The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study by Kah Kheng Goh (4983368)

“…Prolactin levels and metabolic parameters were measured at baseline and at weeks 2, 4, 6, and 8.</p> <p>After eight weeks of metformin intervention, prolactin levels significantly decreased from 39.7 ± 20.0 ng/mL at baseline to 35.7 ± 15.7 ng/mL (<i>p</i> = 0.005) with a moderate effect size (Cohen’s <i>d</i> = 0.545). …”

Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf by Keita Tanigaki (13162449)

“…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …”

Table 1_Comparative analysis of soil properties before and after Morchella sextelata cultivation across various soil types.xlsx by Juan Zhao (109151)

“…<p>Morchella, a highly nutritious edible fungus, has been successfully cultivated through artificial means. …”

Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Supplementary file 1_Divergent germination strategies of Phragmites australis seeds for tidal flat gradient adaptation and the implications for coastal wetland restoration.docx by Peng Jia (194819)

“…With the increase in salinity, the germination speeds of different tidal flats slowed down, and the germination index decreased. 4°C storage significantly enhanced the seed germination rate and germination potential of the low-tidal flat population (L) relative to room-temperature storage. …”

Data Sheet 1_Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation.docx by Sarvatit Patel (5558792)

“…<p>Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. …”

Table 1_Comparative study of brain activity and functional connectivity in blepharospasm and blepharospasm-oromandibular dystonia.doc by Yanying Wang (1615096)

“…Comparing with BSP patients, BOM patients showed decreased sFC and dFC strength in a similar but limited pattern. …”

Data Sheet 1_Huoxue-Jiangtang decoction ameliorates type 2 diabetes in high-fat diet and streptozotocin-induced rats.pdf by Maosheng Lee (13041531)

“…Introduction<p>A traditional Chinese herbal decoction, Huoxue-Jiangtang decoction (HXJT), has been clinically prescribed to patients with type 2 diabetes mellitus (T2DM) to improve hyperglycemia and hyperlipidemia for many years. …”

Table 1_Changes in the energy metabolism of the gills of Litopenaeus vannamei under carbonate alkalinity stress and recovery conditions.doc by Meng Xiao (591353)

“…In detail, after CA stress, carbohydrate metabolism related indexes, the pyruvate (PYR) content showed increases, as did the relative expression of the hk, pk, and pdh genes, while the glucose (GLU) and lactate (LAC) content and the expression of the idh gene were slightly decreased; lipid metabolism related indexes, such as the triglycerides (TG) content and the expression of the ampk gene were slightly increased, and the expressions of the srebp, acc, and fas genes were increased significantly; tricarboxylic acid (TCA) cycle related indexes, such as the expressions of the cs, odh, and sdh genes were up-regulated, whereas the expressions of the mdh and idh genes were significantly down-regulated, the expression of the fh gene was slightly decreased in regulation; electron transfer chain related indexes, such as the expressions of the ndh, cytc, coi, cco, and atph genes were significantly increased. …”

Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx by Tianyao Li (7388201)

“…Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects.…”

Table 2_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... by Qi Sun (127)

“…Background<p>Diabetes mellitus (DM) is a chronic metabolic disease, which can not only induce osteoporosis but also accelerate intervertebral disc degeneration (IVDD). …”

Table 1_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... by Qi Sun (127)

“…Background<p>Diabetes mellitus (DM) is a chronic metabolic disease, which can not only induce osteoporosis but also accelerate intervertebral disc degeneration (IVDD). …”

DATA ALL PARTICIPANTS.xlsx by Angela Van Sickle (20441450)

“…For the 5 mL task, time to complete and area under the curve decreased as age increased. Across all ages, males required less time to consume and exhibited significantly less area under the curve when compared to females.…”

Image 2_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.jpeg by Zetong Zheng (22069658)

“…Introduction<p>Several aquaporins (AQPs) are involved in the influx of water to form follicular fluid, and AQP2 may play a crucial role in follicular growth. …”

Image 1_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.tif by Zetong Zheng (22069658)

“…Introduction<p>Several aquaporins (AQPs) are involved in the influx of water to form follicular fluid, and AQP2 may play a crucial role in follicular growth. …”

Table 1_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.docx by Zetong Zheng (22069658)

“…Introduction<p>Several aquaporins (AQPs) are involved in the influx of water to form follicular fluid, and AQP2 may play a crucial role in follicular growth. …”

DataSheet1_Inhibiting glycosphingolipids alleviates cardiac hypertrophy by reducing reactive oxygen species and restoring autophagic homeostasis.pdf by Chunxin Jiang (5212205)

“…Introduction<p>Cardiac hypertrophy is a compensatory stress response produced by a variety of factors, and pathologic hypertrophy can lead to irreversible, severe cardiac disease. …”

Data Sheet 1_Influence of specific tobacco endophytic Bacillus on tobacco leaf quality enhancement during fermentation.pdf by Jinbin Wei (492099)

“…</p>Results<p>Specifically, NS36 decreased offensive taste in tobacco leaves, while NS75 improved the quality by increasing the aroma. …”

Data Sheet 2_Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.pdf by Anita Meinke (14137836)

“…Mean-normalized area between the back and backpack decreased significantly in micro-gravity compared to earth-gravity (p = 0.001), but not during hyper-gravity (p = 1.00). …”