Table 1_Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis.docx حسب Hongmei Zhao (250090)

"…</p>Results<p>In vivo findings indicated that, in comparison to CBX group (Control group without antibiotic treatment), NAFLD/CBX group (NAFLD group without antibiotic administration) and NAFLD/ABX group (NAFLD group with antibiotic administration) exhibited increased liver-to-body weight ratio, higher lipid droplet accumulation, aggravated liver histopathological damage, and elevated levels of AST (Aspartate Aminotransferase), ALT (Alanine Aminotransferase), TC (Total Cholesterol), TG (Triglycerides), LDL-C (Low-Density Lipoprotein Cholesterol), IL-6 (Interleukin-6), TNF-α (Tumor Necrosis Factor-alpha), IL-1β (Interleukin-1 beta), and NLRP3-related molecules, while HDL-C (High-Density Lipoprotein Cholesterol) levels significantly decreased. Intervention with Bifidobacterium significantly reversed these adverse changes. …"

Data Sheet 1_Machine learning assisted breathomic approach for early-stage thoracic cancer detection.docx حسب Zhenguang Chen (518931)

"…Additionally, in a cohort of 58 cancer patients, model-predicted risk significantly decreased post-surgery (p < 0.01), indicating a strong correlation with disease burden reduction.…"

Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx حسب Wenjia Ge (22687361)

"…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…"

Image 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.tif حسب Haipeng Zhang (3413288)

"…NDEGs were significantly enriched in immune regulation and leukocyte apoptosis (GO) and NETs formation pathway (KEGG). …"

Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx حسب Haipeng Zhang (3413288)

"…NDEGs were significantly enriched in immune regulation and leukocyte apoptosis (GO) and NETs formation pathway (KEGG). …"

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip حسب Erli Wu (17785482)

"…Further assessment demonstrated significantly elevated PANoptosis activity in HGFs from PD compared to controls, which was validated by tissue-level immunofluorescence staining. …"

Data Sheet 1_Development and validation of a sliding type continuous passive motion automation device for evaluation and rehabilitation of frozen shoulder: a pilot study.pdf حسب Jewoo Lee (22028855)

"…Passive stiffness in the intervention group significantly decreased in abduction (p = 0.010) and external rotation (p < 0.001). …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Data Sheet 1_GBD: incidence rates and prevalence of anxiety disorders, depression and schizophrenia in countries with different SDI levels, 1990–2021.pdf حسب Jueqi Wang (21376073)

"…</p>Results<p>In countries with different SDI levels, the age-standardized average annual percentage change (AAPC) in the incidence of anxiety were all shown to be increasing, and there were large gender differences between the different SDI levels, with a maximum of 0.97 (0.76–1.18) for females in countries with a high SDI level, Age-standardized more rates per 100,000 people in high SDI countries, from 658.87 in 1990 to 841.56 in 2021, and the largest gender differences in countries with a low to moderate SDI level, with AAPCs for males and females of 0.04 (0.04–0.05), 0.86 (0.63–1.09); for depression, only the countries with medium-high SDI levels were statistically significant compared to the countries with medium-low SDI levels, with AAPCs of 0.05 (0.04–0.07), 0.04 (0.04–0.05); for schizophrenia in addition to the AAPCs of the countries with medium-high SDI levels showed an increase of 0.16 (0.13–0.18); the rest decreased.…"

Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx حسب Li Zhang (8200)

"…</p>Results<p>In addition to significant within group improvements over time for both groups, OLS linear regression with Full Information Likelihood Estimation revealed a statistically significant between group treatment effects across outcome domains, including psychological distress, b = 22.60, p < 0.001, g = 11.34, somatic symptoms, b = 6.79, p < 0.001, g = 6.56, depressive symptoms, b = 8.15, p < 0.001, g = 8.19, and anxiety symptoms, b = 7.69, p < 0.001, g = 8.23.…"

DataSheet1_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip حسب Timothy G. Wanninger (20296455)

"…Hepatic macrophages also showed differential expression of gene sets related to monocyte/macrophage differentiation, antigen presentation, and T cell activation, which were associated with decreased MHC-II allele expression. …"

DataSheet2_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip حسب Timothy G. Wanninger (20296455)

"…Hepatic macrophages also showed differential expression of gene sets related to monocyte/macrophage differentiation, antigen presentation, and T cell activation, which were associated with decreased MHC-II allele expression. …"

<b>Canagliflozin-induced adaptive metabolism in bone</b> حسب Sher Bahadur Poudel (20686192)

"…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …"

Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale حسب figshare admin karger (2628495)

"…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …"

Caffeine induces proteome-wide changes in a Rob-dependent manner. حسب Christoph Binsfeld (21763112)

"…The double-sided Fisher’s exact test p-value for enrichment of OMPs among significantly decreased proteins is shown. (D) Comparison of proteome changes between wild type and Δ<i>rob</i> upon caffeine treatment. …"

Data Sheet 1_Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study.docx حسب Dehao Chen (4966207)

"…Prelacteal feeding significantly increased Campylobacter load in the first month of life. …"

Image 1_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png حسب Eyad Talal Attar (22124251)

"…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …"

Image 8_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png حسب Eyad Talal Attar (22124251)

"…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …"

Table 3_Comparative performance evaluation of large language models in answering esophageal cancer-related questions: a multi-model assessment study.xlsx حسب Zijie He (8194938)

"…Retesting showed improvements in overall quality, yet some responses showed decreased completeness and relevance.</p>Conclusion<p>Large language models have considerable potential in answering questions about esophageal cancer, with significant differences in completeness. …"

Image 6_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png حسب Eyad Talal Attar (22124251)

"…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …"