Showing 20,241 - 20,260 results of 21,342 for search '(( significant decrease decrease ) OR ( significance ((b decrease) OR (a decrease)) ))', query time: 0.77s Refine Results
  1. 20241

    Image 1_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

    Published 2025
    “…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
  2. 20242

    Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model by figshare admin karger (2628495)

    Published 2025
    “…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”
  3. 20243

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

    Published 2025
    “…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …”
  4. 20244

    Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

    Published 2025
    “…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
  5. 20245

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  6. 20246

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  7. 20247

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  8. 20248

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  9. 20249

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  10. 20250

    Table1_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).docx by Xiaofei Xu (109890)

    Published 2024
    “…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. Among the detected volatile aromatic substances, the highest-level substance of the fruit was ester, and the ABA treatment significantly promoted the amount of ester substances. …”
  11. 20251

    Effects and Potential Risks of Chiral Penflufen on Pickled Cowpea: Combined Microbiome and Metabolomics by Chao Guo (163795)

    Published 2025
    “…<i>Rac</i>-penflufen treatment significantly decreased the relative abundance of <i>Lactiplantibacillus</i> while increasing <i>Weissella</i>, but the opposite effects were found in <i>R</i>- and <i>S</i>-penflufen treatments. …”
  12. 20252

    Table2_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).xlsx by Xiaofei Xu (109890)

    Published 2024
    “…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. Among the detected volatile aromatic substances, the highest-level substance of the fruit was ester, and the ABA treatment significantly promoted the amount of ester substances. …”
  13. 20253

    Source data.xlsx by Qian Cheng (20991434)

    Published 2025
    “…This limitation restricts electrode thickness, decreases power density, and shortens battery lifetime. …”
  14. 20254

    Figures of manuscript "Fluvoxamine exerts anti-influenza(H1N1) effects through inhibiting apoptosis pathway" by Zhenqiao Wei (22372648)

    Published 2025
    “…This study evaluated the anti-influenza effects of fluvoxamine using H1N1-infected BALB/c mice and found that compared to the H1N1 infection group, the survival rate of mice in the fluvoxamine intervention group increased by 30% (50% <i>vs</i> 20%), with a decreased trend in body weight loss and improved lung tissue lesions. …”
  15. 20255

    DataSheet1_HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab.docx by Toàn Minh Ngô (21195116)

    Published 2025
    “…Purpose<p>Positron emission tomography (PET) hybrid imaging targeting HER2 requires antibodies labelled with longer half-life isotopes. With a suitable radiation profile, <sup>52</sup>Mn coupled with DOTAGA as a bifunctional chelator is a potential candidate. …”
  16. 20256

    Data Sheet 1_Effects of stand structure and soil depth on soil properties in Cryptomeria japonica plantations.xlsx by Laicong Luo (12521938)

    Published 2025
    “…Moreover, soils in stands with good structure exhibited higher organic carbon and total nitrogen contents, particularly in the surface soil layer (0–10 cm), while the C:N, C:P, and N:P ratios gradually decreased with increasing soil depth. The study demonstrated that maintaining a good stand structure—characterized by low canopy closure, high understory vegetation cover, and moderate stand density—can significantly improve soil porosity, water-holding capacity, and nutrient cycling efficiency. …”
  17. 20257

    Data Sheet 1_Silicon (Si) foliar treatment modulates Capsicum annuum L. (green chilli) growth and stress responses under cadmium and lead stress.docx by Waquar Akhtar Ansari (7056191)

    Published 2025
    “…For instance, at 100 mg kg<sup>−1</sup>, Cd and Pb significantly reduced the seed germination (62.5% and 50%), vigor indices (67.2% and 56.8%), root biomass (88% and 66%), chlorophyll a (75.5% and 55.5%) and carotenoids (56.4% and 48.7%) in chilly plants. …”
  18. 20258

    Table 1_Chicory supplementation improves growth performance in juvenile ostriches potentially by attenuating enteritis.xlsx by Meng Li (79487)

    Published 2024
    “…The supplementation of CA at a dose of 80 mg/kg significantly increased the expression level of ZO-1 and claudin-3 (p < 0.0001) and suppressed the levels of IL-1β, IL-6, and TNF-α (p < 0.0001) in ostriches with LPS-induced ileitis.…”
  19. 20259

    Data Sheet 1_Chicory supplementation improves growth performance in juvenile ostriches potentially by attenuating enteritis.docx by Meng Li (79487)

    Published 2024
    “…The supplementation of CA at a dose of 80 mg/kg significantly increased the expression level of ZO-1 and claudin-3 (p < 0.0001) and suppressed the levels of IL-1β, IL-6, and TNF-α (p < 0.0001) in ostriches with LPS-induced ileitis.…”
  20. 20260

    Simultaneous Determination of the Bioavailable Fraction of Eight Elements in Soil Using an Automated Extraction Device and Inductively Coupled Plasma - Optical Emission Spectrometr... by Yigang Ma (22124655)

    Published 2025
    “…Compared with manual methods, the relative standard deviation (RSD) of element detection has been significantly reduced, with values decreasing from 2.01%–23.5% to 1.54%–9.69%. …”