Analysis of cellular proliferation in βA3ΔG91 vs. WT mice lenses using BrdU assay. حسب Akosua K. Boateng (21672931)

Distribution of Differentially Expressed Genes (DEGs) in affected biological pathways in βA3ΔG91 lenses relative to WT lenses. حسب Akosua K. Boateng (21672931)

Protein modeling studies and prediction of amyloidogenic sites in βA3ΔG91 vs. native βA3-crystallin. حسب Akosua K. Boateng (21672931)

Levels of antioxidant enzymes (A) Catalase, (B) Superoxide dismutase, (C) peroxidase. حسب Hammad Ismail (4227988)

Cross-plots of (a) the proposed GPR, Ranjbar-Karaml et al. [14], Christaras et al. [52], Feng et al. [16], Gowida et al. [17] models and (b) Khandelwal et al. [13], Brandås et al.... حسب Fahd Saeed Alakbari (10701871)

Cellular migration in LECs of βA3ΔG91 vs. WT mice using the scratch and transwell assays. حسب Akosua K. Boateng (21672931)

Size-exclusion HPLC and SDS-PAGE Analysis of βA3ΔG91 vs WT mouse lens proteins. حسب Akosua K. Boateng (21672931)

IMU raw data: (a) 3-DoF accelerometer data (b) 3-DoF gyroscope data. حسب Saravanan Manoharan (21273304)

Suture line assessment in lenses of βA3ΔG91 vs. WT mice. حسب Akosua K. Boateng (21672931)

Representative Western blots for proteins from specific gene groups, nitric oxide production, and NETs formation. حسب Daniel R. Ambruso (12042605)

Elevated levels of F-actin in βA3ΔG91 lenses and LECs relative to WT. حسب Akosua K. Boateng (21672931)

Neutrophil function assays completed on CGD patients off and after the 4^th dose of IFN-γ. حسب Daniel R. Ambruso (12042605)

"…<p><b>A. Chemotaxis</b> was measured using transmembrane migration technique in response to buffer, fMLF, PAF, and C5a with concentrations noted. …"

Amyloid staining using Thioflavin. حسب Akosua K. Boateng (21672931)

RNA sequencing analyses of βA3ΔG91 lenses relative to WT lenses. حسب Akosua K. Boateng (21672931)

Mass spectrometric analyses for crystallins. حسب Akosua K. Boateng (21672931)

"…Our results show that relative to WT lenses, the βA3ΔG91 lenses showed: (A) downregulation of genes associated with LECs proliferation and migration (B) abnormal suture line pattern, (C) significant reduction in proliferation and migration of LECs, (D) abnormal F-actin distribution, (E) increased high molecular weight (HMW) peak, and (F) insolubilization and degradation of crystallins and other lens proteins. …"

RNA-seq data showing top 15 downregulated genes. حسب Akosua K. Boateng (21672931)

"…Our results show that relative to WT lenses, the βA3ΔG91 lenses showed: (A) downregulation of genes associated with LECs proliferation and migration (B) abnormal suture line pattern, (C) significant reduction in proliferation and migration of LECs, (D) abnormal F-actin distribution, (E) increased high molecular weight (HMW) peak, and (F) insolubilization and degradation of crystallins and other lens proteins. …"

RNA-seq data showing top 15 upregulated genes. حسب Akosua K. Boateng (21672931)

"…Our results show that relative to WT lenses, the βA3ΔG91 lenses showed: (A) downregulation of genes associated with LECs proliferation and migration (B) abnormal suture line pattern, (C) significant reduction in proliferation and migration of LECs, (D) abnormal F-actin distribution, (E) increased high molecular weight (HMW) peak, and (F) insolubilization and degradation of crystallins and other lens proteins. …"

LDL-C meta-analysis showing in (A) the overall effects of different statin types versus placebo and (B) stratified by statin treatment duration for 3-4 months and longer than 4 mon... حسب Solima Sabeel (9545738)

Neutrophil Superoxide anion production, Heat map for gene expression from neutrophils of CGD patients, and PCA plot for genome-wide gene expression. حسب Daniel R. Ambruso (12042605)

"…Results for healthy adult subjects (black, n = 12) are included for comparison. <b>3B. Heat map</b> showing changes for all significant genes between off IFN-γ and 10-12 hours after the 1st and 4th dose (50 µg/m²) of the cytokine given on a routine schedule noted in Methods. …"

(a) 2D CAD model of tool (b) fabricated tool (c) tool pin geometry. حسب Shaheer Ahmed Khan (17797647)