يعرض 841 - 860 نتائج من 4,694 نتيجة بحث عن '(( significant decrease decrease ) OR ( significance test decrease ))~', وقت الاستعلام: 0.39s تنقيح النتائج
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  2. 842

    Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …"
  3. 843

    PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …"
  4. 844

    Juvenile demyelination impairs the maturation of PV interneurons in the PFC. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …"
  5. 845
  6. 846

    Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Note that in cuprizone mice there was no difference (<i>group x current two-way repeated measures: n = 19,19,18,18 cells from 9−8 mice per group: F(39,856) = 1.671, p = 0.0068, post-hoc LSD test: *p < 0.05</i>). <b>F</b>. Summary data of the maximum firing frequency per group revealing a decrease in the maximum firing frequency in PV interneurons that do not have autapses (<i>t test of control with vs. without autapse; n = 19 cells from 9 mice per group, *p < 0.01; t test of cuprizone with vs. without autapse; n = 17 cells from 8 mice per group, p = 0.0722</i>). …"
  7. 847

    Comparison between juvenile and adult demyelination. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Juvenile demyelination leads to impairment in PV interneuron maturation whereas adult demyelination induces a decrease in the excitability of PV interneurons. Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …"
  8. 848

    Juvenile demyelination induces a loss of functional autapses. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …"
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  12. 852
  13. 853

    AUT00201 (1 µM) can rescue AP width in cuprizone mice. حسب Sara Hijazi (21656615)

    منشور في 2025
    "…Post-hoc LSD test: *p < 0.05, n.s. p = 0.0957</i>). <b>B</b>. …"
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