يعرض 4,521 - 4,540 نتائج من 4,694 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance test decrease ))~', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 4521

    Table 1_CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.docx حسب Liubing Hou (10888140)

    منشور في 2025
    "…Background<p>Radioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. CD9, as a crucial membrane regulatory protein, exhibits dual regulatory roles in various cancers, yet its precise mechanism in ESCC radioresistance remains unclear. …"
  2. 4522

    Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... حسب Wenjing He (4278625)

    منشور في 2025
    "…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …"
  3. 4523

    Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  4. 4524

    Data Sheet 1_Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence.docx حسب Omkar B. Ijare (22274167)

    منشور في 2025
    "…The CE-to-cholesterol ratio of 0.44 in the recurrent tumor suggests significant cholesterol esterification during malignant progression.…"
  5. 4525

    Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  6. 4526

    Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  7. 4527

    Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  8. 4528

    Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b> حسب Lucy Aliette Janet Mirabib Ame De Guilhem De Lataillade (11192853)

    منشور في 2025
    "…</p><p dir="ltr">Brief project description</p><p dir="ltr">Mosquito-borne diseases kill more humans than humans do and have done so for a long time. The most significant diseases transmitted by mosquitoes currently lack effective vaccines, and existing control methods face increasing resistance. …"
  9. 4529

    Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... حسب Wu Chen (569414)

    منشور في 2025
    "…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…"
  10. 4530

    Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls حسب Yuan Deng (177795)

    منشور في 2025
    "…Background<p>Diabetic nephropathy (DN) is a major complication of diabetes, contributing significantly to end - stage renal disease. Irisin, an exercise - induced myokine, has been linked to metabolic disorders, but its relationship with DN remains unclear. …"
  11. 4531

    DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx حسب Rocío Rubio (513839)

    منشور في 2025
    "…None of the newborns tested positive for rRT-PCR. SARS-CoV-2 infected mothers had increased levels of virus-specific antibodies and several cytokines. …"
  12. 4532

    DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx حسب Mehri Hajiaghayi (19822665)

    منشور في 2024
    "…Nebivolol-treated β<sub>2</sub>-knockout memory Th cells showed significant inhibition of β<sub>2</sub>-AR-mediated signaling, evidenced by the absence of IL-17A suppression compared to controls. …"
  13. 4533

    USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology. حسب Amy N. Nelson (21763146)

    منشور في 2025
    "…Statistical analysis was performed using one sample t tests comparing USUV RNA detected in samples to the limit of detection. …"
  14. 4534

    Data_Sheet_1_RETRACTED: The Variation of Nasal Microbiota Caused by Low Levels of Gaseous Ammonia Exposure in Growing Pigs.pdf حسب Tongxin Wang (2524945)

    منشور في 2025
    "…Four microbial genera (Pseudomonas, Lactobacillus, Prevotella, and Bacteroides) were significantly decreased at 25 ppm, while only two genera (Moraxella and Streptococcus) were increased at 25 ppm. …"
  15. 4535

    Data Sheet 1_Dynamics of soil nutrients and biological activities along an infection chronosequence of pine wilt disease in subtropical Masson pine forests.docx حسب Xueyu Song (3600464)

    منشور في 2025
    "…The results revealed that soil non-capillary porosity, clay, microbial biomass carbon and microbial biomass nitrogen decreased significantly in 6 years forests. Available potassium consistently decreased with longer invasion periods, while soil polyphenol oxidase, leucine amino peptidase, and available phosphorous peaked in 6 years forests and then declined over time. …"
  16. 4536

    Figure 6 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma حسب Gwendolyn M. Cramer (16964052)

    منشور في 2025
    "…<p>PD-1 blockade significantly decreases tumor growth rates in combination with TI/PDT. αPD-1 initiated 1 hour after PDT and continuing 2× weekly for 3 weeks did not significantly alter tumor growth rates. …"
  17. 4537

    Supplementary file 1_Divergent germination strategies of Phragmites australis seeds for tidal flat gradient adaptation and the implications for coastal wetland restoration.docx حسب Peng Jia (194819)

    منشور في 2025
    "…With the increase in salinity, the germination speeds of different tidal flats slowed down, and the germination index decreased. 4°C storage significantly enhanced the seed germination rate and germination potential of the low-tidal flat population (L) relative to room-temperature storage. …"
  18. 4538

    Spearman Correlation Coefficient results under feature perturbation. حسب Yusuke Suita (14381481)

    منشور في 2025
    "…Each epigenetic signal was perturbed separately when the model was trained with GSC1 and tested with GSC2. The model performance when H3K27Ac signals were perturbed was significantly decreased in comparison to the other signals.…"
  19. 4539

    Image 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.jpeg حسب Hana Kahleova (618836)

    منشور في 2025
    "…Three-day dietary records were analyzed, and Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) were calculated as markers of dietary acid load, and their relationship was tested with changes in body weight.</p>Results<p>Compared with no change on the Mediterranean diet, PRAL and NEAP significantly decreased on the vegan diet; effect sizes: −25.8 (95% CI −34.1 to −17.5); p < 0.001; and −27.1 (95% CI −35.4 to −18.7); p < 0.001, respectively. …"
  20. 4540

    Table 1_Dietary acid load on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.docx حسب Hana Kahleova (618836)

    منشور في 2025
    "…Three-day dietary records were analyzed, and Potential Renal Acid Load (PRAL) and Net Endogenous Acid Production (NEAP) were calculated as markers of dietary acid load, and their relationship was tested with changes in body weight.</p>Results<p>Compared with no change on the Mediterranean diet, PRAL and NEAP significantly decreased on the vegan diet; effect sizes: −25.8 (95% CI −34.1 to −17.5); p < 0.001; and −27.1 (95% CI −35.4 to −18.7); p < 0.001, respectively. …"