بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
level decrease » levels decreased (توسيع البحث), level increased (توسيع البحث), teer decrease (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
level decrease » levels decreased (توسيع البحث), level increased (توسيع البحث), teer decrease (توسيع البحث)
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7961
Image 2_13C-CO2 pulse labelling evaluation of water deficit on leaf carbon dynamics and whole plant allocation in fruiting coffee.png
منشور في 2025"…These were analysed to assess <sup>13</sup>C enrichment in relation to carbon assimilation and leaf carbon changes over time. Water deficit significantly decreased carbon assimilation by 20-52% compared to well-watered plants, especially in young leaves (p< 0.05). …"
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7962
Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
منشور في 2025"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
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7963
Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
منشور في 2025"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
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7964
Data Sheet 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf
منشور في 2025"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"
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7965
Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
منشور في 2025"…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …"
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7966
Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat...
منشور في 2025"…After 28 days of intervention, the lower and higher doses of the bioactive fraction (100 and 200 mg/kg BW) substantially decreased fasting blood glucose levels and ameliorated hyperglycemia, glucose intolerance, insulin resistance, and hyperlipidemia. …"
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7967
Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx
منشور في 2025"…To mimic neuroinflammatory conditions, HMC3 cells were stimulated with interferon-gamma (IFN-γ), which significantly increased intracellular ROS levels, surface expression of CD40 and CD86, and secretion of pro-inflammatory cytokines. …"
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7968
Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
منشور في 2025"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
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7969
Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif
منشور في 2025"…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …"
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7970
Presentation 1_Ischemia-reperfusion injury with a model of porcine whole-blood ex-vivo lung perfusion.pptx
منشور في 2025"…Interleukin-6 and −8 levels after 6 h were significantly higher in the long CIT group (mean differences, 1.1 pg/ml; 95% CI, 0.39–1.8; P = 0.003; and 29.31 pg/ml; 95%CI, 16.00–42.61; P < 0.001; respectively). …"
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7971
Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
منشور في 2025"…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …"
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7972
Image 1_Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.jpeg
منشور في 2025"…Moreover, enforced GATA4 re-expression significantly counteracted the toxic effects of ATG5 on DOX-treated hearts. …"
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7973
Table 3_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx
منشور في 2025"…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …"
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7974
Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx
منشور في 2025"…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …"
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7975
Image 4_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg
منشور في 2024"…An area under the curve analysis using a random forest model based on fecal metagenomics, plasma metabolomics, and tissue metabolomics revealed that gut bacteria, plasma, and tissue metabolites were effective in distinguishing between MK and NS groups. Decreased Bacteroides plebeius could lower uracil levels, altering systemic lipid metabolism, which may change the metabolic phenotype of secretory reticular fibroblasts in wounds, potentially leading to MK. …"
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7976
Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx
منشور في 2025"…</p>Results<p>Mice subjected to blunt chest trauma displayed emotional abnormalities and cognitive deficits. AKK treatment significantly alleviated anxiety-like behaviors and improved cognitive function, reduced pro-inflammatory cytokine levels in the hippocampus, and reshaped gut microbiota composition. …"
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7977
Data Sheet 6_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip
منشور في 2025"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
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7978
Data Sheet 9_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip
منشور في 2025"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
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7979
SPIRIT Schedule of Enrollment.
منشور في 2025"…</p><p>Results</p><p>The EX group showed increased EMG activation for the tibialis anterior, gastrocnemius medialis, rectus femoris, and biceps femoris in both anterior-posterior (2.23 MVIC%, 95% CI: 1.13 to 3.34, p < 0.001) and posterior-anterior directions (2.35 MVIC%, 95% CI: 1.80 to 2.91, p < 0.001) compared to CO group. Onset time decreased significantly in the EX group relative to CO group (anterior-posterior: -108.07 ms, 95% CI: -117.23 to -98.89, p < 0.001; posterior-anterior: -98.72 ms, 95% CI: -106.54 to -90.90, p < 0.001). …"
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7980
Table 1_How long do pathogens persist and survive in water? A systematic review.docx
منشور في 2025"…Viruses averaged 22 days of survival but could persist up to 1,095 days; Human Adenovirus and Porcine epidemic diarrhea virus were the most frequently studied viral pathogens, while Human Norovirus survived over 70 days in surface water at 37°C. Viral viability decreased significantly at extreme pH levels. Parasites/protozoans, such as Cryptosporidium parvum and Giardia lamblia only showed survival duration, averaged 30 days survival, enduring extreme conditions and often benefiting from biofilm association. …"