Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc حسب Zhenghao Wu (9732511)

"…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …"

Lesioning silent neurons reveals functional role. حسب Thomas S. Wierda (22404198)

"…Mixed-selective neurons, however, lead to a decreased accuracy when lesioned.</p> <p>(TIFF)</p>…"

Table 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc حسب Yaojin Sun (21692411)

"…Bleeding frequency was also recorded.</p>Results<p>Post-treatment, median HEAD-US-C scores decreased from 5.00 to 1.00 (P < 0.001), and HJHS 2.1 scores decreased from 9.00 to 2.00 (P < 0.001). …"

Data Sheet 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc حسب Yaojin Sun (21692411)

"…Bleeding frequency was also recorded.</p>Results<p>Post-treatment, median HEAD-US-C scores decreased from 5.00 to 1.00 (P < 0.001), and HJHS 2.1 scores decreased from 9.00 to 2.00 (P < 0.001). …"

Protective role of <i>N</i>-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway حسب Jianxin Wang (35827)

"…Furthermore, cell viability was found to be significantly enhanced when compared with the controls (<i>p</i> < 0.05). …"

Data Sheet 1_Sustainable remediation of heavy metal contaminated soil through phytostabilization with the in-situ immobilization by mercapto-based palygorskite.docx حسب Hongjie Kuang (22489438)

"…The results showed that soil pH did not vary under the application of MPAL but decreased during the cultivation of C. zizanioides. …"

Supplementary file 1_The bridge between anxiety and insomnia symptoms among Chinese adults before and after SARS-CoV-2 vaccination: a network analysis.doc حسب Yan Liu (25061)

"…The numbers of participants differed much in the two groups.</p>Conclusions<p>The proportion of participants experiencing anxiety and insomnia decreased significantly after SARS-CoV-2 vaccination. …"

Data Sheet 1_NLRP3 regulates epithelial barrier integrity and protects from airway hyperresponsiveness in experimental allergic asthma.pdf حسب Stephanie DeStefano (15457187)

"…</p>Results<p>In comparison to WT mice, NLRP3^-/- mice exhibited significantly enhanced AHR and mucus production, while eosinophilic airway inflammation was comparable. …"

Image 1_The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury.tif حسب Xuexue Cui (11574637)

"…In the RPE/choroid, the abundance of Actinomyces and Roseburia decreased, and the abundance of Lactobacillus increased significantly after laser injury. …"

Data Sheet 1_Unlocking the adaptation mechanisms of the oleaginous microalga Scenedesmus sp. BHU1 under elevated salt stress: a physiochemical, lipidomics and transcriptomics appro... حسب Rahul Prasad Singh (20283954)

"…<p>Microalgae are vital for their photosynthetic abilities, contributing significantly to global oxygen production, serving as a key trophic level in aquatic ecosystems, aiding in biofuel production, assisting in wastewater treatment, and facilitating the synthesis of valuable biochemicals. …"

Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx حسب Tianyao Li (7388201)

"…Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects.…"

Table 1_Altered Th17/Treg balance and therapeutic targeting of RORγ in primary focal hyperhidrosis.docx حسب Min Lin (17652)

"…Background<p>Primary focal hyperhidrosis (PFH) significantly impacts patients’ physical and mental health, yet its underlying mechanisms remain unclear.…"

Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx حسب Jennifer J. Barb (9153014)

"…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …"

Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv حسب Jennifer J. Barb (9153014)

"…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …"

Supplementary Material for: Exploring the ability of novel choroidal biomarkers in predicting treatment outcomes of polypoidal choroidal vasculopathy حسب Zhang Y. (2828780)

"…Results: A higher CVI at baseline was the only factor that correlated with the poor response after 3-monthly injections of anti-VEGF (P=0.038). The greater change of central macular thickness (CMT) was significantly correlated with increased CMT (P=0.030), decreased CT (P=0.042) and decreased CVI (p=0.038) at baseline. …"

Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx حسب Ling Li (38566)

"…RNA-seq analysis was performed to study transcriptional changes in these cells.</p>Results<p>We found that bryostatin-1 improved the expansion and decreased PD-1 expression of HIV-specific CD8+ T cells. …"

Image 3_VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae.jpeg حسب Stephen Mwangi Kamau (20576060)

"…</p>Results and discussion<p>The VdPAT1 deletion mutants displayed reduced colony growth, melanin production, spore yield and germination rate, showed abnormal mycelial branching and decreased ability of mycelial penetration and utilization of nutrients (carbon, amino acids and vitamin), leading to a lower pathogenicity. …"

Image 2_Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone.jpeg حسب Zetong Zheng (22069658)

"…H89 (a PKA inhibitor) or PD98059 (an ERK1/2 signaling inhibitor) was applied in the presence of LH to evaluate crosstalk between the Gn/cAMP and MAPK cascades.</p>Results<p>AQP2 levels in LGCs increased with follicle enlargement after luteinization but decreased as follicles progressed from primordial to antral stages. …"

Data Sheet 5_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Table 1_VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae.xlsx حسب Stephen Mwangi Kamau (20576060)

"…</p>Results and discussion<p>The VdPAT1 deletion mutants displayed reduced colony growth, melanin production, spore yield and germination rate, showed abnormal mycelial branching and decreased ability of mycelial penetration and utilization of nutrients (carbon, amino acids and vitamin), leading to a lower pathogenicity. …"