Image 1_Comprehensive analysis of the prognostic, immunological, and diagnostic roles of SIRT1 in pan-cancer and its validation in KIRC.tif by Qi Liu (33068)

“…SIRT1 expression is significantly correlated with immune regulatory factors across various cancer types. …”

Supplementary file 1_Disentangling the functioning of native soil microbes in enhancing nutritional value of Aloe vera and soil health parameters.docx by Neha Singh Chandel (20944718)

“…Furthermore, bacterial inoculation significantly enhanced soil enzymatic activity and increased the soluble nitrate and phosphate content in the experimental soil. …”

Table 1_CheekAge, a next-generation epigenetic buccal clock, is predictive of mortality in human blood.xlsx by Maxim N. Shokhirev (2391904)

“…To better understand the relative importance of each CheekAge input in blood, we iteratively removed each clock CpG and re-calculated the overall mortality association. The most significant effect came from omitting the CpG cg14386193, which is annotated to the gene ALPK2. …”

Table 8_Integrated genomics, metagenomics and metatranscriptomics to reveal the biocontrol mechanism of Bacillus velezensis JY10 against tobacco target spot disease.xlsx by Wenjuan Yang (174250)

“…Metagenomic profiling showed that JY10 treatment had no significant influence on tobacco phyllosphere and rhizosphere microbiome structure, however, it significantly increased the relative abundance of beneficial microbes, including Bacillus, Pseudonocardia, and Pseudomonas. …”

Table 1_The microbiological and metabolic traits associated with pT3 colorectal cancer metastasis to lymph nodes.xlsx by Lei Chen (54296)

“…We identified 226 differentially expressed genes from TCGA-CRC cohort, among which the upregulated genes were mainly involved in pathways of cancer progression, proliferation, migration, and invasion, while downregulated genes were significantly enriched in pathways of tyrosine metabolism and immunity. …”

Table2_MAPK and phenylpropanoid metabolism pathways involved in regulating the resistance of upland cotton plants to Verticillium dahliae.xls by Mingli Zhang (406266)

“…</p>Results<p>The results revealed a significant differential expression of genes in the two cotton cultivars post V. dahliae infection, with the number of DEGs in JK1775 being higher than that in Z8 at different infection stages of V. dahliae. …”

Supplementary file 3_Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis.xlsx by Yurong Cui (21575129)

“…The expression of NLRP3, Caspase-1, and GSDMD in PEP model was significantly increased compared to the blank group, indicating the activation of NLRP3 inflammasome mediated cell pyroptosis during PEP occurrence. …”

Data Sheet 1_CD44 and CLDN3 as immune-metabolic regulators in acute pancreatitis: a multi-modal transcriptomics study and experimental validation.pdf by Xinwei Wang (352488)

“…Then, single-sample gene set enrichment analysis revealed CLDN3 and CD44 were significantly correlated with immune-related structural remodeling and immune infiltration patterns. …”

DataSheet1_Caffeic acid O-methyltransferase from Ligusticum chuanxiong alleviates drought stress, and improves lignin and melatonin biosynthesis.docx by Enxia Huang (12248422)

“…Under drought conditions, LcCOMT expression was significantly upregulated. Overexpression of LcCOMT gene in Arabidopsis plants conferred enhanced drought tolerance, characterized by elevated lignin and melatonin levels, increased chlorophyll and carotenoid content, heightened activities of antioxidant enzymes peroxidase (POD), catalase (CAT), and superoxide dismutase (SOD), and reduced malondialdehyde (MDA) and hydrogen peroxide (H₂O₂) accumulation. …”

Table 8_The microbiological and metabolic traits associated with pT3 colorectal cancer metastasis to lymph nodes.xlsx by Lei Chen (54296)

“…We identified 226 differentially expressed genes from TCGA-CRC cohort, among which the upregulated genes were mainly involved in pathways of cancer progression, proliferation, migration, and invasion, while downregulated genes were significantly enriched in pathways of tyrosine metabolism and immunity. …”

