Image 2_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg حسب Joshua G. Macopson-Jones (20311497)

"…When we examined nuclear export function in SCA7 iPSC-derived cortical neurons, we noted a modest decrease that constituted only a trend. Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…"

The efficacy and safety of Fluticasone Furoate/Umeclidinium/vilanterol (FF/UMEC/VI) on cough symptoms in adult patients with asthma, a randomized double-blind, placebo-controlled,... حسب Etsuko Tagaya (17601425)

"…Furthermore, lung function and adverse events were evaluated.</p> <p>The decrease from baseline in the cough symptom score at week 6 was significantly greater in the FF/UMEC/VI group than in the placebo group (<i>p</i> = 0.006). …"

Table1_Elevational patterns of soil organic carbon and its fractions in tropical seasonal rainforests in karst peak-cluster depression region.docx حسب Bei Zhang (428038)

"…The majority of SOC fractions exhibited an increase with elevation but decrease with soil depth. Notably, only water-soluble organic carbon (WSOC) displayed a decrease with elevation. …"

Image 1_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg حسب Joshua G. Macopson-Jones (20311497)

"…When we examined nuclear export function in SCA7 iPSC-derived cortical neurons, we noted a modest decrease that constituted only a trend. Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…"

Image 3_Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7.jpeg حسب Joshua G. Macopson-Jones (20311497)

"…When we examined nuclear export function in SCA7 iPSC-derived cortical neurons, we noted a modest decrease that constituted only a trend. Furthermore, we identified a significant decrease in the expression of full-length POM121 in SCA7 NPCs.…"

Effect of <i>INS-19</i> and <i>INS-20</i> gene knockout on the growth of <i>Cryptosporidium parvum</i>. حسب Yue Huang (285485)

"…At the peak of infection, mice infected with the <i>Δins-19</i> line showed a threefold decrease in fecal luciferase activity compared to those infected with the IId-GFP line, while those infected with the <i>Δins-20</i> line showed a 6-27-fold decrease in fecal luciferase activity. …"

Table 1_Are alternatively organized value chains more environmentally sustainable? Evidence from soybean production in Minas Gerais and Paraná states, Brazil.docx حسب Réussite Bugale Malembaka (22569818)

"…However, the initial decrease in soybean production volumes might lead to additional land use elsewhere.…"

Table 1_Assessing and projecting the global impacts of Alzheimer’s disease.docx حسب Nanlong Zhang (20563511)

"…</p>Conclusion<p>From 1990 to 2030, global burden of AD is projected to decrease, with significant gender and regional disparities. …"

Data Sheet 1_The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans.... حسب Xiangyu Tan (8639376)

"…There was a significant decrease in the activity of laccase, glucoamylase, and cellulase. …"

Data Sheet 1_Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics.docx حسب Tao Jiang (28401)

"…</p>Results<p>ATM treatment (160 mg/kg) observably ameliorated insulin resistance (IR), hyperglycemia, hyperlipemia and pathological injury in the liver and pancreas. In addition, ATM significantly decreased the expression of TNF-α, IL-1β, IL-6, NF-κB and IL-17A, and significantly increased the level of IL-10 in diabetic mice. 16S rRNA sequencing and targeted GC-MS metabolomics result indicated that ATM restored gut microbiota dysbiosis based on increasing beneficial bacteria Lactobacillus and reducing pathogenic bacteria Helicobacter and Prevotella leading to the accumulation of propionic and valeric acids and the reduction of lipopolysaccharides (LPS) release, intestinal inflammation and intestinal barrier damage. …"

Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization حسب Xiaomin Wu (20328165)

"…The treatment also resulted in a decrease in CD68-positive microglia and reduced expression levels of iNOS and TNF-α, while increasing CD206-positive cells and the expression of Arg-1 and IL-10. …"

Table 1_Effects of litter exposure and flock age of broiler breeders on hatchability and the microbial composition of eggshells, egg membranes, and egg contents.docx حسب Gábor Csitári (21603872)

"…At the phylum level, 16 h of litter exposure significantly increased the abundance of Firmicutes and decreased that of Proteobacteria. …"

Protective effect of polyphenols from Potentilla anserina L. against in rat myocardial ischemia-reperfusion on injury by Wnt/β-catenin pathway حسب Jing Li (10611)

"…Treatment of MIRI with PPA resulted in a significant decrease in protein expression levels of Wnt and β-catenin. …"

S-nitrosoglutathione inhibits pyroptosis of kidney tubular epithelial cells in sepsis via the SIRT3/SOD2/mtROS signaling pathway حسب Heng Fan (814041)

"…However, after SNG pretreatment, the levels of IL-1β, IL-6, IL-18, TNF-α, MDA and mtROS were all significantly decreased, the expression of SIRT3 and SOD2 proteins were increased, NLRP3, GSDMD, Caspase-1 proteins expression and the number of KTECs apoptotic cells were decreased.…"

<b>Nonlifestyle Treatment of Prediabetes</b> حسب Mayer B. Davidson (6175052)

"…Only one showed a statistically significant decrease in diabetes incidence. A more detailed description of the updated guideline follows.…"

Table 3_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx حسب Ruonan Qiang (22753394)

"…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. ASPR and age-standardized YLDs rate demonstrated an initial increase followed by a decrease with rising SDI levels. …"

Table 1_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx حسب Ruonan Qiang (22753394)

"…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. ASPR and age-standardized YLDs rate demonstrated an initial increase followed by a decrease with rising SDI levels. …"

Table 2_Global, regional, and national burden of premenstrual syndrome from 1990 to 2021 and projections to 2050: an analysis based on the 2021 Global Burden of Disease study.xlsx حسب Ruonan Qiang (22753394)

"…Among the five SDI regions, only the high-middle SDI region showed a decrease in burden in 2021 compared to 2019. ASPR and age-standardized YLDs rate demonstrated an initial increase followed by a decrease with rising SDI levels. …"

Table 1_Nutritionally adequate, healthy, and climate-friendly diets following the Nordic Nutrition Recommendations 2023: an optimization study for Norway.xlsx حسب Julie Lengle (21356141)

"…Regardless of degree of environmental impact reduction, diets following NNR2023 guidelines will require significant dietary changes compared to observed intake, including an increase in consumption of fruits, vegetables, and grains, and a strong decrease in consumption of red meat, total meat, and discretionary foods. …"

Image 3_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg حسب Bingtao Hu (16784702)

"…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …"