Presentation 1_Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV.pptx حسب Matteo Vassallo (10293461)

"…Among PLWH, adjusting for age, gender, HIV follow-up and duration on ART, those with a CD4/CD8 ratio < 0.76 had more senescent CD8+ cells (AdjOR = 0.93, 95%CI = [0.88; 0.97], p-value = 0.003). Higher levels of CD8+ senescence persisted for lower CD4/CD8 ratios, with, in addition, a significant decrease in NK cells in case of a ratio < 0.4. …"

Table 2_Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV.xlsx حسب Matteo Vassallo (10293461)

"…Among PLWH, adjusting for age, gender, HIV follow-up and duration on ART, those with a CD4/CD8 ratio < 0.76 had more senescent CD8+ cells (AdjOR = 0.93, 95%CI = [0.88; 0.97], p-value = 0.003). Higher levels of CD8+ senescence persisted for lower CD4/CD8 ratios, with, in addition, a significant decrease in NK cells in case of a ratio < 0.4. …"

Table 1_Correlation between CBC-derived inflammatory indicators and all-cause mortality with rheumatoid arthritis: a population-based study.docx حسب Yu Liu (6938)

"…The Kaplan-Meier analysis indicated a significant decrease in the survival probability among individuals with elevated SIRI, NLR, and MLR levels. …"

Sex hormone stimulation of CRISPR-modified HepG2 cells alters alpha-1 antitrypsin production حسب Emma Leacy (11872358)

"…</p><p dir="ltr"><b>Results:</b> Both hormones significantly reduced intracellular AAT (Figure 1A), even at low concentrations. …"

Image 1_Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway.tif حسب Lu Liu (171341)

"…Mechanistic studies revealed that EPE promoted IFN-β release in NK cells, significantly increased the phosphorylation levels of STING and IRF3. …"

Data Sheet 1_Spatiotemporal analysis of the burden of lower respiratory infections in the older adult population due to air pollution: trends from 1990 to 2021 and predictions for... حسب Zheng Lei (2250328)

"…Background<p>Lower respiratory infections (LRI), caused by various pathogens, have significant impacts on global health. Air pollution is a major environmental factor in the development of LRI, and with ongoing urbanization and industrialization, it has become a critical public health concern. …"

Data Sheet 1_Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast.pdf حسب Constanza Ricaurte-Villota (14169471)

"…The observed trends in pH and pCO₂ were driven by a decrease in DIC and TA, attributed to increased river runoff, contrasting with typical ocean acidification trends driven by rising atmospheric CO₂ levels.…"

Table 1_Anti-heat stress lick block supplementation alleviated the detrimental effects of heat stress on dairy cows.docx حسب Hongwei Duan (1279806)

"…</p>Results<p>Heat stress levels varied from severe (THI > 88) to moderate heat stress (THI > 80) in the first 2 weeks, gradually decreasing to mild heat stress (THI > 72) in the following weeks. …"

Table 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.docx حسب Chengzhi Hou (20419865)

"…</p>Results<p>A total of 2,045 MACCE survivors were included. The higher levels of ALI and serum albumin were significantly associated with lower risks of all-cause and cardiovascular mortality among these individuals. …"

DataSheet1_Enhancing human islet xenotransplant survival and function in diabetic immunocompetent mice through LRH-1/NR5A2 pharmacological activation.pdf حسب N. Cobo-Vuilleumier (14625173)

"…Accordingly, in mice treated with BL001 for 8 weeks, the beta cell mass was preserved, while a significant decrease in alpha cells was observed compared to mice treated with BL001 for only 4 weeks. …"

Supplementary Material for: Effects of a Sugar-Sweetened Beverages Tax on Caries in Italy: a Modelling Study. حسب figshare admin karger (2628495)

"…Introduction: Despite efforts to reduce sugar consumption, Italy continues to experience high levels of caries, particularly among 12-year-old children. …"

Image 1_Inflammation and nutritional status in relation to mortality risk from cardio-cerebrovascular events: evidence from NHANES.tif حسب Chengzhi Hou (20419865)

"…</p>Results<p>A total of 2,045 MACCE survivors were included. The higher levels of ALI and serum albumin were significantly associated with lower risks of all-cause and cardiovascular mortality among these individuals. …"

Data Sheet 2_Toxocariasis in children: seroprevalence after 15 years in a major city in Brazil.docx حسب Viviane dos Santos Vaccaro Lima (22644209)

"…In conclusion, although toxocariasis in children may not increase over time, such seroprevalence may not decrease either, persisting (even in low levels) for long periods.…"

Data Sheet 1_CD8+ T cells mediate the impact of gut dysbiosis and short-chain fatty acid deficiency on accelerated arthritis progression in collagen-induced arthritis mice.docx حسب Xiangcong Zhao (12573181)

"…The gut microbiota exhibited reduced α-diversity, enriched Bacteroidetes, depleted Firmicutes, and decreased Lachnospiraceae_NK4A136_group. Fecal SCFA levels declined, while the proportion of IgA-coated bacteria increased. …"

Data Sheet 1_Toxocariasis in children: seroprevalence after 15 years in a major city in Brazil.pdf حسب Viviane dos Santos Vaccaro Lima (22644209)

"…In conclusion, although toxocariasis in children may not increase over time, such seroprevalence may not decrease either, persisting (even in low levels) for long periods.…"

Table 1_Associations between the Dietary Inflammatory Index and depression among pregnant and postpartum women: analysis of NHANES 2005–2018.docx حسب Jian Qiao (26659)

"…Diets with very high proinflammatory potential were linked to significantly increased odds of perinatal depression, whereas more anti-inflammatory diets did not result in a further decrease in depression risk below that threshold. …"

Image_2_Abnormal outer and inner retina in a mouse model of Huntington’s disease with age.JPEG حسب Dashuang Yang (19956078)

"…Structurally, R6/1 mice demonstrated a global reduction in cone opsin expression as early as 2 months, with a decrease in rhodopsin levels at 4 months, alongside a thinner retinal structure compared to controls. …"

Table 6_Global burden of low back pain attributable to smoking in 204 countries and territories in 1990–2021.xlsx حسب Baodong Wang (3359171)

"…However, the effect of smoking on the burden of LBP has not been thoroughly examined at the global, regional, and national levels. This study aims to analyze the trends in smoking-related LBP from 1990 to 2021. …"

Image_1_Abnormal outer and inner retina in a mouse model of Huntington’s disease with age.JPEG حسب Dashuang Yang (19956078)

"…Structurally, R6/1 mice demonstrated a global reduction in cone opsin expression as early as 2 months, with a decrease in rhodopsin levels at 4 months, alongside a thinner retinal structure compared to controls. …"

Image_3_Abnormal outer and inner retina in a mouse model of Huntington’s disease with age.JPEG حسب Dashuang Yang (19956078)

"…Structurally, R6/1 mice demonstrated a global reduction in cone opsin expression as early as 2 months, with a decrease in rhodopsin levels at 4 months, alongside a thinner retinal structure compared to controls. …"