Image 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.tif حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 3_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 6_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 5_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx حسب Weilin Cui (21758462)

"…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …"

Data Sheet 1_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20... حسب Xin Gong (592328)

"…Disease burden varies significantly across SDI regions, suggesting that preventive measures should be tailored to specific SDI levels.…"

Data Sheet 3_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20... حسب Xin Gong (592328)

"…Disease burden varies significantly across SDI regions, suggesting that preventive measures should be tailored to specific SDI levels.…"

Data Sheet 2_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20... حسب Xin Gong (592328)

"…Disease burden varies significantly across SDI regions, suggesting that preventive measures should be tailored to specific SDI levels.…"

Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx حسب Yewen Sun (8334138)

"…</p>Results<p>It was demonstrated that MFLX induced hyperglycemia in diabetic rats, with a more pronounced reduction in serum insulin, GLP-1, and FGF15 levels than observed in normal rats. Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …"

Presentation 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.zip حسب Xue-Ying Zhang (144147)

"…</p>Results and Discussion<p>Conditional knockdown of hepatic PCSK9 remarkably decreased plasma levels of total cholesterol and alleviated hyperlipidemia-induced liver injury. …"

Data Sheet 1_MgSO4 alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.docx حسب Qiaona Wang (11149563)

"…In CMS-induced mice, MgSO₄ alleviated CMS-induced depressive-like behaviors and hypomagnesemia, reduced the levels of inflammatory cytokines in both serum and hippocampus, decreased the number of Iba⁺ microglia, modulated microglia polarization and repaired the BBB damage. …"

Data Sheet 1_Evaluation of Lactiplantibacillus plantarum CRS 33 to therapeutic effects on a murine model of Escherichia coli-induced endometritis.zip حسب Mingchao Liu (1390666)

"…It also decreased pro-inflammatory cytokine levels and inflammatory cell infiltration, while enhancing microbial diversity and increasing the abundance of beneficial bacterial taxa.…"

Data Sheet 3_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip حسب JunBao Yu (22442218)

"…Concurrently, AFE enhanced antioxidant capacity by increasing glutathione (GSH) levels, decreasing malondialdehyde (MDA), and activating the Nrf2/HO-1 signaling pathway. …"

Data Sheet 1_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip حسب JunBao Yu (22442218)

"…Concurrently, AFE enhanced antioxidant capacity by increasing glutathione (GSH) levels, decreasing malondialdehyde (MDA), and activating the Nrf2/HO-1 signaling pathway. …"

Novel Vanillic Acid-Loaded <i>In Situ</i> Gels: Development, Characterization, <i>In Vitro</i> Evaluation for Enhanced Wound Healing and Skin Irritation Test حسب Gökçe Mutlu Sonat (21726037)

"…Moreover, IN15-VA significantly reduced prostaglandin E2 levels, controlled IL-6 increase and exhibited non-irritating properties. …"

Table 1_Association between body composition in early pregnancy and the risk of gestational diabetes mellitus.docx حسب Yan Li (23143)

"…RCS analysis indicated that the risk of GDM continuously increased with higher levels of PBF and FM, whereas it decreased with FFM and LM (p-overall < 0.001, p-non-linear range: 0.073–0.924). …"

Supplementary file 1_Dynamic changes in peripheral inflammation as a risk factor for perioperative sleep disturbances in elderly patients undergoing laparoscopic hepatobiliary surg... حسب Lai Wei (36699)

"…Findings indicated that elevated NLR and SII levels before and after surgery, alongside decreased plasma IL-10 levels post-surgery, are associated with a higher incidence of PSD. …"

Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip حسب JunBao Yu (22442218)

"…Concurrently, AFE enhanced antioxidant capacity by increasing glutathione (GSH) levels, decreasing malondialdehyde (MDA), and activating the Nrf2/HO-1 signaling pathway. …"

Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx حسب Zhijun Chen (254277)

"…By 12 months, response differences between groups narrowed, and median OS was similar across groups (~22–43 months, p = 0.425). Serum Tg levels declined significantly from baseline in all groups. …"

<b>Enhanced Regulation of Carbon Emissions and DOM Transport by Cascade Reservoirs in the Upper Yellow River</b> حسب Li Chunhui (19796262)

"…The FCH4 in the study area was significantly lower than that of CO2. The vertical distribution of dissolved organic matter (DOM) is depth-dependent: the shallow waters of reservoirs with shallow water depths (≤40 m) had high DOM and humic acid content, humification levels and hydrophobic organic components, whereas the deep waters of reservoirs with deeper water depths (≥70 m) had high DOM and humic acid content, humification levels and hydrophobic organic components. …"