Table 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx by Yiwen Li (354034)

“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”

Table 2_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx by Yiwen Li (354034)

“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... by Dilpreet Kour (10872766)

“…Subsequent brain tissue analysis revealed that IBC upregulated autophagic proteins to reduce the brain’s amyloid beta levels, resulting in decreased expression of neuroinflammation markers.…”

Table 1_Clinical characteristics and treatment of hepatic portal venous gas: case series and literature review.docx by Hao-Ran Wei (18833288)

“…Patients presented with decreased red blood cell and hemoglobin counts, and increased white blood cell, neutrophil, C-reactive protein, and D-dimer levels. …”

Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx by Chen-xiao Liu (22750118)

“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”

Metabolic flux analysis revealed key roles of ArcB in ADI pathway and IlvC in BCAA biosynthesis during <i>streptococcus suis</i> anaerobic growth and infection by Hao Tang (44155)

“…Both Δ<i>arcB</i> and Δ<i>ilvC</i> showed attenuation in mice with decreased lethality, bacterial loads in tissues and cytokine levels in serum, with the hypoxia-induced gene up-regulated in tissues. …”

<b>Metabolic flux analysis revealed </b><b>key roles of </b><b>ArcB</b><b> in ADI pathway and IlvC in BCAA </b><b>biosynthesis </b><b>during </b><b><i>Streptococcus suis</i></b><b>... by Hao Tang (21218903)

“…Both <a href="" target="_blank">Δ<i>arcB</i> </a>and Δ<i>ilvC</i> showed attenuation in mice with decreased lethality, bacterial loads in tissues and cytokines levels in serum, with the <a href="" target="_blank">hypoxia</a>-induced gene up-regulated in tissues. …”

PMS repressed ferroptosis in T2DM mice. by Hongmin Zhao (20710544)

“…(c,d) Perl’s Prussian blue staining results demonstrated that the deposition of free iron in the pancreas of T2DM mice was significantly decreased following PMS intervention. (e-h) PMS intervention reduces levels of ROS (e), MDA (f), and 4-HNE (g), and decreased total Iron (h) level in pancreatic tissue of T2DM Mice. …”

Table 1_Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey.docx by Haimeng Wu (20416217)

“…Threshold effect analysis revealed a threshold point corresponding to natural log-transformed caffeine value >3.74 (equivalent to ~41 mg/day), above which Klotho levels demonstrated a more pronounced decline. Subgroup analyses indicated that this association was more significant in participants with sedentary activity >480 min and without hypertension.…”

Supplementary Material for: High-sensitivity Troponin I Measurement in a Large Contemporary Cohort: Implications for Clinical Care by Esau D. (20563829)

“…Male sex, higher HDL-C, higher Hgb A1c, decreasing eGFR, and increasing systolic blood pressure were significant predictors of increased hsTnI. …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”

Data Sheet 1_Global, regional, and national burden and trends of intracerebral hemorrhage among adolescents and young adults aged 15–39 years from 1990 to 2021: a comprehensive tre... by Xuanchen Liu (12188147)

“…Background<p>Intracerebral hemorrhage (ICH) poses a significant health challenge, notably affecting adolescents and young adults (AYAs) aged 15–39 years. …”

Hemostatic changes following COVID-19 vaccination: Do they promote a pro-thrombotic state? by Tarinee Rungjirajittranon (6268034)

“…BNT162b2 group platelet counts increased significantly on day 7 (<i>p</i> = .010). TGA parameters in the ChAdOx1-S group decreased significantly in ETP levels (<i>p</i> = .007) and peak concentrations (<i>p</i> = .041) over time while those of the BNT162b2 group were stable (median ETP levels and peak concentrations; <i>p</i> > .05). …”

Effect of COVID-19 infection on thyroid function status and clinical indexes among hypothyroid outpatients by Bingxin Li (1876975)

“…In HT group, thyroid-stimulating hormone (TSH) levels decreased significantly compared to pre-infection levels (<i>p</i> = 0.013), while free triiodothyronine (FT3) levels increased at D90 compared to both D30 post-infection and pre-infection levels (<i>p</i> < 0.001 and <i>p</i> = 0.005). …”

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... by Jing Lu (120666)

“…Background<p>Cardiovascular disease (CVD) is one of the leading global causes of death, and serum iron (SI) levels may be associated with the mortality of CVD. …”

Table 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -induced... by Yanping Wang (275956)

“…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…”

Table 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -induced... by Yanping Wang (275956)

“…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…”

Data Sheet 1_The efficacy of ophiopogonanone B in treating the cough in mice infected with Mycoplasma pneumoniae.docx by Nan-Nan Liu (12093551)

“…Subsequent immunohistochemistry and RT-PCR revealed a significant reduction (P < 0.01 or P < 0.05) in the proteins and mRNA expression levels of TRPA1, SP, and CGRP in the lung tissue of mice treated with high and medium doses of ophiopogonanone B.…”

Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus by Jian Sun (27858)

“…Renal biopsies from LN (<i>n</i> = 24) were collected for immunohistochemical analysis of Lyn level.</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …”

Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d... by Sathivel Thivijan (20393742)

“…High-Performance Liquid Chromatography analysis revealed that while tartaric acid levels remained constant, malic acid content decreased, and acetic acid was produced by all strains. …”