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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant effect » significant impact (Expand Search)
significant time » significant threat (Expand Search), significant gap (Expand Search)
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18721
mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t...
Published 2025“…In LSCs, <i>BCL2</i> mRNA level significantly decreased (p = 0.0102) and <i>CDKN1B</i> level significantly increased using 75 µM CoCl<sub>2</sub> treatment. …”
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18722
Data Sheet 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18723
Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf
Published 2025“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”
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18724
DataSheet2_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx
Published 2024“…However, the analysis of paired samples failed to demonstrate a decreasing concentration gradient between the portal and peripheral blood for any of the myokines, evidencing against their release by the primary tumour. …”
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18725
Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl...
Published 2025“…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …”
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18726
Supplementary Material for: Urinary lactate-to-creatinine ratio during the first days of life correlates with the degree of brain damage in premature infants
Published 2024“…Only the GBAS moderate+severe subgroup presented with a secondary increase in the ULCR on the 3rd DOL, whereas in the GBAS normal or mild, the ULCR oscillated around similar values or gradually decreased. Significant positive correlations were detected between the ULCR on the 3rd DOL and the lactate/creatinine and lactate/N-acetyl aspartate ratios measured via 1H-MRS at TEA (r=0.308; p=0.022 and r=0.334; p=0.013, respectively). …”
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18727
Table 1_Remission of obsessive-compulsive disorder using ketogenic metabolic therapy in support of exposure and response prevention: a retrospective case report.docx
Published 2025“…</p>Results<p>Within three weeks of initiating KMT and subsequent ERP, daily compulsive behaviors decreased from 3–8 hours to less than one hour. Significant reductions in DOCS symmetry/ordering subscale scores were sustained at 95 weeks. …”
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18728
Table 2_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.docx
Published 2025“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”
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18729
Data Sheet 1_Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas.pdf
Published 2025“…</p>Results<p>Compared with HCs, dyslipidemic patients showed a significant reduction in gut microbial diversity. Specifically, the abundance of beneficial species—including Faecalibacterium prausnitzii, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium bifidum, and Parabacteroides distasonis—was significantly decreased, while opportunistic pathogens such as Veillonella parvula, V. tobetsuensis, Streptococcus oralis, and Streptococcus mitis were notably enriched. …”
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18730
Renal function and risk of dementia: a Mendelian randomization study
Published 2024“…</p> <p>The findings indicate a significant correlation between each unit increase in cystatin C-based estimated glomerular filtration rate (eGFR-cys) levels was significantly associated with a reduction in the incidence of late-onset Alzheimer’s disease (LOAD) (IVW: OR = 0.35, 95% CI: 0.13–0.91, <i>p</i> = 0.031). …”
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18731
Image 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.jpeg
Published 2025“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”
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18732
Data Sheet 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.zip
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18733
Table 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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18734
Clinical and Imaging Characteristics of Posterior Scleritis in Children
Published 2025“…Retinal nerve fiber layer (RNFL) was thickened in all examined eyes (mean±SD 136.2 ± 28.4 µm) at presentation and it significantly decreased with treatment (109.8 ± 8.2 µm two months later). …”
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18735
Image 1_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.tif
Published 2025“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”
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18736
Image 1_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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18737
Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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18738
Image 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.tif
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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18739
Image 1_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.jpeg
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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18740
Data Sheet 1_Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.pdf
Published 2025“…In the AR + Derp1 group, TSLP was higher, and CCL1 protein levels were decreased. There were no significant differences in IL-25, TGF-β and IL-10. …”