يعرض 19,301 - 19,320 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance level decrease ))', وقت الاستعلام: 0.38s تنقيح النتائج
  1. 19301

    Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

    منشور في 2025
    "…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …"
  2. 19302

    Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

    منشور في 2025
    "…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …"
  3. 19303

    Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx حسب Chenyi Shao (6444911)

    منشور في 2025
    "…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …"
  4. 19304

    Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

    منشور في 2025
    "…The data integration of scRNA-seq and bulk RNA-seq showed the decreased TIDE score in the high-risk patients and the elevated levels of Macro-secreted phosphoprotein 1 (SPP1), MDSC-meiotic nuclear divisions 1 (MND1), γδ T cells, and Macro-complement C1q C chain (C1QC) predicted adverse prognosis. …"
  5. 19305

    Presentation 1_Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients.pptx حسب Alain Gelibter (6409364)

    منشور في 2024
    "…Concurrently, 14 soluble immune checkpoints were analyzed by Luminex assay. Immunotherapy significantly increased the levels of Ki67<sup>+</sup>(total and CD8<sup>+</sup>) T cells, PMN(Lox1<sup>+</sup>)-MDSCs, non-suppressive Tregs (nsTregs), and soluble PD1 from T0 to T1 in the entire NSCLC population, while decreased active Tregs. …"
  6. 19306

    Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 حسب Mete Keçeci (20479508)

    منشور في 2024
    "…Cur treatment lowered MDA levels and increased SOD and CAT levels (<i>p</i> < 0.05 for all). …"
  7. 19307

    Table 1_FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis.docx حسب Yu Cheng (136592)

    منشور في 2025
    "…</p>Results<p>FBR2 treatment significantly mitigated BLM-induced lung injury in mice, as evidenced by improved body weight and survival rates, and reduced levels of inflammatory cytokines, including IL-6 and TNF-α. …"
  8. 19308

    Table 2_FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis.xlsx حسب Yu Cheng (136592)

    منشور في 2025
    "…</p>Results<p>FBR2 treatment significantly mitigated BLM-induced lung injury in mice, as evidenced by improved body weight and survival rates, and reduced levels of inflammatory cytokines, including IL-6 and TNF-α. …"
  9. 19309

    Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip حسب Qiwei Zhao (12519351)

    منشور في 2025
    "…Furthermore, CAP increased levels of MDA, Fe²⁺, and ROS while decreasing GSH; these alterations were reversed by Fer-1 treatment. …"
  10. 19310

    Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx حسب Ping-Heng Zhang (21785162)

    منشور في 2025
    "…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …"
  11. 19311

    Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf حسب Mengyuan Dai (9747317)

    منشور في 2025
    "…</p>Results<p>EGCG could reduce reactive oxygen species (ROS) levels and decreased the expression of inflammatory cytokines IL-β, MMP13, and TNF-α. …"
  12. 19312

    DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

    منشور في 2024
    "…Expression analysis revealed that the expression levels of CD163 and CCR1 were significantly down-regulated in HF and NAFLD patients. …"
  13. 19313

    Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome حسب Yokoyama T. (4606381)

    منشور في 2024
    "…Calculated eGFR of adult patients with different HPS types differed significantly, and calculated eGFR of pediatric and adult patients with BLOC-3 disorders was significantly lower than that of patients with BLOC-2 disorders. …"
  14. 19314

    Data Sheet 1_Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.docx حسب Dian-long Li (22465567)

    منشور في 2025
    "…The relative abundance of Proteobacteria in the bacterial community was significantly decreased, while that of Chloroflexi was significantly increased. …"
  15. 19315

    Long-term changes in macronutrients, micronutrients, and potentially toxic elements under 33 years of continuous chemical fertilizer and organic matter application حسب Toan Nguyen-Sy (6333815)

    منشور في 2025
    "…However, micronutrient element levels of Fe, Mn, and Zn decreased, likely due to redox reactions and runoff; meanwhile, potentially toxic elements showed weaker association with organic matter addition and different accumulation patterns in the soil. …"
  16. 19316

    Data Sheet 6_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf حسب Sadia Hamera (22524803)

    منشور في 2025
    "…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
  17. 19317

    Table 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.docx حسب Kexin Xu (757891)

    منشور في 2025
    "…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…"
  18. 19318

    Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

    منشور في 2025
    "…The Italian genotype under the 6:4 photoperiod exhibited the highest concentration of total polyphenols (7.96 mg/g d.w.), including chicoric (3.52 mg/g), rosmarinic (2.79 mg/g), and caffeic acids (0.42 mg/g). Anthocyanin levels in the Rosie genotype also decreased with longer light exposure, with pelargonidin/delphinidin-based pigments dropping from 0.84 mg/g under 6:4 to 0.24 mg/g under 18:6. …"
  19. 19319

    Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

    منشور في 2025
    "…The Italian genotype under the 6:4 photoperiod exhibited the highest concentration of total polyphenols (7.96 mg/g d.w.), including chicoric (3.52 mg/g), rosmarinic (2.79 mg/g), and caffeic acids (0.42 mg/g). Anthocyanin levels in the Rosie genotype also decreased with longer light exposure, with pelargonidin/delphinidin-based pigments dropping from 0.84 mg/g under 6:4 to 0.24 mg/g under 18:6. …"
  20. 19320

    Table 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc حسب Md Shoykot Jahan (22776341)

    منشور في 2025
    "…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…"