Image2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif by Yifang He (18126257)

“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”

Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m², while it decreased by 11.4ml/min/1.73 m² in the RNU group (WMD, 11.81 ml/min/1.73 m²; 95%CI,9.06-14.56; P<0.0001).…”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study by figshare admin karger (2628495)

“…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …”

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…The results of correlation analysis revealed significant positive correlations (P< 0.05) of forage yield and CP with nutrients efficiency of oat, but negative correlations with fiber content.…”

Data Sheet 4_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 5_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 1_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 3_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 2_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Supplementary file 1_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dep... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Table 8_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 4_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 7_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 10_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 2_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 11_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 1_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 9_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”

Table 5_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

“…Similarly, CD68, CD36, SRB1, and RAGE levels decreased in the frontal cortex. The absence of CX3CR1 significantly altered microglial morphology, resulting in enlarged cell bodies and shortened processes in the hippocampus and frontal cortex. …”