Data Sheet 1_Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators.pdf by Michael Hecker (51971)

“…In contrast, MS patients who underwent apheresis (n_max=27) showed strong immunoglobulin reduction rates, especially for IgG, and decreased antibody reactivities against all tested peptides. …”

Influence of Kar4 deletion on low affinity PRE sites. by Sandrine Pinheiro (21553774)

“…The F indicates that the total fraction of expressing cells is significantly lower (t-test: p-val < 0.05) than the expression from the promoter with two consensus PRE sites. …”

Phage–host adsorption results. by Rokaiya Nurani Shatadru (22656316)

“…Bolded numbers show significant decrease in free phage over time (<i>t</i> test).…”

No effect of PTL on pure primary mouse motor neuron cultures. by Nadine Thau-Habermann (457942)

“…<p>MEA measurements showed that there were no significant differences between the individual wells of plated motor neurons before treatment After 24 and 48 hours, only the LPS+PTL 5 µ M group showed a significant decrease in resistance (A) and in firing rate (B), while all other conditions showed no significant differences between each other. …”

Additional file 4 of Sirtuin1 mitigates hypoxia-induced cardiomyocyte apoptosis in myocardial infarction via PHD3/HIF-1α by Yafen Chen (330564)

“…Statistical analysis using the Log-rank test revealed no significant difference in survival rates between the two groups. …”

Data Sheet 2_An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults.pdf by Luisa Knopf (22518134)

“…</p>Results<p>There was no significant interaction involving time point (laboratory vs. at home) and age group. …”

Data Sheet 1_An intricate relationship: stress markers and associative memory in a laboratory experiment in older adults.pdf by Luisa Knopf (22518134)

“…</p>Results<p>There was no significant interaction involving time point (laboratory vs. at home) and age group. …”

VCC-induced pro-inflammatory responses in DCs are TLR1-dependent but not TLR2-dependent. by Shraddha Gandhi (21001590)

“…Data shown here are the averages ± SDs from three to four independent experiments. ns, non-significant; p > 0.05; one-way ANOVA with Tukey’s multiple comparison test. …”

Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Network effects of DLPFC-tDCS protocols with different stimulation duration. by Yanqing Dong (8829548)

“…Statistical comparisons were made between the tDCS protocol and without-tDCS using a paired-samples t-test (<i>p</i> < 0.05). Only nodes with significant differences (paired-samples t-test) are colored, while the remaining nodes are white. …”

(A) Example of a hypnogram for the same dog under control and trazodone conditions. by Magaly Catanzariti (20865500)

“…Blue arrows indicate a significant decrease, and red arrows an increase in transition probability under trazodone. …”

Drugs causing prostate-specific antigen changes: the food and drug administration adverse event reporting system combined with Mendelian randomization analysis by Wei Zhang (405)

“…Heterogeneity test, horizontal pleiotropy test and leave-one-out Analysis verified the stability of the results. …”

Image1_RETRACTED: miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats.tif by Yang Yang (45629)

“…Here, a chronic unpredicted mild stress (CUMS) depression model in rats was established, and then raphe nuclei miR-16 and intragastric Fluoxetine injections were administered for a duration of 3 weeks. An open field test and sucrose preference quantification displayed a significant decrease in the CUMS groups when compare to the control groups, however these changes were attenuated by both miR-16 and Fluoxetine treatments. …”

Hsp90 mutation does not impact TDP-43 protein levels at the permissive temperature, 16°C. by Laura Garcia-Toscano (20477540)

“…Error bars represent SEM: N = 4. Statistical significance as determined using unpaired t-test. (ns = not signficant) <b>D.…”

Figure 4 from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models by Isabel Quiros-Gonzalez (14952835)

“…<b>A</b> and <b>B,</b> Oxygenation (SO₂^MSOT) and normalized hemoglobin content (THb) increase from enrollment (noted as “pre”) to endpoint of tumor excision (noted as “post”) in the Ctrl group (<b>A</b>), while in the Bev-NR group (<b>B</b>), SO₂^MSOT increases concurrently with a decrease in normalized THb. <b>C,</b> Conversely, the Bev-R group trend toward a significant decrease in SO₂^MSOT, with no significant change in normalized THb observed. …”

Table 1_Effects of the efficacy of the Yi Shen Tiao Gan formula on aromatase inhibitor associated musculoskeletal syndrome: a randomized controlled trial.xlsx by Yan Zhang (8098)

“…After applying Bonferroni correction for multiple testing, these associations did not reach statistical significance. …”

Figure 1 from Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival by Fabian R. Villagomez (17802976)

“…<b>D,</b> Model illustrating that claudin-4 overexpression reduces the proportion of tumor cells in the S-phase of the cell cycle, whereas its downregulation results in an accumulation of cells in the G2–M phase and a decrease in the G0–G1 phase. (four independent experiments, three independent experiments for OVCAR3 at 96 hours; two-tailed unpaired <i>t</i> test; significance <i>P</i> < 0.05). …”

TLR4 is involved in the VCC-induced activation of BMDCs. by Shraddha Gandhi (21001590)

“…Data shown here are the averages ± SDs from three independent experiments. ns, non-significant; *, p < 0.05; ***, p < 0.001; one-way ANOVA with Tukey’s multiple comparison test. …”

Table 1_Efgartigimod combined with steroids as a fast-acting therapy for anti-SRP immune-mediated necrotizing myopathy.doc by Qiqi Peng (6560057)

“…Evidently, these three patients demonstrated significant improvement in muscle strength and decrease of serum CK levels after efgartigimod treatment. …”