<b>Metabolic shifts in ratio of ucOcn to cOcn towards bone resorption contribute to age-dependent bone loss in male mice</b> حسب Bin Wang (16631220)

"…Our findings further demonstrated that the increase in osteoclast activity and the decrease in osteoblast function were significantly corelated with blood levels of ucOcn and cOcn, respectively. …"

Data Sheet 1_An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.pdf حسب Yang Xiao (146335)

"…Mice immunized with LL-plSAM-GILE exhibited significantly elevated levels of specific IgG antibodies. …"

Data Sheet 2_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip حسب Yimin Zhou (3857113)

"…</p>Results<p>Seven CRGs showed differential expression between SCI and non-SCI samples, and there were significant differences in immune cell infiltration levels. …"

Table_1_Regional and social disparities in cessation behavior and motivation to quit among U.S. adult current smokers, Tobacco Use Supplement to the U.S. Census Bureau's Current Po... حسب Candon Johnson (11572623)

"…Notably, the Asian non-Hispanic group in the Northeast experienced a significant decrease in quit interest (–17.9%) but an increase in recent successful cessation (+369.2%).…"

Data Sheet 1_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip حسب Yimin Zhou (3857113)

"…</p>Results<p>Seven CRGs showed differential expression between SCI and non-SCI samples, and there were significant differences in immune cell infiltration levels. …"

<b>Characterizing the role of PP2AB'' family subunits in mechanical stress response and plant development through calcium and ABA signaling in </b><b><i>Arabidopsis thaliana</i></b... حسب Hyuk Sung Yoon (19985262)

"…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb''αβγδ</i> mutant compared to wild type leaves. …"

Table 1_Secondhand tobacco smoke exposure and sleep disturbance in school-aged children in Appalachian Ohio.docx حسب Ketrell McWhorter (6339575)

"…Increasing ln serum cotinine levels were associated with a significant 5.5-min decrease in average sleep duration in age-adjusted models.…"

Data Sheet 1_Acute-phase proteins as biomarkers of inflammation in HIV patients with latent tuberculosis: a prospective study.pdf حسب Nathella Pavan Kumar (8911094)

"…</p>Results<p>Plasma levels of alpha-2-macroglobulin (A2M), C-reactive protein (CRP), serum amyloid P (SAP), haptoglobin, ferritin, soluble transferrin receptor (sTFR), apotransferrin, hepcidin, and S100A8/A9 were assessed using multiplex and quantikine assays.At baseline, levels of A2M, CRP, SAP, ferritin, hepcidin, and S100A9 were significantly elevated in HIV-positive patients with LTBI compared to those without LTBI (A2M, p=0.005; CRP, p<0.001; SAP, p=0.0006; ferritin, p<0.001; hepcidin, p=0.001; S100A9, p=0.001). …"

Data Sheet 1_Systematic analysis of the burden of ischemic stroke attributable to high LDL-C from 1990 to 2021.pdf حسب Jiahao Tang (12360233)

"…Across different SDI regions, trends generally follow a similar downward path, with a narrowing gap in disease burden among regions with varying SDI levels. However, the disease burden in high SDI countries remains significant, indicating potential for reduction. …"

Data from: '<b>From climate warming to accelerated cellular ageing: an experimental study in a wild passerine bird'</b> حسب Antoine Stier (3596369)

"…</i> non-significant decrease in the gene expression of telomerase and protective shelterin). …"

Acteoside inhibits hepatic lipid accumulation and oxidative stress in type 2 diabetic mice via the Nrf2/HO-1 Pathway حسب Dan-Dan Hao (11863637)

"…In diabetes, malondialdehyde (MDA) content was elevated in serum, accompanied by a decrease in superoxide dismutase (SOD) activity. Treatment with acteoside was found to significantly reduce plasma levels TC, TG, LDL, and VLDL accompanied by elevation in HDL, lowered MDA content accompanied by a rise in SOD activity. …"

Table 1_Techno-economic analysis of ocean iron fertilization.docx حسب C. Ward (7771667)

"…Nevertheless, large capital engineering expenditures of approximately $120–160 million also significantly affect the levelized cost. The effect of these high-impact parameters on the LCOC is demonstrated by a cost range from $25 per tonne of CO₂ to $53,000 per tonne of CO₂ for best- to worst-case scenarios when varying values for monitoring, reporting, and verification (MRV) processes, losses due to nutrient robbing, equivalent carbon (CO₂e) losses from N₂O production, CO₂ ventilation losses to the atmosphere, net increase in primary production, and export efficiency are considered. …"

Data Sheet 1_Alteration of vasopressin-aquaporin system in hindlimb unloading mice.zip حسب Marianna Ranieri (330759)

"…Conversely, in 4 weeks HU suspended mice, copeptin decreased significantly and both AQP2 mRNA and AQP2 total protein expression were significantly reduced. …"

Image 1_Alteration of vasopressin-aquaporin system in hindlimb unloading mice.tif حسب Marianna Ranieri (330759)

"…Conversely, in 4 weeks HU suspended mice, copeptin decreased significantly and both AQP2 mRNA and AQP2 total protein expression were significantly reduced. …"

Data Sheet 1_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Data Sheet 1_Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial.pdf حسب Li-qin Meng (20633030)

"…</p>Results<p>Following treatment, FFDS demonstrated significant improvements in serum triglyceride levels (P = 0.013) and a reduction in the frequency of angina episodes (P = 0.021). …"

DataSheet1_The harmful effect of ankylosing spondylitis on diabetes mellitus: new evidence from the Mendelian randomization analysis.pdf حسب Zheng Ren (1766506)

"…Additionally, AS was associated with elevated levels of fasting glucose (beta coefficient = 0.0165, 95% CI: 0.0029 to 0.0301) and blood glucose (beta coefficient = 0.0280, 95% CI: 0.0086 to 0.0474), alongside a decrease in fasting insulin levels (beta coefficient = -0.0190, 95% CI: -0.0330 to -0.0050).…"

Data Sheet 3_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Table 3_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.docx حسب Ru Chen (186859)

"…Regionally, both mortality rates and DALYs significantly decrease with increasing SDI. Sub-Saharan Africa and South Asia have high levels of incidence and prevalence. …"