Active DNA Demethylation Mediated by <i>OsGADD45a2</i> Regulates Growth, Development, and Blast (Magnaporthe oryzea) Resistance in Rice حسب Ganghua Zhou (9283406)

"…In <i>OsGADD45a2</i> overexpression lines, significant decreases in CG and CHG methylation levels were observed in protein-coding genes, leading to their upregulation. …"

Addressing Imbalanced Classification Problems in Drug Discovery and Development Using Random Forest, Support Vector Machine, AutoGluon-Tabular, and H2O AutoML حسب Ayush Garg (21090944)

"…The important findings of our studies are as follows: (i) there is no effect of threshold optimization on ranking metrics such as AUC and AUPR, but AUC and AUPR get affected by class-weighting and SMOTTomek; (ii) for ML methods RF and SVM, significant percentage improvement up to 375, 33.33, and 450 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy, which are suitable for performance evaluation of imbalanced data sets; (iii) for AutoML libraries AutoGluon-Tabular and H2O AutoML, significant percentage improvement up to 383.33, 37.25, and 533.33 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy; (iv) the general pattern of percentage improvement in balanced accuracy is that the percentage improvement increases when the class ratio is systematically decreased from 0.5 to 0.1; in the case of F1 score and MCC, maximum improvement is achieved at the class ratio of 0.3; (v) for both ML and AutoML with balancing, it is observed that any individual class-balancing technique does not outperform all other methods on a significantly higher number of data sets based on F1 score; (vi) the three external balancing techniques combined outperformed the internal balancing methods of the ML and AutoML; (vii) AutoML tools perform as good as the ML models and in some cases perform even better for handling imbalanced classification when applied with imbalance handling techniques. …"

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses حسب Jing Wang (6206297)

"…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …"

Data. حسب Michael C. Payne (2664379)

"…Using a generalized estimating equation model that accounted for age, sex, bednet use, and sentinel site, we found no significant difference in the effectiveness of the two treatment approaches (p = 0.845 for Mf and p = 0.332 for CFA). …"

Table 1_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 3_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 4_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 8_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 2_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 6_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 5_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 7_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Table 9_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Image 3_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Image 1_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Image 2_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Image 4_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif حسب Stefanie Wagner (743707)

"…Here, GCN correction additionally uncovered significant decreases of Lactobacillus and Faecalibacterium. …"

Probability of Cost-Effectiveness Across CET. حسب Yiping An (20609789)

"…Scenario analyses conducted over a time horizon extending from 10 to 30 years showed that the ICER decreased significantly with longer follow-up, gradually approaching the 0.51GDP threshold and remaining below the 0.90 GDP threshold throughout the analysis.…"

Base-case analysis. حسب Yiping An (20609789)

"…Scenario analyses conducted over a time horizon extending from 10 to 30 years showed that the ICER decreased significantly with longer follow-up, gradually approaching the 0.51GDP threshold and remaining below the 0.90 GDP threshold throughout the analysis.…"

Establishment of a diabetic rat model. حسب Lan Zeng (638254)

"…The abnormal production and release of VEGF promote the proliferation and migration of endothelial cells (ECs), which are critical drivers of retinal neovascularization [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312791#pone.0312791.ref019" target="_blank">19</a>]. Accordingly, we measured VEGF gene expression and found that it was significantly increased in the retinas of diabetic rats (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0312791#pone.0312791.g003" target="_blank">Fig 3A</a>). …"