DataSheet1_Kidney outcomes associated with SGLT2 inhibitors compared to other glucose-lowering drugs: a real-world study from China.pdf by Xiang Xiao (44417)

“…Throughout the follow-up period, we observed a significant decrease in the rate of eGFR decline in patients using SGLT2i (4.94 mL/min/1.73 m² per year reduction compared to oGLDs, 95% CI: 4.73–5.15). …”

Image4_Kidney outcomes associated with SGLT2 inhibitors compared to other glucose-lowering drugs: a real-world study from China.TIF by Xiang Xiao (44417)

“…Throughout the follow-up period, we observed a significant decrease in the rate of eGFR decline in patients using SGLT2i (4.94 mL/min/1.73 m² per year reduction compared to oGLDs, 95% CI: 4.73–5.15). …”

Image7_Kidney outcomes associated with SGLT2 inhibitors compared to other glucose-lowering drugs: a real-world study from China.TIF by Xiang Xiao (44417)

“…Throughout the follow-up period, we observed a significant decrease in the rate of eGFR decline in patients using SGLT2i (4.94 mL/min/1.73 m² per year reduction compared to oGLDs, 95% CI: 4.73–5.15). …”

Data Sheet 1_Determining the influence of tree age on tea quality-related metabolites in Camellia tachangensis var. remotiserrata by integrating metabolomic and transcriptomic anal... by Zhuorong Shi (22589729)

“…Levels of relatively abundant phenolic acids (e.g., ferulic acid-4-O-glucoside, p-coumaric acid-4-O-glucoside) and flavonoids (e.g., luteolin-3’-O-glucoside, apigenin-4’-O-glucoside) decrease, while catechin content increases significantly, particularly epigallocatechin gallate derivatives. …”

It only gets worse … or does it? The relationship between pain duration and psychological pain factors by Cory Alcon (22551286)

“…There were no differences in pain duration between participants with high versus low levels of pain catastrophizing. For PCS – Magnification, there was a significant difference between the 1–3-year and >10-year groups (<i>p</i> = .012). …”

SERCA is required for Ca²+ transients at E5.5. by Matthew J. Stower (22379321)

“…DMSO treated embryos had a significant decrease in transients (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test; baseline vs. 30 min DMSO <i>p</i> > 0.05), but thapsigargin almost completely abolished transients to a significant effect (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, baseline vs. 30 min 10 nM thapsigargin <i>p</i> ≤ 0.001), that was significantly lower than DMSO controls (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, 30 min DMSO vs. 30 min 10 nM thapsigargin: <i>p</i> ≤ 0.001). …”

<i>In vitro</i> fluorescence imaging and physicochemical characterization of the 3WJ-n × Bro fluorescent aptamer. by Sha Liu (80416)

“…T_m represents the temperature at which fluorescence intensity decreases to 50% of the initial value. Error bars represent mean ± SD (n = 5). …”

Data Sheet 1_Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure.zip by Hui-Ying Liu (10193468)

“…After treatment with S. boulardii (CNCM I-745), the inflammatory damage with sepsis was reduced, and the expression level of occludin was significantly increased. High-throughput sequencing analysis revealed that sepsis injury led to a decline in both the diversity and abundance of the gut microbiota. …”

Table 1_Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii.docx by Qin-Cheng Huang (20944886)

“…A dietary RA level of 296 mg/kg could decrease oxidative stress by upregulating the expression of peroxiredoxin 5 (prx5) and improve immunity by upregulating expression of toll-like receptor 2 (toll2), myeloid differentiation factor 88 (myd88) and dosal in the hepatopancreas. …”

Table 2_Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii.docx by Qin-Cheng Huang (20944886)

“…A dietary RA level of 296 mg/kg could decrease oxidative stress by upregulating the expression of peroxiredoxin 5 (prx5) and improve immunity by upregulating expression of toll-like receptor 2 (toll2), myeloid differentiation factor 88 (myd88) and dosal in the hepatopancreas. …”

Table 1_Secondhand tobacco smoke exposure and sleep disturbance in school-aged children in Appalachian Ohio.docx by Ketrell McWhorter (6339575)

“…Increasing ln serum cotinine levels were associated with a significant 5.5-min decrease in average sleep duration in age-adjusted models.…”

Table 1_Effects of icariin as a feed additive on the reproductive function in bucks (Capra hircus).docx by Fang-e Zhao (20140809)

“…ICA did not affect the body weight of the goats but significantly increased the organ coefficient of the testes (p < 0.01). …”

Data Sheet 1_Effects of icariin as a feed additive on the reproductive function in bucks (Capra hircus).docx by Fang-e Zhao (20140809)

“…ICA did not affect the body weight of the goats but significantly increased the organ coefficient of the testes (p < 0.01). …”

Data Sheet 1_Tobacco- and alcohol-attributable burden of early-onset lip, oral cavity, and pharyngeal cancer in 204 countries and territories from 1990 to 2019, with projections to... by Xingzhu Dai (11086206)

“…</p>Results<p>In 2019, an estimated 16,887 deaths and 799,495 DALYs for tobacco- and alcohol-attributable early-onset LOC, and 8,402 deaths and 386,418 DALYs for early-onset OPC attributable to tobacco and alcohol were reported globally. Despite the global decrease in age-standardized mortality and DALYs rates of tobacco- and alcohol-attributable LOC and OPC in young adults aged 15-49 years between 1990 and 2019, certain regions experienced increases, such as regions of Asia, Eastern Europe, and Western Sub-Saharan Africa. …”

Data Sheet 1_Systematic analysis of the burden of ischemic stroke attributable to high LDL-C from 1990 to 2021.pdf by Jiahao Tang (12360233)

“…</p>Results<p>In 2021, the incidence of ischemic stroke attributed to high LDL-C significantly increased compared to 1990, with a more pronounced growth rate in males. …”

DataSheet1_The harmful effect of ankylosing spondylitis on diabetes mellitus: new evidence from the Mendelian randomization analysis.pdf by Zheng Ren (1766506)

“…</p>Results<p>Our analysis revealed a significant association between AS and an increased risk of T1DM with an odds ratio (OR) of 1.5754 (95% CI: 1.2935 to 1.9187) and T2DM with an OR of 1.0519 (95% CI: 1.0059 to 1.1001). …”

Table 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Table 3_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Image 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.tif by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Supplementary file 1_HuangLian-4 alleviates myocardial ischemia-reperfusion injury by activating the pro-survival STAT3 signaling pathway.doc by Chelimuge Gong (22563287)

“…Mechanistically, our primary finding revealed that HL4 markedly rescued the H/R-induced downregulation of the pro-survival factor STAT3 at both the mRNA and protein levels. This activation of STAT3 was accompanied by a significant increase in the anti-apoptotic protein Bcl-2 and a decrease in pro-apoptotic Bax, alongside the suppression of the maladaptive factor HIF-1α. …”