Showing 16,481 - 16,500 results of 17,331 for search '(( significant decrease decrease ) OR ( significance ((p decrease) OR (a decrease)) ))~', query time: 0.68s Refine Results
  1. 16481

    Full name and abbreviation. by Yuanqiang Lv (20623742)

    Published 2025
    “…Treat <i>Gallus gallus</i> exhibiting oxidative stress and immune response caused by aflatoxin b1 with optimal synbiotics for 14 days, detect the changes of inflammatory markers and oxidative stress markers of <i>Gallus gallus</i> using qRT-PCR, and identified the intestinal bacteria genera and their metabolites in the cecum of <i>Gallus gallus</i> using gut microbiota and metabolomics analysis.</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
  2. 16482

    The animal experimental protocol. by Yuanqiang Lv (20623742)

    Published 2025
    “…Treat <i>Gallus gallus</i> exhibiting oxidative stress and immune response caused by aflatoxin b1 with optimal synbiotics for 14 days, detect the changes of inflammatory markers and oxidative stress markers of <i>Gallus gallus</i> using qRT-PCR, and identified the intestinal bacteria genera and their metabolites in the cecum of <i>Gallus gallus</i> using gut microbiota and metabolomics analysis.</p><p>Results and conclusion</p><p>The results indicated that oxidative stress and immune response factor expressions quantity in Gallus gallus decreased significantly after 14 days of treatment, compared with model group, the low-dose treatment group’s SOD1, SOD3, GPX1, GPX2, GSR, H6DP, and HO-1 genes in liver were downregulated by 36.03%, 40.01%, 45.86%, 40.79%, 37.68%, 25.04%, and 29.89%, the IL-1, IL-2, IL-4, IL-6, IgA, IgM, and IgG genes in blood and spleen were downregulated by 26.59%, 34.19%, 21.19%, 28.18%, 35.93%, 12.67%, 21.81 and 35.93%, 22.85%, 21.19%, 28.78%, 35.93%, 15.36%, 29.73%. …”
  3. 16483

    The effect of G83R mutation on transthyretin protein structural stability by Xingwang Chen (11225802)

    Published 2024
    “…<p dir="ltr"><a href="" target="_blank">Transthyretin (TTR</a>) G83R mutation can cause vitreous amyloidosis and severely impair vision. …”
  4. 16484

    Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf by Arjanneke F. van de Merbel (5809940)

    Published 2025
    “…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
  5. 16485

    Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

    Published 2025
    “…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”
  6. 16486

    Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx by Yuqi Liu (501183)

    Published 2025
    “…We established four treatments: control (CK), MI application under normal irrigation (G), drought stress (D), and MI application under drought stress (DG).</p>Results<p>The results demonstrate that MI significantly restored growth parameters under drought conditions, increasing shoot and root biomass by 40.74% and 28.30%, respectively, on Day 7. …”
  7. 16487

    Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc by Wenping Sun (1465360)

    Published 2025
    “…However, its underlying mechanisms remain largely elusive.</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…”
  8. 16488

    Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  9. 16489

    Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg by Shenglan He (7641308)

    Published 2025
    “…</p>Methods<p>In this study, a spontaneous CRC model induced by AOM/DSS was used to evaluate the effects of SB on CAFs. …”
  10. 16490

    Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  11. 16491

    Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx by Lai Yuan (20136422)

    Published 2024
    “…</p>Conclusion<p>This study provides evidence that DBM ameliorates cognitive deficits and depression via improvement of the impairment of synaptic ultrastructure and neuroinflammation, suggesting that DBM is a potential drug candidate for treating AD-related neurodegeneration.…”
  12. 16492

    Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  13. 16493

    Data Sheet 1_Neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; systemic immune-inflammatory Index: inflammatory indicators of cognitive impairment in schizophrenia pati... by Ke Chen (73307)

    Published 2025
    “…Higher NLR, PLR, and SII were substantially related to an increased risk of CI, but higher lymphocytes were associated with a decreased risk of CI.</p>Conclusion<p>NLR, PLR, and SII may be serum inflammatory markers of CI in schizophrenia, and lymphocytes may be protective variables for cognitive function in schizophrenia.…”
  14. 16494

    Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  15. 16495

    SEP-363856 attenuates CUMS-induced depression-like behaviours and reverses hippocampal neuronal injuries by Mengdie Li (7432913)

    Published 2024
    “…<p>This study employed a chronic unpredictable mild stress (CUMS) model to examine the antidepressant properties of SEP-363856.…”
  16. 16496

    Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  17. 16497

    Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

    Published 2025
    “…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
  18. 16498

    Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair by Miaozhong Li (21626739)

    Published 2025
    “…Inflammation, neovascularization, and bone generation were analyzed.</p> <p>The BGC hydrogel scaffold loaded with MSC-EVs maintained bioactivity with excellent biocompatibility and stability, releasing EVs slowly over a month. …”
  19. 16499

    Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx by Shenglan He (7641308)

    Published 2025
    “…</p>Methods<p>In this study, a spontaneous CRC model induced by AOM/DSS was used to evaluate the effects of SB on CAFs. …”
  20. 16500

    Table 1_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Background<p>Premature ventricular contractions (PVCs) are increasingly recognized as a potentially reversible cause of cardiomyopathy, termed PVC-induced cardiomyopathy (PVCCM). …”