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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significance p » significance _ (Expand Search), significance b (Expand Search), significance set (Expand Search)
p decrease » _ decrease (Expand Search), a decrease (Expand Search), pa decreased (Expand Search)
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18961
Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
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18962
Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
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18963
Data Sheet 1_Virus-like particles containing the extracellular domain of G protein in combination with a CTL peptide of M2 elicit protection against respiratory syncytial virus inf...
Published 2025“…Compared with the UV-RSV control group, both G<sub>ECD</sub>/M2<sub>82-90</sub>-VLPs and G<sub>ECD</sub>-VLPs groups exhibited significantly increased Th1-type cytokine levels and decreased Th2-type cytokine concentrations (P<0.05, P<0.001). …”
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18964
Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf
Published 2025“…The experiment lasted for 24 weeks.</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …”
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18965
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
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18966
DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF
Published 2024“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”
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18967
Long-Term Effects of Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 3- and 6-Year Results of the ADJUVITE Trial
Published 2025“…The mean dose of methotrexate decreased significantly from 11.3 ± 4.4 mg/week at the end of the trial to 5.2 ± 6.2 mg/week at the last follow-up (<i>p</i> = 0.002). …”
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18968
Supplementary file 1_Ecosystem carbon storage and carbon metabolizing microorganisms in three types of grasslands on the Qinghai-Tibet Plateau.docx
Published 2025“…The relative abundance of carbon-fixing microorganisms Thiobacillus, Mesorhizobium, Azospirillum, and Methylibium significantly increased grassland carbon storage, while the relative abundance of chitinase-producing microorganisms Cellulomonas and Stenotrophomonas significantly decreased it.…”
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18969
Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc
Published 2025“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”
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18970
Supplementary file 1_Colonizable probiotic Lactobacillus paracasei R3 enhances ICI therapy via modulating PBMCs differentiation.docx
Published 2025“…L.p R3 significantly elevated the levels of macrophages, CD4<sup>+</sup>T cells and CD8<sup>+</sup>T cells in PBMCs while simultaneously decreasing the level of programmed cell death protein 1 (PD-1) on the surface of CD4<sup>+</sup>T cells and CD8<sup>+</sup>T cells. …”
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18971
Image 2_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…GDM patients who carried H1H1/AG+GG genotype were 1.97-fold increased risk to develop GDM (95% CI: 1.140-3.414, P = 0.015). H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…”
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18972
Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…GDM patients who carried H1H1/AG+GG genotype were 1.97-fold increased risk to develop GDM (95% CI: 1.140-3.414, P = 0.015). H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…”
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18973
Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx
Published 2025“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”
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18974
Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx
Published 2025“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”
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18975
Table 3_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…Some low-SDI countries have achieved minimal theoretical disease burdens, whereas certain high-SDI countries lag in reducing their neonatal disease burdens.</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
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18976
Image 1_The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells.tif
Published 2025“…E2F1 was identified as an upstream regulator of EIF4EBP1, with knockdown of E2F1 significantly decreasing EIF4EBP1 promoter activity and binding. …”
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18977
<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b>
Published 2025“…Associations with glycemic and cognitive measures were assessed.</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …”
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18978
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…Cell proliferation, migration, and angiogenesis were determined using CCK-8 assays, transwell assays, and tubule formation assays, respectively.</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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18979
Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx
Published 2025“…In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
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18980
Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx
Published 2025“…In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”