Expression and diagnostic value of the 8 hub genes in the GSE190635 validation dataset. حسب Wei He (131453)

الموضوعات:

Gene set enrichment analysis (GSEA) of the DEGs. حسب Wei He (131453)

الموضوعات:

ALKL1196M –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Identification of DEGs and DESRGs of AD in the GSE52093 dataset. حسب Wei He (131453)

الموضوعات:

ALK^wt–ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Comparative Analysis of Hela Cells Cultured under Static Conditions and Exposed to Fluid Shear Stress. حسب Xinyao Zhao (5824427)

الموضوعات:

Visualization of immune cell infiltration between AD and control group. حسب Wei He (131453)

الموضوعات:

BCL2 protein keeps their expression in different conditions treatment nevertheless each EML4-ALK cell modells exhibit variable expression. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Combination therapy exhibited apoptosis in Ba/F3 EML4-ALKmutant cell models. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

miR-1247-3p was downregulated in CRC resistant cells. حسب Dequan Wang (6007007)

الموضوعات:

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Downregulation of miR-1247-3p inhibited apoptosis and reduced chemosensitivity in cells. حسب Dequan Wang (6007007)

الموضوعات:

Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

miR-1247-3p was downregulated in tissues of patients with CRC and was associated with prognosis and drug resistance. حسب Dequan Wang (6007007)

الموضوعات:

Causal relationships between allergic diseases and significant declines in lung function: a multivariable Mendelian randomization study حسب Jiannan Lin (6954983)

"…However, in multivariable MR analysis, the independent effects of atopic dermatitis and allergic conjunctivitis on lung function were no longer significant. Only allergic asthma continued to show a significant causal relationship with decreased lung function (OR [95%CI]: 1.019 [1.008–1.030], <i>p</i> < .001).…"

Overexpression of miR-1247-3p promoted apoptosis and inhibited resistance in drug-resistant cells. حسب Dequan Wang (6007007)

الموضوعات:

Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Ba/F3 EML4-ALK^mutants exhibit variable dose-response to ABT-199 treatment. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات: