Data Sheet 1_Dietary seaweed extract mitigates oxidative stress in Nile tilapia by modulating inflammatory response and gut microbiota.docx by Muhammad A. B. Siddik (6569957)

“…Fish fed the GE diet also showed a significantly lower lipid peroxidation by decreased malondialdehyde level when compared to control (p < 0.05). …”

Data Sheet 1_Prognostic alternative mRNA splicing in lung adenocarcinoma.xlsx by Panke Su (22636301)

“…High-risk patients, identified by the signature, showed significantly decreased stromal, immune, and combined scores; increased tumor purity (P< 0.001); a reduced prevalence of various immune cell types; diminished immune cell activity; and decreased expression of immune checkpoint genes. …”

Table 1_Prognostic alternative mRNA splicing in lung adenocarcinoma.xlsx by Panke Su (22636301)

“…High-risk patients, identified by the signature, showed significantly decreased stromal, immune, and combined scores; increased tumor purity (P< 0.001); a reduced prevalence of various immune cell types; diminished immune cell activity; and decreased expression of immune checkpoint genes. …”

Table2_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.xlsx by Mengen Nie (20143902)

“…Compared with the CF treatment, a medium ratio (50%) of organic fertilizer substitution significantly reduced soil alkalization (by 3.05%), improved soil nutrients, enhanced soil enzyme activities, and increased sorghum yield (P < 0.05). …”

Table1_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.docx by Mengen Nie (20143902)

“…Compared with the CF treatment, a medium ratio (50%) of organic fertilizer substitution significantly reduced soil alkalization (by 3.05%), improved soil nutrients, enhanced soil enzyme activities, and increased sorghum yield (P < 0.05). …”

DataSheet1_SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice.docx by Nerea Martos-Guillami (19809315)

“…At the end of the experiment, kidney and heart were isolated for histological and gene expression studies as well as for intrarenal RAS state assessment.</p>Results<p>Semaglutide combined with ramipril and/or empagliflozin significantly decreased albuminuria but only when combined with both compounds, semaglutide further decreased blood glucose, glomerular hyperfiltration in male mice and glomerular mesangial matrix expansion. …”

Table 1_Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats.docx by Tabusi Manaer (10689669)

“…The OGTT AUC decreased by 40.1% (p < 0.001), and HbA1c levels fell by 22.9% (p < 0.01). …”

Table 1_Distinct response patterns of endothelial markers to the BNT162b2 mRNA COVID-19 booster vaccine are associated with the spike-specific IgG antibody production.docx by Beatriz Castro-Robles (20506802)

“…</p>Results<p>We identified two significantly distinct profiles of endothelial markers response, characterized by either increased or decreased serum levels of endocan and sVCAM. …”

Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx by Dan-Ni Yang (17642947)

“…Introduction<p>The diagnostic value of pleural fluid carcinoembryonic antigen (CEA) for malignant pleural effusion (MPE) has been well recognized. …”

Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip by Quan Lin (5958)

“…In vitro hypoxia cell models, SQOR knockdown experiments and nude mouse xenograft models were used to verify the regulatory function of SQOR on ferroptosis.</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Presentation 1_Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.pptx by Ryohei Yamamura (20386047)

“…Background<p>The advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). …”

Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx by Chengyu Yang (10223976)

“…The signaling pathways modulated by SXD were elucidated using transcriptomics analysis complemented by network analysis.</p>Results<p>SXD treatment ameliorates decreased splenic and thymic organ indexes, as well as decreased lymphocyte number in the spleen in immunosuppressed mice. …”

Image 1_Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.pdf by Huakai Wang (505567)

“…The IPEC-J2 cells were treated with or without VK and LPS for 24 h and analyzed with various assays.</p>Results<p>Morphological analysis revealed that VK significantly restored the decreased villus height and ratio of villus height to crypt depth induced by LPS. …”

Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Table 5_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

Prevalence of Vision Loss in North Africa and Middle East in 2020: Magnitude and Temporal Trends by Vision Loss Expert Group of the Global Burden of Disease Study (20987841)

“…</p> <p>Although the absolute numbers of people with blindness and MSVI have increased between 1990 and 2020 in NAME region, the overall prevalence and the age standardized prevalence in those aged 50+ years have decreased significantly for the same period.…”

Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”

DataSheet1_Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis.PDF by Hongmei Yu (584700)

“…Comparative analyses of the gut microbiota, serum metabolites, and kidney transcriptomics before and after drug administration were performed.</p>Results<p>After treatment with HKC, EB, and their combination for 4 weeks, the urinary albumin-to-creatinine ratios decreased significantly in the db/db mice with DN. …”

Supplementary Figures for AJP-Integr Reg Comp Physiol R-00035-2025R1 by Joshua Huot (20868279)

“…At molecular level, the tumor hosts displayed reduced estimations of muscle protein synthesis and increased muscle protein ubiquitination, in disagreement with decreased muscle ubiquitin ligase mRNA expression.</p><p dir="ltr"><b>Conclusions.…”