Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario حسب Karoliny Nune Santos (21752603)

"…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. …"

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx حسب Jung Hoon Cha (19723588)

"…Macrophage profiling was performed using single-nuclei RNA sequencing and flow cytometry.</p>Results<p>CHIT1 expression in fibrotic liver tissues was significantly correlated with the extent of liver fibrosis, macrophages, and inflammation. …"

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip حسب Jung Hoon Cha (19723588)

"…Macrophage profiling was performed using single-nuclei RNA sequencing and flow cytometry.</p>Results<p>CHIT1 expression in fibrotic liver tissues was significantly correlated with the extent of liver fibrosis, macrophages, and inflammation. …"

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

"…Single-nucleus RNA sequencing (snRNA-seq) was employed to delineate cell type-specific oxidative phosphorylation activity and transcriptional profiles.</p>Results<p>Transcriptomic analysis identified 130 DEGs between schizophrenia and controls, significantly enriched in oxidative phosphorylation and mitochondrial respiration pathways. …"

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

"…Single-nucleus RNA sequencing (snRNA-seq) was employed to delineate cell type-specific oxidative phosphorylation activity and transcriptional profiles.</p>Results<p>Transcriptomic analysis identified 130 DEGs between schizophrenia and controls, significantly enriched in oxidative phosphorylation and mitochondrial respiration pathways. …"

Table 1_Impact of different 3D regions of interest on quantifying dynamic lumbar vertebral microstructure in ovariectomized rats—a micro-CT study.doc حسب Huihui Xu (778437)

"…Quantitative analyses of bone microarchitecture parameters were conducted separately for the central ROI (ROI 1) and overall ROI (ROI 2).</p>Results<p>The results indicated that the Tb.N of baseline group rats for ROI 1 was significantly lower than that for ROI 2. …"

Table 1_Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice.doc حسب Wen Dong (467988)

"…</p>Discussion<p>The SAL strain intervention significantly improved redox homeostasis, restored intestinal barrier integrity, and reversed gut dysbiosis, highlighting its dual regulatory role in anti-aging mechanisms. …"

Supplementary file 1_Disproportionality analysis of taste disorders using the FDA adverse event reporting system and Japanese adverse drug event report databases.docx حسب Yoji Kyotani (599686)

"…The hazard for clarithromycin remained constant throughout administration, while the hazards for the other drugs decreased over time. Logistic regression analysis confirmed significant associations between the drugs and taste disorders, even after adjusting for age and sex. …"

Soil plant available silicon from a bamboo forest on karst mountain in southwest China differs between wet and dry seasons حسب Bin Xu (10691)

"…</p>…"

Data Sheet 1_CARTOON-based educational intervention for children to foster hygiene knowledge and emotional resilience in preschool children: a randomized controlled trial.pdf حسب Philipp Steinbauer (10792029)

"…Additionally, anxiety scores significantly decreased in the intervention group post-intervention compared to baseline (2.2 ± 1.7 vs. 5.6 ± 2.5; p = .01). …"

Supplementary file 1_Evaluation of drug interactions in outpatients taking antipsychotic medications.docx حسب Bshra A. Alsfouk (13259895)

"…The most frequent potential adverse effects were increased sedation (36%), hyperglycemia (15%) and decreased blood pressure (14%). Receiving polypharmacy (i.e., ≥5 drugs concomitantly administered) was significantly associated with an increased probability of drug interaction occurrence (OR = 42, P = 0.0026). …"

Table 1_Association of the ROX index with mortality in sepsis patients: a retrospective study.docx حسب Jiali Wu (701228)

"…</p>Conclusion<p>In patients with sepsis, a higher ROX index is associated with significantly lower mortality rates and shorter ICU and hospital stays. …"

Table 1_Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with... حسب Lei Jiang (73366)

"…Furthermore, we analyzed 6MWT association to gut microbiome and metabolites with group differences.</p>Results<p>The 6MWT showed significantly greater improvement in the HIIT group compared to the MCT group (P = 0.0024). …"

Table 1_Association between serum anion gap trajectory and mortality in hospitalized patients with sepsis: an analysis of the MIMIC-IV database.docx حسب Lijuan Jing (20431757)

"…In fully adjusted models, Class 3 exhibited a significantly increased risk of ICU mortality [HR=1.72, (95% CI 1.43-2.07), P<0.001] and hospital mortality [HR=1.64, (95% CI 1.39-1.94), P<0.001] relative to Class 1. …"

Figure 7 from Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain حسب Stamatia C. Vorri (19563842)

"…<p>Single-chain proximal IL7Rα CAR-T cells have decreased <i>in vivo</i> antileukemia activity. …"

Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc... حسب Muhammad Tahir (741682)

"…Furthermore, Trolox-treatment decreased neuroinflammation by inhibiting Toll-like receptor 4 (TLR4), phosphorylated nuclear factor-κB (pNF-κB) and interleukin-1β (IL-1β), and other inflammatory biomarkers of glial cells [ionized calcium-binding adaptor molecule 1 (Iba1) and glial fibrillary acidic protein (GFAP)]. …"

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... حسب Hiroyuki Koami (3878434)

"…We divided the patients into three groups based on the normal CH50 range: Low CH50 (< 25 U/mL; n=168), Normal CH50 (25 ≤, < 48 U/mL; n=1273), and High CH50 (48 ≤ U/mL; n=1285).</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …"

Image3_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG حسب Jacob Raiten (20021262)

"…<p>Stem cell therapy has shown immense promise in treating genetic disorders, particularly muscular diseases like Duchenne muscular dystrophy (DMD). …"

Data Sheet 1_Beta tACS of varying intensities differentially affect resting-state and movement-related sensorimotor power.docx حسب Kym Wansbrough (19711762)

"…<p>Individuals who face difficulties with voluntary movement experience considerable challenges in performing everyday tasks, significantly compromising their sense of autonomy. …"

Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx حسب Safiya Al Yazeedi (22075034)

"…<p>Mechanical strain plays a significant role in lung pathophysiology. …"