Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX حسب György Szklenarik (20296893)

"…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …"

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf حسب Alex Ramos (16267028)

"…ICAM-1, VE-cadherin, and C5b-9 did not differ among groups. ECs incubated with PE-NETs increased VWF and VCAM-1 and decreased VE-cadherin expression vs. control (4 ± 1.6, 5.9 ± 1.2, and 0.5 ± 0.1, respectively, p < 0.05), and notably increased C5b-9 deposit (7.5 ± 2.9, p < 0.05). …"

Reduced expression of MYBPC3 mRNA and cMyBP-C protein in the proband. حسب Yuanyuan Zhang (101797)

"…<p>(A) RT-qPCR analysis showing significantly decreased MYBPC3 mRNA levels in cardiac sample from the proband compared to control subjects. …"

FLEXI interactions with RNA-binding proteins. حسب Jun Yao (9646)

"…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …"

Changes to the host transcriptome during infection. حسب Stefan Bresson (20623940)

"…The heatmap shows the most significantly decreased transcripts (by <i>p</i>-value). …"

Supplementary file 1_Effects of nitrogen addition on SOC in alpine grasslands of the Qinghai-Tibetan Plateau and adjacent mountain regions: a meta-analysis.docx حسب Yanhui Ye (22775894)

"…The soil fungal-to-bacterial ratio (F/B) decreased by 31.0%.</p>Conclusion<p>These results indicate that shifts in microbial community structure drive SOC dynamics in alpine grasslands. …"

Data Sheet 1_Features and rhizosphere colonization strategies of Lactobacillus plantarum 0308 in soil-tomato systems.docx حسب Xiancui Zhang (8349426)

"…Further analyses revealed that LP0308 altered the rhizosphere soil microbial community, significantly increasing the abundance of Bacillus spp. while decreasing the potential pathogenic microorganisms, such as Ralstonia solanacearum and Fusarium oxysporum. …"

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. حسب Aïssatou Aïcha Sow (20371233)

"…Data are shown as means ± SEM. **** P ≤ 0.0001; ns = not significant; one-way ANOVA. (F-G) Total ZIKV RNA (F) and ZIKV negative strand (-) RNA (G) levels in whole larvae pools (6–15 larvae) at 1, 2 and 3 dpf were determined using ddPCR. …"

SLMO is required for the proper function of PISD. حسب Siwen Zhao (543384)

"…At least 10 flies were used, and significant differences were determined using the unpaired <i>t</i> test. …"

Fig. 2 Suppression of miRNA-21-5p ameliorates ovarian pathological alterations, hormonal imbalance, and insulin resistance in PCOS-IR rats. حسب 陈 晓红 (22613498)

"…<p dir="ltr">(A a-d) Hematoxylin and eosin (H&E) staining showed that miRNA-21-5p downregulation improved ovarian morphology in PCOS-IR rats, reducing cystic follicles and restoring granulosa cell layers (scale bar = 250 μm). (B) Silencing miRNA-21-5p significantly lowered serum luteinizing hormone (LH) levels in PCOS rats. …"

PMS repressed ferroptosis in T2DM mice. حسب Hongmin Zhao (20710544)

"…<p>(a,b) TUNEL staining results demonstrated that the number of cell death in the pancreas of T2DM mice was significantly decreased following PMS intervention. …"

Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

"…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…"

Supplementary file 3_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx حسب Xuan Zhao (356028)

"…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …"

Description of the studied population (N = 710). حسب Maryo Baakliny (20910279)

"…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …"

Preventive measures during COVID-19 pandemic. حسب Maryo Baakliny (20910279)

"…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …"

Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... حسب Francisco Alejandro Lagunas-Rangel (13849122)

"…Direct inhibition was observed for two kinases: CAMK1G (IC₅₀ = 8.9 μM) and TSSK1B (IC₅₀ = 3.3 μM). In colorectal cancer cell lines, decreased PI3K phosphorylation was at least partially attributable to mevalonate depletion, a known consequence of statin treatment.…"

Supplementary file 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

"…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…"

Data Sheet 1_Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.pdf حسب J. L. Low (22141795)