Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip by Yunsheng Zhang (474242)

“…Background<p>Traumatic brain injury (TBI) triggers a cascade of neuroinflammatory responses mediated by microglial activation, which significantly contributes to secondary brain damage. …”

Data Sheet 1_Effect of Bacillus coagulans BC99 supplementation on body weight and gut microbiota in overweight and obese individual: a randomized, double-blind, placebo-controlled... by Rui Wang (52434)

“…</p>Results<p>After 8 weeks of oral administration, BC99 intervention significantly decreased the body weight of overweight individual (P < 0.01). …”

Data Sheet 1_Plasma testosterone concentration is correlated with circulating immune cell abundance in transgender young people on gender-affirming hormone treatment.pdf by Alice A. White (21695726)

“…<p>Sex hormones, such as oestrogen and testosterone, display significant immune modulatory properties. This is highly relevant for transgender (trans) people who undergo gender-affirming hormone (GAH) treatment. …”

Table 1_Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis.docx by Xuan Wu (126953)

“…Additionally, the percentage of peripheral B cells in the tacrolimus group decreased significantly after treatment (from 11.8 ± 4.7% to 9.4 ± 4.4%, P = 0.006). …”

Data Sheet 1_Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept.docx by Ting Wang (16292)

“…Further, IgM RF and CXCL13 levels decreased only in responders (p=0.02 and 0.004 respectively, at week 24), while anti-CCP levels did not decrease significantly in either responders or nonresponders.…”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…PTA decreased as CrCL increased, with slight variations observed across different PLT levels. …”

Minimal data set. by Zhaoping Meng (4875040)

“…Twenty-two differential metabolites (VIP ≥ 1) were identified using untargeted metabolomics. 3 primary metabolites, namely mannose, pyruvate, and shikimic acid, together with 2 secondary metabolites, phenylalanine and mevalonic acid, were observed to decrease. 17 secondary metabolites, including Schisandrin A, Schisandrin B, Schisandrin C, Gomisin D, Gomisin G, Gomisin H, Benzoylgomisin H, Benzoylgomisin O,Angeloylgomisin P, Catechin, Isorhamnetin, Luteolin, Cinnamic acid, Hydroxycinnamic acid, Hexahydrocurcumin, Coniferyl alcohol, Phenylalanine, Terpinolene and Mevalonic acid, exhibited increases in their levels by 10.64, 1.84, 1.40, 1.64, 4.46, 8.18, 1.72, 10.20, 2.08, 1.27, 1.57, 1.18, 2.01, 1.12, 1.88, 1.15, and 3.17-fold, respectively. …”

(a)Raw soil; (b) The grain size distribution. by Chenhao Li (822769)

Fragmentation patterns for Schisandrin A. by Zhaoping Meng (4875040)

“…Twenty-two differential metabolites (VIP ≥ 1) were identified using untargeted metabolomics. 3 primary metabolites, namely mannose, pyruvate, and shikimic acid, together with 2 secondary metabolites, phenylalanine and mevalonic acid, were observed to decrease. 17 secondary metabolites, including Schisandrin A, Schisandrin B, Schisandrin C, Gomisin D, Gomisin G, Gomisin H, Benzoylgomisin H, Benzoylgomisin O,Angeloylgomisin P, Catechin, Isorhamnetin, Luteolin, Cinnamic acid, Hydroxycinnamic acid, Hexahydrocurcumin, Coniferyl alcohol, Phenylalanine, Terpinolene and Mevalonic acid, exhibited increases in their levels by 10.64, 1.84, 1.40, 1.64, 4.46, 8.18, 1.72, 10.20, 2.08, 1.27, 1.57, 1.18, 2.01, 1.12, 1.88, 1.15, and 3.17-fold, respectively. …”

Chemical structure of a lignan. by Zhaoping Meng (4875040)

“…Twenty-two differential metabolites (VIP ≥ 1) were identified using untargeted metabolomics. 3 primary metabolites, namely mannose, pyruvate, and shikimic acid, together with 2 secondary metabolites, phenylalanine and mevalonic acid, were observed to decrease. 17 secondary metabolites, including Schisandrin A, Schisandrin B, Schisandrin C, Gomisin D, Gomisin G, Gomisin H, Benzoylgomisin H, Benzoylgomisin O,Angeloylgomisin P, Catechin, Isorhamnetin, Luteolin, Cinnamic acid, Hydroxycinnamic acid, Hexahydrocurcumin, Coniferyl alcohol, Phenylalanine, Terpinolene and Mevalonic acid, exhibited increases in their levels by 10.64, 1.84, 1.40, 1.64, 4.46, 8.18, 1.72, 10.20, 2.08, 1.27, 1.57, 1.18, 2.01, 1.12, 1.88, 1.15, and 3.17-fold, respectively. …”

Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx by Chengyu Yang (10223976)

“…Furthermore, SXD extract significantly inhibits hypoxia and senescence pathways in the spleen.…”

Supplementary file 1_A brief mindfulness intervention improves electrophysiological markers of attention in meditation-naïve individuals: the moderating role of inattention symptom... by Xiaoqian Yu (726144)

“…Importantly, inattention symptoms moderated this effect: participants with higher inattention symptoms in the mindfulness group showed a greater increase in P3b amplitude, while those in the control group showed a decrease.…”

Data Sheet 2_A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury.pdf by Yuichi Akama (17892940)

“…We also examine the interaction between Siglec-G and the “don’t-eat-me” signal receptor, CD47. Our data showed that B-1a cell numbers and frequencies in the pleural and peritoneal cavities were significantly decreased in sepsis. …”

Data Sheet 1_A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury.pdf by Yuichi Akama (17892940)

“…We also examine the interaction between Siglec-G and the “don’t-eat-me” signal receptor, CD47. Our data showed that B-1a cell numbers and frequencies in the pleural and peritoneal cavities were significantly decreased in sepsis. …”

Table 3_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 4_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 6_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 2_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 5_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”