يعرض 20,621 - 20,640 نتائج من 20,810 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance p decrease ))~', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 20621

    Image 3_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif حسب Tong Luo (458639)

    منشور في 2025
    "…Lung RNA sequencing identified differentially expressed genes and enriched pathways related to oxidative stress and inflammation.</p>Results<p>CNS significantly improved survival, reduced pulmonary edema, and alleviated lung inflammation and locomotor deficits in LPS-challenged mice. …"
  2. 20622

    Supplementary file 1_Association of prenatal trajectories of depressive and anxiety symptoms with neurodevelopment of children aged 0-24 months: A prospective study.docx حسب Ruoqing Chen (9952075)

    منشور في 2025
    "…Background<p>Prenatal depression and anxiety can significantly impact a child’s neurodevelopment. …"
  3. 20623

    Image 1_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png حسب Zijie Yang (6330086)

    منشور في 2024
    "…Multiple sexual partners, seeking partners in core venues, receptive or both sexual roles, drug abuse, absence of HIV test, unprotected anal intercourse (UAI), and lower education levels were associated with elevated HIV risk among MSM.</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …"
  4. 20624

    Table_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... حسب Mingzheng Duan (11630632)

    منشور في 2024
    "…Soil sample collected from the uncultivated field was used as the control (CK).</p>Results<p>Metabarcoding sequencing showed high bacterial alpha diversity during the cultivation of Tian-ma (0 Year) and the period of deterioration of soil bacterial community. (1 Year), with decreased anaerobic bacterial abundance and increased copiotrophic bacterial abundance. …"
  5. 20625

    Image 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif حسب Shaolian Zang (11987905)

    منشور في 2025
    "…Intracerebroventricular (ICV) injections of a BDNF-overexpressing lentiviral vector or a negative control (NC) were used to investigate the role of central BDNF in regulating puberty onset and reproductive function.</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. …"
  6. 20626

    Image 1_Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation.tif حسب Jingyi Hou (698975)

    منشور في 2025
    "…Experimental validation of hub mitoDEGs, immune cell markers (F4/80, CD163 and CD86), and apoptosis-related proteins (BAX/BCL-2 and cleaved caspase-3) was conducted in MI mice, and the association with cardiac function was explored.</p>Results<p>MitoDEGs in the MI group were significantly enriched in pathways related to mitochondrial transport and gene expression. …"
  7. 20627

    Table 3_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv حسب Siying Wei (5990276)

    منشور في 2025
    "…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …"
  8. 20628

    Image 2_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png حسب Zijie Yang (6330086)

    منشور في 2024
    "…Multiple sexual partners, seeking partners in core venues, receptive or both sexual roles, drug abuse, absence of HIV test, unprotected anal intercourse (UAI), and lower education levels were associated with elevated HIV risk among MSM.</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …"
  9. 20629

    Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…Chip-qPCR was employed to further elucidate the binding sites of the transcription factor c-Jun.</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. …"
  10. 20630

    Image 4_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png حسب Zijie Yang (6330086)

    منشور في 2024
    "…Multiple sexual partners, seeking partners in core venues, receptive or both sexual roles, drug abuse, absence of HIV test, unprotected anal intercourse (UAI), and lower education levels were associated with elevated HIV risk among MSM.</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …"
  11. 20631

    Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... حسب Hongbo Cheng (2848235)

    منشور في 2024
    "…Chip-qPCR was employed to further elucidate the binding sites of the transcription factor c-Jun.</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. …"
  12. 20632

    Table1_Identification and expression profiling of neuropeptides and neuropeptide receptor genes in a natural enemy, Coccinella septempunctata.DOCX حسب ShunDa Han (19822464)

    منشور في 2024
    "…During diapause induction, the mRNA abundance of AKH was notably higher on the 10th day compared to non-diapause females, but decreased by the 20th day. In contrast, GPHA showed lower expression levels on the 5th day of diapause induction compared to non-diapause females, but increased significantly by the 15th and 20th days. …"
  13. 20633

    Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2... حسب Junhong Yang (7807046)

    منشور في 2025
    "…Background<p>While international cooperation in blood donor safety surveillance is growing, data from China’s national network remains unpublished. …"
  14. 20634

    Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx حسب Siying Wei (5990276)

    منشور في 2025
    "…</p>Conclusion<p>This study highlights marked disparities in the disease burden among age groups across diverse SDI regions. …"
  15. 20635

    Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... حسب Mingzheng Duan (11630632)

    منشور في 2024
    "…Soil sample collected from the uncultivated field was used as the control (CK).</p>Results<p>Metabarcoding sequencing showed high bacterial alpha diversity during the cultivation of Tian-ma (0 Year) and the period of deterioration of soil bacterial community. (1 Year), with decreased anaerobic bacterial abundance and increased copiotrophic bacterial abundance. …"
  16. 20636

    Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

    منشور في 2025
    "…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"
  17. 20637

    Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

    منشور في 2025
    "…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"
  18. 20638

    Mitigating toxicity of arsenic in sunflower (<i>Helianthus annuus</i> L.) with phosphate rock and farmyard manure using contrasting soil textures حسب Muhammad Awais Piracha (21234904)

    منشور في 2025
    "…</p><p></p> <p>Arsenic solubility in soil significantly affected by soil texture, with clay soil exhibiting the least As availability followed by loam and sand texture.…"
  19. 20639

    Data Sheet 1_Improving tea quality and fruit yield through intercropping with climbing plants.pdf حسب Qing Liao (1466149)

    منشور في 2025
    "…<p>Integrating high-value climbing fruit crops into tea (Camellia sinensis) systems offers potential to improve tea quality and diversify income, yet the density-dependent effects on both crops remain unquantified. …"
  20. 20640

    DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

    منشور في 2025
    "…Upregulation of DYNLT3 expression markedly decreased the expression of Wnt signaling pathway-related proteins (Dvl2, Dvl3, p-LRP6, Wnt3a, Wnt5a/b, Naked1, Naked2, β-catenin and C-Myc) and EMT-related proteins (N-cadherin, SOX2, OCT4, vimentin and Snail), and increased the expression of E-cadherin and Axin1. …"