يعرض 17,401 - 17,420 نتائج من 20,810 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance p decrease ))~', وقت الاستعلام: 0.55s تنقيح النتائج
  1. 17401

    Table 1_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx حسب Cindy E. Frias (20899853)

    منشور في 2025
    "…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…"
  2. 17402

    Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx حسب Xin Zhou (54275)

    منشور في 2025
    "…Proteomics analysis, histological evaluation, immunohistochemistry, TUNEL staining, immunofluorescence, RT-qPCR, western blot, ELISA, and oxidative stress assays were performed to assess the effects of rutin on ARDS.</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …"
  3. 17403

    Table 3_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx حسب Cindy E. Frias (20899853)

    منشور في 2025
    "…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…"
  4. 17404

    Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx حسب Xin Zhou (54275)

    منشور في 2025
    "…Proteomics analysis, histological evaluation, immunohistochemistry, TUNEL staining, immunofluorescence, RT-qPCR, western blot, ELISA, and oxidative stress assays were performed to assess the effects of rutin on ARDS.</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …"
  5. 17405

    Data Sheet 1_Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles for in vitro toxicity testing of oral tobacco products.docx حسب Xuefei Cao (1700068)

    منشور في 2025
    "…In the organotypic tissue models, both AS and CAS reduced IL-6 secretion without significantly affecting IL-8 levels.</p>Conclusion<p>These findings emphasize the importance of evaluating additional biological responses alongside cytotoxicity in vehicle control studies. …"
  6. 17406

    Data Sheet 1_IL-10 to lymphocyte ratio (ILR) and lactate in the prognosis prediction and risk stratification of sepsis: a pilot study.docx حسب Yuan Yan (1501603)

    منشور في 2025
    "…Kaplan–Meier analysis confirmed significant survival differences (p < 0.001), with Level I demonstrating the worst prognosis.…"
  7. 17407

    Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx حسب Hailan Yan (18174379)

    منشور في 2025
    "…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. …"
  8. 17408

    Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip حسب Shuxian Pan (8868356)

    منشور في 2025
    "…Effective control of viral load through antiviral therapy significantly mitigates the occurrence of irAEs.</p>Conclusion<p>ICIs show therapeutic potential in the treatment of HBV-HCC. …"
  9. 17409

    Table_1_Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.DOCX حسب Jie Zhou (28945)

    منشور في 2024
    "…Furthermore, this combined effect was consistent across all subgroups, and no significant interaction was found (p > 0.05 for interaction).…"
  10. 17410

    Supplementary file 1_Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area.doc حسب Jianhua Li (36075)

    منشور في 2025
    "…Results showed that (1) Compared to R0, the R10 treatment resulted in significant increases in soil organic matter (SOM), total nitrogen (TN), available phosphorus (AP), and available potassium (AK) by 2.1-fold, 1.3-fold, 1.5-fold, and 0.4-fold, and also in activities of β-glucosidase (BG), N-acetyl-β-glucosaminidase (NAG), and leucine aminopeptidase (LAP), by 17-fold, 8.7-fold, and 1.8-fold, respectively (p < 0.05). (2) Rising bacterial diversity (Shannon, Chao1) over time, contrasting with fungal diversity that declined initially before recovering. (3) As the reclamation progressed, the network complexity was increased for both bacteria and fungi, improving stability. …"
  11. 17411

    Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways حسب Lateef Sulaimon (21706283)

    منشور في 2025
    "…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …"
  12. 17412

    Table 2_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

    منشور في 2025
    "…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"
  13. 17413

    Table 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

    منشور في 2025
    "…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"
  14. 17414

    Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx حسب Yihan Sun (3432287)

    منشور في 2025
    "…XBJ also markedly decreased systemic inflammatory biomarkers, including C-reactive protein (CRP; SMD = −1.34), tumour necrosis factor-alpha (TNF-α; SMD = −0.98), and interleukin-6 (IL-6; SMD = −0.98) (all p < 0.01). …"
  15. 17415

    Data Sheet 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.pdf حسب Rui Jiang (264894)

    منشور في 2025
    "…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"
  16. 17416

    Image 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif حسب Felicia Menicucci (7495508)

    منشور في 2025
    "…The leaf polyphenols were characterized and quantified by HPLC-DAD-Q-ToF analysis, the leaf chlorophyll content was measured using a handheld optical analyzer and the photosystem II efficiency was assessed with a porometer-fluorometer.</p>Results<p>The PS II efficiency decreased in response to red LEDs treatment only. …"
  17. 17417

    Table 4_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  18. 17418

    Table 6_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  19. 17419

    Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

    منشور في 2025
    "…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"
  20. 17420

    Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"