Table 5_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…</p>Results<p>Alizarin red staining and Calcium quantification experiments demonstrated that Isowighteone reduces aortic vascular calcification in mice and decreases calcification levels in Human aortic smooth muscle cells (HASMCs). …”

Table 6_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.docx by Yuanxi Mo (22090130)

“…</p>Results<p>Alizarin red staining and Calcium quantification experiments demonstrated that Isowighteone reduces aortic vascular calcification in mice and decreases calcification levels in Human aortic smooth muscle cells (HASMCs). …”

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…</p>Results<p>Alizarin red staining and Calcium quantification experiments demonstrated that Isowighteone reduces aortic vascular calcification in mice and decreases calcification levels in Human aortic smooth muscle cells (HASMCs). …”

Riboflavin inhibits growth and reduces virulence of <i>Cryptococcus neoformans in vitro</i> by membrane disruption and excessive accumulation of reactive oxygen species and exhibit... by Jian Huang (7250)

“…Finally, in mouse models of intranasal and intravenous infection, RF treatment significantly reduced the fungal burden in multiple organs, reduced lung and brain damage, and decreased the levels of plasma interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-4 in the early stage of infection. …”

Table 1_Psychological interventions mitigated occupational stress in high-risk workers in Shenzhen, China.xlsx by Naixing Zhang (308515)

“…After 2 years of intervention, the occupational stress detection rate decreased significantly to 47.82% (P < 0.001), while the high social support rate (19.68%) showed no significant change. …”

Full-length 16S rRNA gene amplicon analysis of gut microbiota in pigs fed with different diets in growing and finishing stages by Han-Sheng Wang (19858288)

“…Comparing fecal samples from pigs at 30 and 120 kg, pigs at 30 kg showed a significant increase in the relative abundance of <i>Clostridium butyricum</i>, whereas at 120 kg, the abundance of <i>Lactobacillus reuteri</i> and <i>Lactobacillus johnsonii</i> decreased. …”

<i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway by Ya-Li Zhou (21696911)

“…</p> <p>Disruptions in the Matriptase2-hepcidin axis emerge post-total liver radiation, marked by decreased Matriptase2 levels and heightened hepcidin levels. …”

Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... by Pengyu Wang (6680312)

“…</p>Results<p>Dapagliflozin alleviated diabetic liver injury by decreasing lipid deposition, oxidative stress levels, the inflammatary and apoptosis-related proteins and mRNA levels, while it also reducing blood glucose. …”

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... by Jingshuang Song (11340138)

“…Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Data Sheet 1_Qifuyin alleviates anxiety and depression in 3×Tg-AD mice by modulating neuroendocrine function.zip by Tianhao Yu (8120651)

“…In the QFY-treated group, plasma CORT levels were significantly decreased, whereas FSH and LH levels were significantly increased. …”

Data Sheet 1_Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites.docx by Tingyu Yang (10686507)

“…Additionally, OJO significantly reduced acetic acid and propanoic acid levels. …”

Data Sheet 1_Shenmai Injection enhances short-term outcomes in ischemic stroke patients after thrombolysis via AMPKα1.docx by Jing Wu (54032)

“…In the H2O2-induced cell model, SMI enhanced cell viability, reduced apoptosis, and decreased the levels of malondialdehyde (MDA) and reactive oxygen species (ROS). …”

Data Sheet 1_Evaluation of tolerability and safety of transcranial electrical stimulation with gel particle electrodes in healthy subjects.pdf by Chuangchuang Chang (20179632)

“…Additionally, fatigue increased, and energy levels decreased on VAMS-R with longer durations. …”

Supplementary file 1_Effects of non-HDL-C and statin therapy on mortality in ARDS: a retrospective cohort study.docx by Haiming Hu (12451365)

“…Both univariate (HR, 0.48; 95% CI, 0.41–0.58; p < 0.001) and multivariate (HR, 0.49; 95% CI, 0.41–0.58; p < 0.001) Cox regression analyses revealed that statin therapy significantly decreased short-term mortality. Subsequent subgroup analyses further indicated that the beneficial effect of statins was more evident in patients with elevated non-HDL-C levels.…”

Image 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.jpeg by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Image 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf by Jinque Luo (9645983)

“…Further western blotting analysis showed 5-DR decreased the levels of NLRP3, cleaved caspase-1, and mature IL-1β in mice and J774A.1 cells exposed to LPS. …”

Data Sheet 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf by Jinque Luo (9645983)

“…Further western blotting analysis showed 5-DR decreased the levels of NLRP3, cleaved caspase-1, and mature IL-1β in mice and J774A.1 cells exposed to LPS. …”

Image 1_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.pdf by Haddad A. El Rabey (22248019)

“…The liver and heart tissues were also significantly injured by hypercholesterolemia. Administration of atorvastatin and safflower markedly ameliorated the biochemical and histological abnormalities associated with induced hyperlipidemia, restoring them to near-normal levels. …”