يعرض 5,781 - 5,800 نتائج من 8,285 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance levels decrease ))~', وقت الاستعلام: 0.50s تنقيح النتائج
  1. 5781

    Image 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff حسب Qianyi Zhou (6196383)

    منشور في 2025
    "…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…"
  2. 5782

    All source data of the paper “The mimicking and synergistic effects of magnetic fields on caloric restriction” حسب Xin Zhang (17292393)

    منشور في 2024
    "…In fact, MFs can replicate several CR benefits in <i>ob/ob</i> obese mice, such as reducing fatty liver, alleviating insulin resistance, and decreasing blood glucose levels. Furthermore, the combination of MFs with CR (MFs+CR) not only substantially improves lipid metabolism and overall liver function but also decreases fat mass while preserving lean mass. …"
  3. 5783
  4. 5784

    Figure 4 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma حسب Zelei Yang (18491142)

    منشور في 2025
    "…If there is no *, then the comparison was not significant. The color code for the cell cycle phase is on the far right of the graphs. …"
  5. 5785

    Table 1_Optimization of the scale-up production process for high-yield laccase from white-rot fungi.docx حسب Yaping Ma (3067050)

    منشور في 2025
    "…Dissolved oxygen (DO) was a crucial factor for high laccase yield, and its maintenance at a high level in the fermentation system significantly enhanced the enzyme activity. …"
  6. 5786

    Supplementary file 1_Does body weight support improve neural and biomechanical measures during treadmill gait in children with unilateral cerebral palsy?.docx حسب Rajit Banerjee (22481089)

    منشور في 2025
    "…Beta band EEG activation from 0% to 20% BWS showed a significant triple interaction increasing in the non-dominant and decreasing in the dominant hemisphere in TD, while increasing in both in CP. …"
  7. 5787

    Supplementary file 1_Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos.docx حسب Wentian Li (28857)

    منشور في 2025
    "…Neurotransmitter profiling showed significant reductions in glutamate, dopamine, and GABA levels.…"
  8. 5788

    Data Sheet 1_Population pharmacokinetics/pharmacodynamics and safety of YPEG-rhGH in elderly subjects.docx حسب Yajie He (20323682)

    منشور في 2025
    "…In the final model, AGE was identified as a significant covariate for K<sub>a</sub>, V<sub>1</sub>/F, and V<sub>max</sub>, while WEIGHT significantly influenced V<sub>max</sub>. …"
  9. 5789

    Image 1_T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting.jpeg حسب Jelena Pesic (21216791)

    منشور في 2025
    "…Chronic exposure to T2 cytokines following RV infection significantly decreased TSLP and IFNλ1 but increased IFNβ, specifically in asthmatic BECs.…"
  10. 5790

    DataSheet1_Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations.pdf حسب Ashelley Kettyllem Alves de Sousa (20293452)

    منشور في 2024
    "…Levels of mitochondrial and total superoxide anion (p < 0.01 and p < 0.05, respectively) and hydrogen peroxide (p < 0.001) were significantly elevated. …"
  11. 5791

    Image 4_Impact of DRG policy on the performance of tertiary hospital inpatient services in Chongqing, China: an interrupted time series study, 2020–2023.png حسب Yunyu Liu (11739052)

    منشور في 2025
    "…To evaluate both immediate and long-term effects of the DRG policy, we employed an interrupted time series analysis model to analyze changes in indicator levels and trends pre- and post-intervention.</p>Results<p>We found significant changes in the following indicators since the implementation of the DRG policy: case-mix index (CMI) level increased by 0.0661 (p = 0.02), but the trend decreased by 0.0071 (p < 0.001). …"
  12. 5792

    Image 1_Impact of DRG policy on the performance of tertiary hospital inpatient services in Chongqing, China: an interrupted time series study, 2020–2023.png حسب Yunyu Liu (11739052)

    منشور في 2025
    "…To evaluate both immediate and long-term effects of the DRG policy, we employed an interrupted time series analysis model to analyze changes in indicator levels and trends pre- and post-intervention.</p>Results<p>We found significant changes in the following indicators since the implementation of the DRG policy: case-mix index (CMI) level increased by 0.0661 (p = 0.02), but the trend decreased by 0.0071 (p < 0.001). …"
  13. 5793

    Image 2_Impact of DRG policy on the performance of tertiary hospital inpatient services in Chongqing, China: an interrupted time series study, 2020–2023.png حسب Yunyu Liu (11739052)

    منشور في 2025
    "…To evaluate both immediate and long-term effects of the DRG policy, we employed an interrupted time series analysis model to analyze changes in indicator levels and trends pre- and post-intervention.</p>Results<p>We found significant changes in the following indicators since the implementation of the DRG policy: case-mix index (CMI) level increased by 0.0661 (p = 0.02), but the trend decreased by 0.0071 (p < 0.001). …"
  14. 5794

    Image 3_Impact of DRG policy on the performance of tertiary hospital inpatient services in Chongqing, China: an interrupted time series study, 2020–2023.png حسب Yunyu Liu (11739052)

    منشور في 2025
    "…To evaluate both immediate and long-term effects of the DRG policy, we employed an interrupted time series analysis model to analyze changes in indicator levels and trends pre- and post-intervention.</p>Results<p>We found significant changes in the following indicators since the implementation of the DRG policy: case-mix index (CMI) level increased by 0.0661 (p = 0.02), but the trend decreased by 0.0071 (p < 0.001). …"
  15. 5795

    Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... حسب Yanmo Cai (22235563)

    منشور في 2025
    "…Pathological staining showed reduced renal tissue damage in mice, and electron microscopy revealed reduced pedunculopontine fusion and basement membrane thickening. YSHS decreased GRP78, PERK, p-PERK, CHOP, and Bax proteins and mRNA levels in renal tissues and MPC-5 cells (p < 0.05 and p < 0.01) while increasing the expression level of Nephrin protein and Bcl-2 mRNA (p < 0.05 and p < 0.01).…"
  16. 5796

    Image 4_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…We focused on 1.5 mM BHB, which reflects blood levels in mice and humans on a KD.</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  17. 5797

    Image 2_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…We focused on 1.5 mM BHB, which reflects blood levels in mice and humans on a KD.</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  18. 5798

    Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…We focused on 1.5 mM BHB, which reflects blood levels in mice and humans on a KD.</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  19. 5799

    Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... حسب Chase Garcia (21803576)

    منشور في 2025
    "…We focused on 1.5 mM BHB, which reflects blood levels in mice and humans on a KD.</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
  20. 5800

    Data_Sheet_1_Compound effects of biochar application and irrigation on soil water and temperature transport.docx حسب Fuchang Jiang (19966587)

    منشور في 2024
    "…<p>The issue of soil salinization poses a significant barrier to sustainable agricultural development, particularly in arid and semi-arid regions. …"