يعرض 7,401 - 7,420 نتائج من 8,285 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance level decrease ))~', وقت الاستعلام: 0.44s تنقيح النتائج
  1. 7401

    Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio... حسب Liming Liu (107470)

    منشور في 2025
    "…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …"
  2. 7402

    Measurement of interference efficiency of AjNLRC4 or AjCASP-1 by specific siRNA transfection. حسب Kaiyu Chen (11691918)

    منشور في 2025
    "…It was found that after the above treatment, the mRNA and protein levels of AjNLRC4 were significantly decreased. Results are representative of at least three independent experiments, and error bars denote the SD of triplicate wells. …"
  3. 7403

    Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx حسب Tianyao Li (7388201)

    منشور في 2025
    "…Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects.…"
  4. 7404

    Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx حسب Demet Kartal (20817926)

    منشور في 2025
    "…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …"
  5. 7405

    Table 1_Gut microbiota alterations and systemic inflammation in community-acquired pneumonia: a prospective gut-lung axis study.docx حسب Xue-Qin Yang (3494345)

    منشور في 2025
    "…Serum detection revealed that the levels of lipopolysaccharide (LPS), TNF-α, and IL-6 were significantly increased in CAP patients. …"
  6. 7406

    <b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b> حسب XIN CHEN (10031207)

    منشور في 2025
    "…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …"
  7. 7407

    <b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>Item حسب XIN CHEN (10031207)

    منشور في 2025
    "…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …"
  8. 7408

    Data Sheet 1_Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection.pdf حسب Estíbaliz Alegría-Carrasco (22809476)

    منشور في 2025
    "…</p>Results<p>TLR7 levels were higher in patients with mild disease compared to those with moderate disease and decreased over time. …"
  9. 7409

    Cholecalciferol alleviates testicular dysfunction in experimental hyperthyroidism via antioxidant, anti-inflammatory and antiapoptotic effects حسب Heba Rady Salem (21356361)

    منشور في 2025
    "…It significantly decreased the levels of serum inflammatory markers and malondialdehyde levels. …"
  10. 7410

    Table_1_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

    منشور في 2024
    "…Metabolome results further revealed that the serum alanine levels in AECOPD patients were significantly lower than those in COPD patients, and these differential metabolites were mainly involved in linoleic acid metabolism, protein digestion and absorption and regulation of lipolysis in adipocytes. …"
  11. 7411

    Table_3_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

    منشور في 2024
    "…Metabolome results further revealed that the serum alanine levels in AECOPD patients were significantly lower than those in COPD patients, and these differential metabolites were mainly involved in linoleic acid metabolism, protein digestion and absorption and regulation of lipolysis in adipocytes. …"
  12. 7412

    Table_2_Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.pdf حسب Yanmin Shi (16516917)

    منشور في 2024
    "…Metabolome results further revealed that the serum alanine levels in AECOPD patients were significantly lower than those in COPD patients, and these differential metabolites were mainly involved in linoleic acid metabolism, protein digestion and absorption and regulation of lipolysis in adipocytes. …"
  13. 7413

    Supplementary file 1_Clinical application of combined anticoagulation therapy in anti-MDA5 antibody-positive associated interstitial lung disease-a retrospective study.docx حسب Ting Zhang (102583)

    منشور في 2025
    "…</p>Results<p>At 4-week treatment and 3-month follow-up, the combined anticoagulation group had superior Forced Vital Capacity (FVC)%, Diffusing Capacity of the Lung for Carbon Monoxide (DLCO)%, and Arterial Partial Pressure of Oxygen (PaO<sub>2</sub>) levels compared to the control group (P < 0.05). Meanwhile, C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine Kinase (CK) levels decreased significantly. …"
  14. 7414

    Table5_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  15. 7415

    Table4_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  16. 7416

    Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  17. 7417

    Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  18. 7418

    Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  19. 7419

    Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …"
  20. 7420

    Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf حسب Dan Li (106345)

    منشور في 2025
    "…</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …"