High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…The differences persisted as follows: reduction of stroke volume in six out of six (6/6) between-quartile comparisons (p<0.001), decrease in cardiac output (p<0.001) and increase in heart rate in 5/6 comparisons (p<0.001), change in systemic vascular resistance in 3/6 comparisons (p<0.001), change in aortic systolic blood pressure in 1/6 comparisons (p=0.043), and change in aortic diastolic blood pressure in none (p=0.266). …”

Data Sheet 1_The impact of small food workshops management regulations on aflatoxin B1 in home-made peanut oil and the liver function of high-consumption area residents: an interru... by Jiangbo Lei (20457626)

“…The implementation of SFWMR was associated with a significant reduction in AFB₁ concentrations in HMPO, showing an immediate decrease of 2.865 μg/kg (P = 0.006) and a sustained annual reduction of 2.593 μg/kg (P = 0.034). …”

Image 1_The role of Sophora alopecuroides alkaloids in colon health of lambs fed high-concentrate diets for extended periods: impact on barrier function, antioxidation, and microfl... by Shufang Li (3183168)

“…The concentration of propionate and lactate in colon contents in HC group increased significantly, while the pH decreased significantly (p < 0.05). …”

Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. by Ana Luisa Dian (22258504)

“…HK2 and SOX10 protein quantification is normalized to VCL expression, and the data presented as relative to high glucose (500 mM). <i><i>p</i></i>-values were calculated by ordinary two-way ANOVA with Dunnett’s multiple comparisons test (SD, <i>n</i> = 3 biological replicates) and only significant comparisons are shown (* <i>p</i> ≤ 0.05, *** <i>p</i> ≤ 0.001). …”

Data Sheet 1_High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry.docx by Takuya Miyamoto (567070)

Video 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.mp4 by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

Scatterplot 1. by Chao Yang (174810)

Table 1_Relationship between high-density lipoprotein cholesterol levels and nutritional risk screening-assessment-intervention: a multicenter cross-sectional study.pdf by Qian Li (114642)

“…In terms of nutritional assessment, patients with constipation, severe infection, chronic kidney disease, fever, high CRP, and hypoalbuminemia significantly increased risks of low HDL-C by 1.432, 2.496, 1.543, 3.056, 1.794, and 2.703 times, respectively. …”

Table 1_Association of high consumption of soy products with the risk of cognitive impairment and major neurocognitive disorders: a systematic review and dose-response meta-analysi... by Jialin Yu (131558)

“…While an association with increased risk of cognitive impairment was observed, it was not statistically significant. The dose-response meta-analysis indicated that a 1-g per day increase in the consumption of soy and natto demonstrated a correlation with an 8 and 14% decrease in the likelihood of developing major neurocognitive disorder, respectively. …”

Image 1_Association of high consumption of soy products with the risk of cognitive impairment and major neurocognitive disorders: a systematic review and dose-response meta-analysi... by Jialin Yu (131558)

“…While an association with increased risk of cognitive impairment was observed, it was not statistically significant. The dose-response meta-analysis indicated that a 1-g per day increase in the consumption of soy and natto demonstrated a correlation with an 8 and 14% decrease in the likelihood of developing major neurocognitive disorder, respectively. …”

Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx by Elisa Barbieri (115023)

Trial design. by Llum Páez (22553360)

“…In summary, the contributions of Neoleish, a vaccine with a very high safety profile, to canine leishmaniasis prevention are: i) The odds-ratio for detectable parasites in blood is 3.5 for vaccinated dogs compared to non-vaccinated dogs; if detected, ~86% lower parasitemia levels are expected; ii) A vaccinated dog has a 2-fold lower risk of developing active infection compared to a non-vaccinated dog; in case positive, the parasite load in bone marrow is expected to be ~96% lower; iii) A 3-fold lower risk (~72.7%) of developing clinical disease is expected in a vaccinated compared to a non-vaccinated dog.…”

Schedule of the trial. by Llum Páez (22553360)

“…In summary, the contributions of Neoleish, a vaccine with a very high safety profile, to canine leishmaniasis prevention are: i) The odds-ratio for detectable parasites in blood is 3.5 for vaccinated dogs compared to non-vaccinated dogs; if detected, ~86% lower parasitemia levels are expected; ii) A vaccinated dog has a 2-fold lower risk of developing active infection compared to a non-vaccinated dog; in case positive, the parasite load in bone marrow is expected to be ~96% lower; iii) A 3-fold lower risk (~72.7%) of developing clinical disease is expected in a vaccinated compared to a non-vaccinated dog.…”

Clinical symptoms scoring system. by Llum Páez (22553360)

“…In summary, the contributions of Neoleish, a vaccine with a very high safety profile, to canine leishmaniasis prevention are: i) The odds-ratio for detectable parasites in blood is 3.5 for vaccinated dogs compared to non-vaccinated dogs; if detected, ~86% lower parasitemia levels are expected; ii) A vaccinated dog has a 2-fold lower risk of developing active infection compared to a non-vaccinated dog; in case positive, the parasite load in bone marrow is expected to be ~96% lower; iii) A 3-fold lower risk (~72.7%) of developing clinical disease is expected in a vaccinated compared to a non-vaccinated dog.…”

Table 1_Immune checkpoint proteins are associated with persistently high liver stiffness after successful HCV treatment in people with HIV: a retrospective study.docx by Rubén Martín-Escolano (17411991)

“…In conclusion, increased plasma concentrations of immune checkpoints one year after successful HCV therapy were linked to persistently high liver stiffness five years later, particularly BTLA, PD-1, and TIM-3. …”

Marketed vaccines against canine leishmaniasis. by Llum Páez (22553360)

“…In summary, the contributions of Neoleish, a vaccine with a very high safety profile, to canine leishmaniasis prevention are: i) The odds-ratio for detectable parasites in blood is 3.5 for vaccinated dogs compared to non-vaccinated dogs; if detected, ~86% lower parasitemia levels are expected; ii) A vaccinated dog has a 2-fold lower risk of developing active infection compared to a non-vaccinated dog; in case positive, the parasite load in bone marrow is expected to be ~96% lower; iii) A 3-fold lower risk (~72.7%) of developing clinical disease is expected in a vaccinated compared to a non-vaccinated dog.…”

Related to Fig 4. <i>NDUFS7</i> depletion in neurons lowers the failure rate of neurotransmission at very low calcium concentrations. by Bhagaban Mallik (12459375)

“…No significant depletion in vesicle pools was observed when <i>UAS-NDUFS7[RNAi]</i>-depleted animals were subjected to high-frequency nerve stimulation for 10 min. …”

Characteristics of the participants. by Kensaku Sasayama (741571)

“…Overall physical activity levels decreased at follow-up compared to baseline. However, the contribution of commuting school activities to overall physical activity significantly increased at follow-up compared to baseline, especially in step counts and MVPA. …”

Inotodiol inhibits HCC cells migration. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol triggered apoptosis in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”