resources, optimizing land use efficiency, and promoting collaborative development across the metropolitan region. …”
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18631
Table 7_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls...
Published 2025“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”
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18632
Evaluation of Chemical Potentials, Bulk Modulus and Volume Expansion Ratio of Li-Si Alloys with Variety of Li Concentrations Using First-Principles Calculations (Supporting Informa...
Published 2025“…However, in the case of LiSi, which has three different polymorphs, significant variation in the bulk modulus is observed. …”
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18633
Composition and Detailed Characterization of Amino Acids, Peptides, Proteins, Fatty Acids, and Minerals of Tuna Trimming Fish Meal
Published 2025“…Tuna processing byproducts hold significant nutritional value, though their quality can vary based on species, size, environment, and processing level. …”
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18634
A well-resolved phylogeny of <i>Epilobium</i> (Onagraceae) taxa in the British Isles finds no correlation between genomic divergence and the outcome of hybridisation
Published 2025“…<i>Epilobium</i>, contradicting the hypothesis that increasing genetic divergence decreases hybrid formation and hybrid fertility.</p>…”
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18635
Table 4_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls...
Published 2025“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”
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18636
Table 3_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx
Published 2025“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”
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18637
Data_Sheet_4_Global burden of multiple sclerosis and its attributable risk factors, 1990–2019.PDF
Published 2024“…</p>Conclusion<p>Although the global age-standardized DALY rate of MS decreased between 1990 and 2019, MS continues to account for a considerable number of DALYs and prevalent cases. …”
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18638
Composition and Detailed Characterization of Amino Acids, Peptides, Proteins, Fatty Acids, and Minerals of Tuna Trimming Fish Meal
Published 2025“…Tuna processing byproducts hold significant nutritional value, though their quality can vary based on species, size, environment, and processing level. …”
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18639
Data Sheet 1_Left ventricular hypertrophy and myocardial work in amateur marathon runners.pdf
Published 2025“…</p>Conclusion<p>Excessive remodeling leading to LVH may be associated with decreased myocardial work efficiency in amateur marathon runners. …”
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18640
<b>Evaluating Trauma-Focused Cognitive Behavioral Therapy in Earthquake Survivors: A Controlled Trial</b>
Published 2024“…<p dir="ltr">Traumatic events such as earthquakes often lead to significant psychological distress among survivors. …”