Reliable high-PAP-1-loaded polymeric micelles for cancer therapy: preparation, characterization, and evaluation of anti-tumor efficacy by Fang Ye (112854)

“…These self-assembled micelles exhibited high entrapment efficiency (91.35%) and drug loading level (8.30%). As pH decreased, the micelles exhibited a significant increase in particle size and zeta potential, accompanied by a surge in PAP-1 release. …”

Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

Surface Modification of Islets with L-DOPA-KF7 Enhances Islet Survival by Inhibiting IBMIR in Intrahepatic Islet Transplantation by Daopeng Yang (9701019)

“…Islets coated with L-DOPA-KF7 restored normoglycemia in diabetic mice, and survival time was significantly longer compared to control group. Transplantation of L-DOPA-KF7 coated islets was associated with reduced blood clot formation and decreased infiltration of CD11b+ cells and platelets. …”

Neurochemical identity of dFB^23E10Ո^84C10 neurons. by Joseph D. Jones (13883524)

“…A Kruskal–Wallis ANOVA followed by Dunn’s multiple comparisons revealed that acutely silencing VGlut-AD; 84C10-DBD and 84C10-AD; ChAT-DBD neurons significantly decreases sleep. …”

Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties. by D. Walker Gauthier (21637726)

“…<p><b>(A)</b> Example tuning curves recorded from the inferior colliculus (IC) of a wildtype (left) and <i>Fmr1</i> KO (right) rat. …”

Data Sheet 2_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xlsx by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

CLAD_sequence_files by Ryan Hunter (21714311)

“…<p dir="ltr"><b>Background </b>Progression of chronic lung disease often leads to the requirement for a lung transplant (LT). …”

Data Sheet 1_ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation.pdf by Marco Túlio R. Gomes (5363324)

“…The knockdown of STING by siRNA decreased the residual IFN-β signal elicited by B. abortus infection, demonstrating the presence of a redundant cytosolic DNA-sensing mechanism driving type I IFN production. …”

raw data by Boya Gao (21686150)

“…<p dir="ltr"><b>Introduction and methods: </b>Vegetation disturbance intensity serves as a critical determinant of changes in soil nutrients and microbial communities. …”

Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes. by Zichao Liu (4591993)

“…(e) Significant changes in ion concentrations and reversal potentials occur under prolonged stimulation, following the same trend as shown in (b). …”

Table1_Association mapping for water use efficiency in soybean identifies previously reported and novel loci and permits genomic prediction.xlsx by Siva K. Chamarthi (11130660)

Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP... by Makito Mizunuma (18950775)

“…Percentage of fragmented mitochondria on the <i>y</i>-axis represents the comparison between control and Acetalax-treated groups. <b>A,</b> Significant change in mitochondrial fragmentation is indicated by the brackets. *, <i>P</i> < 0.01; **, <i>P</i> < 0.005; ***, <i>P</i> < 0.0001 (using the Mann–Whitney <i>U</i> test, calculated in Prism 9.0). …”

Table 1_Sijunzi San alleviates the negative energy balance in postpartum dairy cows by regulating rumen fermentation capacity.docx by Feifei Wang (195514)

“…Succiniclasticum and Prevotella showed a significant positive correlation with ruminal SCFAs, whereas UCG-005 exhibited a significant negative correlation with them (p < 0.05). …”

Table 2_Sijunzi San alleviates the negative energy balance in postpartum dairy cows by regulating rumen fermentation capacity.xls by Feifei Wang (195514)

“…Succiniclasticum and Prevotella showed a significant positive correlation with ruminal SCFAs, whereas UCG-005 exhibited a significant negative correlation with them (p < 0.05). …”

Image 1_Sijunzi San alleviates the negative energy balance in postpartum dairy cows by regulating rumen fermentation capacity.jpeg by Feifei Wang (195514)

“…Succiniclasticum and Prevotella showed a significant positive correlation with ruminal SCFAs, whereas UCG-005 exhibited a significant negative correlation with them (p < 0.05). …”

Table 3_Sijunzi San alleviates the negative energy balance in postpartum dairy cows by regulating rumen fermentation capacity.xls by Feifei Wang (195514)

“…Succiniclasticum and Prevotella showed a significant positive correlation with ruminal SCFAs, whereas UCG-005 exhibited a significant negative correlation with them (p < 0.05). …”

Table 1_Analysis of the microstates of prolonged disorders of consciousness.docx by Yuzhang Wu (143824)

“…The Coverage value of MS B (Z = −2.084, p = 0.037), the Occurrence value of MS D (Z = −2.141, p = 0.032), the Coverage value of MS D (Z = −1.999, p = 0.046) between the two groups has a significant difference. …”

Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…<p>PD-1 blockade is minimally effective in AB12 and AE17O mouse mesothelioma tumors before or after TI. <b>A,</b> In subcutaneous AB12 mouse mesothelioma tumors, TI significantly decreased the median tumor growth time to 400 mm³ from 7 days compared with 9 days in untreated TC (<i>P</i> = 0.025). …”