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significant effect » significant impact (Expand Search)
significant time » significant threat (Expand Search), significant gap (Expand Search)
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18801
Table 3_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.docx
Published 2025“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”
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18802
Table 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18803
Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”
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18804
Image 1_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg
Published 2025“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”
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18805
Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur...
Published 2025“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”
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18806
Table 4_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.pdf
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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18807
Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i>
Published 2025“…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …”
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18808
Table 2_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.pdf
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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18809
Table 1_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.doc
Published 2025“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”
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18810
Supplementary file 2_Gut microbiome and serum metabolome alterations in osteosarcoma patients.xlsx
Published 2025“…</p>Results<p>The gut microbial diversity decreased in osteosarcoma patients compared to healthy individuals. …”
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18811
Table 1_The impact of environmental and health messaging, pulse prevalence, and filtering tools on pulse-based food choice and nutrient profiles: a randomized online experiment.doc...
Published 2025“…</p>Discussion<p>Combining messaging with filtering resulted in larger relative increases in pulse choices, suggesting that decreasing product search and identification costs may be an important component of interventions. …”
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18812
Raw Data.
Published 2025“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”
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18813
Image 1_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.png
Published 2025“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”
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18814
Image 2_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg
Published 2025“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”
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18815
Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx
Published 2024“…In the subgroups based on the covariates used in this study, we only identified statistically significant interaction between sex and age. Although ruptured IAs were most common in males and females aged 50–59 and 60–69 years, respectively, risk of IA rupture peaked at ages 30 and 30–50 years in females and males, respectively, and decreased with age in both sexes.…”
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18816
Data Sheet 1_Preoperative geriatric nutritional risk index as a predictor of postoperative delirium in revision arthroplasty: a 10-year retrospective cohort study.docx
Published 2025“…For each 1-unit increase in GNRI, the risk of POD decreased by 4% (OR = 0.96, 95% CI: 0.94–0.99, p = 0.011). …”
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18817
Image 2_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.jpeg
Published 2025“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”
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18818
Table 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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18819
Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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18820
Image 2_Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study.jpeg
Published 2025“…Notably, HS VMAT plans markedly decreased doses to the ipsilateral hippocampus and the contralateral hippocampus, demonstrating its efficacy in hippocampal dose reduction.…”