يعرض 7,481 - 7,500 نتائج من 8,285 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance levels decrease ))~', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 7481

    Image 1_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif حسب Chen Wang (88408)

    منشور في 2025
    "…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …"
  2. 7482

    Table 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx حسب M. Elakkya (21760439)

    منشور في 2025
    "…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…"
  3. 7483

    Image 3_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif حسب Tengfei Tian (1793545)

    منشور في 2025
    "…In addition, the hBD-2 protein was negatively correlated with the Lund–Mackay CT score and was positively correlated with the neutrophil levels in CRSwNP. The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …"
  4. 7484

    Table 1_Declining trends in sweetness of the diet in the United Kingdom: 2008/9–2018/19.docx حسب Inga Kutepova (20873687)

    منشور في 2025
    "…Overall, the decline in ASE was larger for beverages than foods (ASE values declined 20.7% for beverages vs. 4.4% for foods), although both decreased significantly (p-value < 0.01). Dietary sweetness has changed in the UK, due to a combination of consumer behavior, reformulations, policies, public health awareness programs, and media campaigns, emphasizing its multifactorial nature.…"
  5. 7485

    Presentation_1_The impact of challenge and hindrance stressors on knowledge hiding: the mediating role of job crafting and work withdrawal.pdf حسب Le Wang (165105)

    منشور في 2024
    "…The findings indicate that both challenge and hindrance stressors significantly increase knowledge hiding, with hindrance stressors exerting a more pronounced effect. …"
  6. 7486

    Image 5_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

    منشور في 2025
    "…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …"
  7. 7487

    Image 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif حسب Tengfei Tian (1793545)

    منشور في 2025
    "…In addition, the hBD-2 protein was negatively correlated with the Lund–Mackay CT score and was positively correlated with the neutrophil levels in CRSwNP. The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …"
  8. 7488

    Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf حسب Lisa Zierke (20682053)

    منشور في 2025
    "…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…"
  9. 7489

    Image 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

    منشور في 2025
    "…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …"
  10. 7490

    Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents حسب Yujuan Li (554062)

    منشور في 2024
    "…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …"
  11. 7491

    Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure حسب figshare admin karger (2628495)

    منشور في 2025
    "…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …"
  12. 7492

    Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf حسب Yanyan Yang (412382)

    منشور في 2024
    "…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …"
  13. 7493

    Image 14_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg حسب Chen Wang (88408)

    منشور في 2025
    "…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …"
  14. 7494

    Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif حسب M. Elakkya (21760439)

    منشور في 2025
    "…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…"
  15. 7495

    Table 1_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le... حسب Ting Yang (189879)

    منشور في 2025
    "…<p>Optimizing fermentation duration is critical for producing high-quality cigar tobacco leaves This study examines changes in microorganisms and metabolites during CTL fermentation at four time points: 0 days (T0), 25 days (T1), 50 days (T2), and 75 days (T3). We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …"
  16. 7496

    Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress حسب Serina Yan (22416354)

    منشور في 2025
    "…</p><p dir="ltr">Results showed that 50 µM CBX prolonged calcium signal duration (FWHM), while 100 µM CBX shortened it toward control levels. Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …"
  17. 7497

    Table 1_Study on the effect of different types of sugar on proliferation and inflammatory in goose fatty liver.docx حسب Shuang Yi (8698824)

    منشور في 2025
    "…Primary hepatocytes isolated from 21-day-old geese were treated with 30 mmol/L glucose or fructose, combined with CPT1A gene interference. Fructose significantly enhanced lipid accumulation in overfed geese (p < 0.05). …"
  18. 7498

    Image 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif حسب M. Elakkya (21760439)

    منشور في 2025
    "…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…"
  19. 7499

    Table 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx حسب M. Elakkya (21760439)

    منشور في 2025
    "…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…"
  20. 7500

    Image 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.jpeg حسب M. Elakkya (21760439)

    منشور في 2025
    "…Under salt and osmotic stress, A. chroococcum W5 metabolomic profiling revealed adaptive responses, including elevated levels of osmoprotectants (proline, glycerol) and oxidative stress markers such as 2-hydroxyglutarate, while putrescine and glycine decreased.…"