Supplementary file 4_Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis.docx by Yurong Cui (21575129)

“…The expression of NLRP3, Caspase-1, and GSDMD in PEP model was significantly increased compared to the blank group, indicating the activation of NLRP3 inflammasome mediated cell pyroptosis during PEP occurrence. …”

Image 1_Integrated genomics, metagenomics and metatranscriptomics to reveal the biocontrol mechanism of Bacillus velezensis JY10 against tobacco target spot disease.jpeg by Wenjuan Yang (174250)

“…Metagenomic profiling showed that JY10 treatment had no significant influence on tobacco phyllosphere and rhizosphere microbiome structure, however, it significantly increased the relative abundance of beneficial microbes, including Bacillus, Pseudonocardia, and Pseudomonas. …”

Image1_MAPK and phenylpropanoid metabolism pathways involved in regulating the resistance of upland cotton plants to Verticillium dahliae.tif by Mingli Zhang (406266)

“…</p>Results<p>The results revealed a significant differential expression of genes in the two cotton cultivars post V. dahliae infection, with the number of DEGs in JK1775 being higher than that in Z8 at different infection stages of V. dahliae. …”

DataSheet1_Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data.ZIP by Dmitry Kamashev (11493274)

“…<p>Dual inhibitors of HER2 and EGFR, such as lapatinib, have shown significant efficacy for the therapy of HER2-positive breast cancer. …”

Table 4_Comprehensive proteomic characterization of pulmonary arterial hypertension in Chinese people.xlsx by Tianya Liu (4815150)

“…We analyzed several proteins using PRM, including known candidates such as enolase 1 (ENO1) and chloride intracellular channel 1 (CLIC1), as well as novel proteins such as caveolin-2 (CAV2) and eukaryotic translation initiation factor (EIF2A). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of DEPs showed significant enrichment of biological processes associated with inflammatory response, oxidative stress, and tissue remodeling. …”

Table 6_The microbiological and metabolic traits associated with pT3 colorectal cancer metastasis to lymph nodes.xlsx by Lei Chen (54296)

“…We identified 226 differentially expressed genes from TCGA-CRC cohort, among which the upregulated genes were mainly involved in pathways of cancer progression, proliferation, migration, and invasion, while downregulated genes were significantly enriched in pathways of tyrosine metabolism and immunity. …”

Image 2_CheekAge, a next-generation epigenetic buccal clock, is predictive of mortality in human blood.tif by Maxim N. Shokhirev (2391904)

“…To better understand the relative importance of each CheekAge input in blood, we iteratively removed each clock CpG and re-calculated the overall mortality association. The most significant effect came from omitting the CpG cg14386193, which is annotated to the gene ALPK2. …”

Table 1_Soluble immune checkpoint factors reveal high-risk osteosarcoma subtypes and enable early metastasis prediction.docx by Hanqi Peng (22163200)

“…</p>Results<p>CD48, TIMD-4, B7-H6, CD134, B7-H5, CD47, and S100A8/A9 were significantly elevated in osteosarcoma patients, each linked to increased osteosarcoma risk. …”

Data Sheet 1_Amomum tsaoko flavonoids attenuate ulcerative colitis by inhibiting TLR4/NF-κB/NLRP3 signaling pathway and modulating gut microbiota in mice.docx by Zelin Huang (1935391)

“…Interestingly, these genera were found to be significantly correlated with the UC core phenotypic indicators. …”

Table2_MAPK and phenylpropanoid metabolism pathways involved in regulating the resistance of upland cotton plants to Verticillium dahliae.xls by Mingli Zhang (406266)

“…</p>Results<p>The results revealed a significant differential expression of genes in the two cotton cultivars post V. dahliae infection, with the number of DEGs in JK1775 being higher than that in Z8 at different infection stages of V. dahliae. …”