Image1_RETRACTED: miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats.tif by Yang Yang (45629)

“…A dual-luciferase reporter assay system verified that hsa-miR-16 inhibitory effects involve the targeting of 3′UTR on the 5-HTT gene. Expression levels of miR-16 and BDNF in the hippocampus were examined with RT-PCR, and it was found that increased 5-HT2a receptor expression induced by CUMS can be decreased by miR-16 and Fluoxetine administration. …”

Data Sheet 1_Global, regional, and national trends in ischaemic stroke burden and risk factors among adults aged 20 + years (1990–2021): a systematic analysis of data from the Glob... by Sibo Liu (9975065)

“…The total number of IS cases still increased significantly from 33.2 million to 68.4 million. …”

Effects of berry consumption on cardiometabolic risk factors in patients with metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials by Mohammad Amin Mohammadi (21440815)

“…The subgroup analysis showed that interventions <12 weeks resulted in a significant increase in HDL-C levels and a significant decrease in serum TG levels. …”

The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis by Guowen Zhao (19775328)

“…<p>Gastrointestinal bleeding is an important gastrointestinal complication among peritoneal dialysis patients and correlated with a higher risk of mortality. Increased uric acid levels are a significant complication for peritoneal dialysis patients and have been associated with an increased risk of hemorrhagic stroke. …”

Data Sheet 1_Bacillus coagulans MF-06 alleviates intestinal mucosal barrier from damage in chicks infected with Salmonella pullorum via activating the Wnt/β-catenin pathway.pdf by Li Ma (46633)

“…The study noted a significant decrease in cell apoptosis (p < 0.05) and a significant increase in the expression of Proliferating Cell Nuclear Antigen (PCNA) and v-myc avian myelocytomatosis viral oncogene homolog (C-MYC) (p < 0.05), which activated the Wnt/β-catenin signaling pathway. …”

Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…The signaling pathways regulating the antidepressant properties of OGF were obtained by transcriptome sequencing analysis and validated at the protein level.</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…The signaling pathways regulating the antidepressant properties of OGF were obtained by transcriptome sequencing analysis and validated at the protein level.</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Blood chemistry test results. by Maria A. Colombatti Olivieri (21362615)

“…Red and blue dashed line shows the limit of a significant increase or decrease in the value of the analyte in blood. …”

Table 1_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…A U-shaped relationship was observed between PA and OA risk, with a decrease in OA incidence as PA levels increased, although the protective effect of PA was less pronounced in individuals with severe SB. …”

Table 2_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…A U-shaped relationship was observed between PA and OA risk, with a decrease in OA incidence as PA levels increased, although the protective effect of PA was less pronounced in individuals with severe SB. …”

Image 1_Influence of oropharyngeal therapy with mother’s own milk on the microbiome and metabolome of very preterm infants: a pilot study.pdf by Wenlong Xiu (13251963)

“…Additionally, the OPT-MOM group showed a significant increase in the relative abundance of Streptococcus and Staphylococcus genus, while a significant decrease in Enterococcus and Enterobacter genus abundance was observed in the gut microbiota. …”

Dataset and README file for paper from Denarie et al. by Marie-Emma Denarié (22670696)

“…Si-based defences are rapidly deployed, but it is unclear whether levels of Si defence affect herbivore performance linearly (i.e. increasing levels of Si continue to decrease performance), or whether resistance is only achieved above certain threshold levels.…”

Data Sheet 1_Differential effects of physical activity on behavioral and prefrontal responses during repetitive inhibitory control in older adults.docx by Jae-Hoon Lee (334543)

“…In terms of brain activation, HbO levels increased significantly over time in the left dorsolateral prefrontal cortex and the right ventrolateral prefrontal cortex (p < 0.05), although no significant group differences were observed.…”

Data Sheet 1_Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators.pdf by Michael Hecker (51971)

“…</p>Results<p>The initial therapy with methylprednisolone had no significant effect on immunoglobulin levels and (auto)antibody reactivities (n_max=27 MS patients). …”

Supplementary Material for: Effect of a 48-Hour Thickened Liquid Protocol on Visuospatial Skills in Young Adults by Thompson E. (3351653)

“…Participants in the experimental group reported a decrease in fluid intake. Conclusion: Performance accuracy on a visuospatial task was not significantly impacted by a 48-hour period of thickened liquid intake but time required to complete the task increased and was associated with mild dehydration as indicated by higher USG levels.…”

Supplementary Material for: The effect of LDL receptor–related protein–1 on acute kidney injury and renal tubular epithelial triglyceride accumulation by figshare admin karger (2628495)

“…However, in the in vitro model, although VLDL increased TG levels in HK-2 cells in both normal culture and hypoxia-reoxygenation conditions, it did not alleviate the decrease in cell viability induced by CCCP. …”

Supplementary Material for: Role of melatonin in intestinal mucosal injury induced by chronic restraint stress in mice by figshare admin karger (2628495)

“…Consistent with the decrease in MT levels, we observed a reduction in antioxidant ability and autophagic proteins and increased apoptotic protein levels in the gut, resulting in injury to the intestinal mucosa, which manifested as reductions in the villus height and the V/C ratio; the number of goblets; the number of mast and PCNA-positive cells; and the expression of tight junction proteins (ZO-1, occludin and claudin-1). …”

Data Sheet 1_Safety and immunomodulatory efficacy of heat-killed Mycolicibacterium manresensis as a novel paraprobiotic in swine.pdf by Carmen Álvarez-Delgado (18964264)

“…Piglets supplemented with higher doses of hkMm exhibited a significant increase in salivary adenosine deaminase levels (p = 0.0042), along with a significant decrease in serum haptoglobin concentration (p = 0.0263). …”

Protective effect of polyphenols from Potentilla anserina L. against in rat myocardial ischemia-reperfusion on injury by Wnt/β-catenin pathway by Jing Li (10611)

“…Treatment of MIRI with PPA resulted in a significant decrease in protein expression levels of Wnt and β-catenin. …”

The P-type calcium pump Spf1 regulates immune response by maintenance of the endoplasmic reticulum-plasma membrane contacts during <i>Candida albicans</i> systemic infection by Yuchao Ji (20139542)

“…Immunofluorescence staining and quantitative PCR assays further showed that the <i>SPF1</i> deletion led to a remarkable decrease in the levels of pro-inflammatory cytokines, suggesting the alleviation of the fungus-induced inflammatory response. …”