Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled... حسب Jilei Hu (10156880)

"…However, curcumin significantly reduced the levels of HCT and hemoglobin compared to that in the placebo group after the 6-week intervention on the plateau (p < 0.05). …"

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx حسب Mehri Hajiaghayi (19822665)

"…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …"

Table1_GLYCINE betaine and seaweed-based biostimulants improved leaf water status and enhanced photosynthetic activity in sweet cherry trees.docx حسب Sílvia Afonso (20456483)

"…The Chlorophyll_a/Chlorophyll_b ratio, ranging from 2 to 4, indicated a greater capacity for light absorption and lower stress levels in treated leaves. Soluble sugar and starch content decreased during fruit development in both cultivars and years; however, biostimulants increased these contents, with increments of approximately 15% to 30% in leaves treated with EM. …"

Table 1_Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with... حسب Lei Jiang (73366)

"…</p>Results<p>The 6MWT showed significantly greater improvement in the HIIT group compared to the MCT group (P = 0.0024). …"

Data Sheet 1_Impact of bacteroides uniformis on fatty liver hemorrhagic syndrome in dawu golden phoenix laying hens: modulation of gut microbiota and arachidonic acid metabolism.do... حسب Yu Zhang (12946)

"…Moreover, targeted metabolomic analysis showed that supplementation of B. uniformis significantly elevated 6-keto-PGF_1α and AA levels, along with significantly reduced levels of thromboxane B₂ (TXB₂), leukotriene D₄ (LTD₄), 8-isoprostaglandin F_2α (8-iso-PGF_2α), 12S-hydroxyeicosatetraenoic acid (12S-HETE), 15S-hydroxyeicosatetraenoic acid (15S-HETE), 9-S-hydroxy-octadecadienoic acid (9S-HODE), and 13-S-hydroxy-octadecadienoic acid (13S-HODE) (p < 0.05). …"

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx حسب Aierpati Moheteer (21522284)

"…Furthermore, the DSP nanoparticles-H group significantly decreased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBIL), direct bilirubin (DBIL), and alkaline phosphatase (ALP). …"

Proteomic and Functional Analysis on Endothelial Cell Heterogeneity Identifies Key Regulators in Hyperglycemia-Induced Dysfunction-Supplemental Materials حسب Morgan Minjares (21143203)

"…Furthermore, under high glucose conditions, WARS1 was increased while SOD2 was decreased. Reversing WARS1 or SOD2 expression levels improved HDMVEC migration and permeability functions. …"

Image 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.png حسب Zhi Lin (281756)

"…Patients with grade III–IV acute graft-versus-host disease (GVHD) exhibited significantly lower HDL-C levels compared to those without GVHD. …"

Table 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.docx حسب Zhi Lin (281756)

"…Patients with grade III–IV acute graft-versus-host disease (GVHD) exhibited significantly lower HDL-C levels compared to those without GVHD. …"

Image 1_Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress.jpeg حسب Lianzhe Wang (6202643)

"…Silencing TalncR9 in wheat reduced drought tolerance, decreased soluble sugar and proline levels, and increasing MDA levels. …"

Table 1_Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress.xlsx حسب Lianzhe Wang (6202643)

"…Silencing TalncR9 in wheat reduced drought tolerance, decreased soluble sugar and proline levels, and increasing MDA levels. …"

Data Sheet 1_Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease.docx حسب Yifan Zhang (119570)

"…The MR analysis results showed a positive correlation between higher genetic predictions of dopamine 3-O-sulfate levels and the risk of Parkinson’s disease. In contrast, the reverse MR analysis found that Parkinson’s disease susceptibility significantly increased dopamine 3-O-sulfate levels.…"

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. حسب Weiran Huang (8934899)

"…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. IOP decreased 6 hours post-injection and by day 1 had returned to near baseline levels. …"

Data Sheet 1_Modeling lymphocyte subset dynamics after ublituximab therapy in patients with multiple sclerosis: an Italian prospective study.pdf حسب Aurora Zanghì (9202094)

"…Mixed-effects models showed a significant effect of time on all lymphocyte subsets. …"

Image 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif حسب Felicia Menicucci (7495508)

"…</p>Results<p>The PS II efficiency decreased in response to red LEDs treatment only. The highest levels of polyphenol and chlorophyll content were registered in response to blue LEDs exposure in both cultivars. …"

Table 2_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

"…In the CIA mouse model, transdermal application of hcBAC-exos led to notable decreases in ankle swelling and the serum levels of IL-1β and TNFα (P < 0.5). …"

Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Image 3_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..jpeg حسب Felicia Menicucci (7495508)

"…</p>Results<p>The PS II efficiency decreased in response to red LEDs treatment only. The highest levels of polyphenol and chlorophyll content were registered in response to blue LEDs exposure in both cultivars. …"