Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

“…Statistical analyses were conducted using Prism software to identify significant group differences.</p>Results<p>We found that differential expressional genes and proteins relating to circadian rhythm were enriched in proteomic or transcriptomic. …”

Data Sheet 2_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf by Andrey Elchaninov (3122742)

“…Introduction<p>Mammalian liver regeneration is a complex process, the regulation of which involves many mechanisms. …”

Data Sheet 1_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf by Andrey Elchaninov (3122742)

“…Introduction<p>Mammalian liver regeneration is a complex process, the regulation of which involves many mechanisms. …”

Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx by Chen Shaopeng (20576303)

“…Introduction<p>The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.…”

Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

“…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19⁺ B cells and CD14⁺ monocytes, but significantly decreased on CD56⁺ NK cells.We identified a distinct CD226⁺CD19⁺ B cell subset that exhibited pathogenic features in pSS. …”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”

Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif by Soon-Young Lee (4721136)

“…<p>WHO reported that asthma was responsible for 455,000 deaths in 2019 and asthma patients was evaluated 262 million in May 2023. …”

DataSheet1_Anaerobic membrane bioreactor (AnMBR) with external ultrafiltration membrane for the treatment of sugar beet vinasse.PDF by Beatriz Egerland Bueno (20143764)

“…<p>Vinasse, a by-product of ethanol production, is generated at significant rates. …”

Supplementary Material: Spent hemp biomass as a feed ingredient for beef steers: effects on performance, blood parameters, behavior, cannabinoid residues, and consumer exposure lev... by Agung Irawan (14145081)

“…<p dir="ltr">Prior studies in ruminants demonstrated the safety of feeding spent hemp biomass (SHB) to lambs and dairy cows. …”

Table2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table13_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table12_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table3_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table9_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Image1_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table7_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table6_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table11_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table8_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”

Table5_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…Additionally, we validated hub gene expression in both an animal model and serum samples from PCOS patients using qRT-PCR.</p>Results<p>IVW analysis revealed significant associations between 10 hub genes and the risk of PCOS: CD93 [P= 0.004; OR 95%CI= 1.150 (1.046, 1.264)], CYBB [P= 0.013; OR 95%CI= 1.650 (1.113,2.447)], DOCK8 [P= 0.048; OR 95%CI= 1.223 (1.002,1.494)], IRF1 [P= 0.036; OR 95%CI= 1.343 (1.020,1.769)], MBOAT1 [P= 0.033; OR 95%CI= 1.140 (1.011,1.285)], MYO1F [P= 0.012; OR 95%CI= 1.325 (1.065,1.649)], NLRP1 [P= 0.020; OR 95%CI= 1.143 (1.021,1.280)], NOD2 [P= 0.002; OR 95%CI= 1.139 (1.049,1.237)], PIK3R1 [P= 0.040; OR 95%CI= 1.241 (1.010,1.526)], PTER [P= 0.015; OR 95%CI= 0.923 (0.866,0.984)]. …”