Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf by Shuangmei Zhang (1807303)

“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”

Table 1_Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.docx by Qianyu Bai (21992984)

“…Compared to the DSS group, the SA-Q-CS MPs treatment group showed significant improvements, with the Disease Activity Index (DAI) and histopathological scores reduced by more than 66.9%, pro-inflammatory factor levels decreased by 65%, antioxidant levels increased over sevenfold, and tight junction protein expression elevated by more than threefold. …”

Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx by Naama Lax (20998004)

“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein by Zili Li (20425625)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Table_2_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.XLSX by Yexun Zhou (11711813)

“…We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”

<b>IMPACT OF MULTIVITAMINS AND PROCESSED MEAT ON AGING: A MACHINE LEARNING APPROACH</b> by Mohcene M. (20142864)

“…However, the intake of vitamins significantly attenuated this effect among individuals regardless of their level of processed meat consumption. …”

Table_3_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.DOCX by Yexun Zhou (11711813)

“…We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”

Table 1_Declining trends in sweetness of the diet in the United Kingdom: 2008/9–2018/19.docx by Inga Kutepova (20873687)

“…Overall, the decline in ASE was larger for beverages than foods (ASE values declined 20.7% for beverages vs. 4.4% for foods), although both decreased significantly (p-value < 0.01). Dietary sweetness has changed in the UK, due to a combination of consumer behavior, reformulations, policies, public health awareness programs, and media campaigns, emphasizing its multifactorial nature.…”

Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure by figshare admin karger (2628495)

“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”

Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Table_4_Taxifolin increased semen quality of Duroc boars by improving gut microbes and blood metabolites.DOCX by Yexun Zhou (11711813)

“…We discovered that TAX increased sperm motility significantly in Duroc boars by the elevation of the protein levels such as ZAG, PKA, CatSper, and p-ERK for sperm quality. …”

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models... by Shreshta Jain (12274885)

“…Cognitive function was assessed using the Morris water maze, while brain tissues were examined for oxidative stress markers, autophagy indicators, senescence activity, and amyloid-β levels.</p>Results<p>Decanoic acid significantly improved learning and memory performance, enhanced antioxidant enzyme activity (superoxide dismutase, reduced glutathione, catalase), promoted autophagy by inhibiting mTOR, reduced cellular senescence (β-galactosidase-positive cells), and decreased amyloid-β toxicity. …”

Image 1_Effects of traditional Chinese exercises on post-stroke depression: a meta-analysis of randomized controlled trials.pdf by Yan Li (23143)

“…Specifically, HAMD scores decreased [SMD = −1.40, 95% CI (−1.88, −0.92), p < 0.00001], treatment efficacy improved [OR = 3.74, 95% CI (1.69, 8.28), p = 0.001], FMA scores increased [MD = 6.22, 95% CI (4.12, 8.32), p < 0.00001], and BI levels rose [MD = 4.95, 95% CI (2.96, 6.93), p < 0.00001]. …”

Table 1_Effects of traditional Chinese exercises on post-stroke depression: a meta-analysis of randomized controlled trials.docx by Yan Li (23143)

“…Specifically, HAMD scores decreased [SMD = −1.40, 95% CI (−1.88, −0.92), p < 0.00001], treatment efficacy improved [OR = 3.74, 95% CI (1.69, 8.28), p = 0.001], FMA scores increased [MD = 6.22, 95% CI (4.12, 8.32), p < 0.00001], and BI levels rose [MD = 4.95, 95% CI (2.96, 6.93), p < 0.00001]. …”

Figure 1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action by James P.B. O’Connor (15037863)

“…<b>A,</b> Increased retention of the fluorescent cytotoxic metabolite of banoxantrone, AQ4, as oxygen concentration decreased, with (<b>B</b>) example images shown for cells exposed to 10 µmol/L of banoxantrone differing oxygenation conditions. …”

Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Furthermore, OCT1 protein expression decreased after 1 h and 1 day of HH exposure (P < 0.05), while P-gp expression decreased after 1 h (P < 0.05).…”

Table 1_Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease.docx by Di Zhang (197959)

“…</p>Results<p>The proportion of RUNX2-positive cells in KBD cartilage was significantly higher than in controls. RUNX2 mRNA levels were elevated, whereas methylation levels were reduced in KBD samples. …”

Table 3_Multi-omics analysis reveals the alleviating effect of oxidation remediation on tobacco quinclorac stress.xls by Binghui Zhang (10898910)

“…Metabolomic analysis further confirmed significant changes in metabolite profiles, with K₂S₂O₈ treatment restoring many metabolites to near control levels. …”