Image 1_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.tif by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Data Sheet 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.pdf by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Image 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.tif by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Table 3_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

DataSheet1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.PDF by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

Table 2_Antifungal activity of cinnamaldehyde against Aspergillus fumigatus involves disruption of the TCA cycle and protein metabolism.xlsx by Fang Li (41162)

“…Following treatment with CA, the protein expression of the putative translation initiation factor eIF4E3 (AFUB_051690), the putative leucyl-tRNA synthetase LeuRS (AFUB_093380), prolyl-tRNA synthetase ProRS (AFUB_010170) and the putative peptidyl-tRNA hydrolase Pth1 (AFUB_053480) exhibited a significant decrease. Moreover, deletion of pth1 resulted in a severe growth defect and hypersensitivity to CA, as evidenced by complete growth arrest at 30 and 45 μg/mL CA. …”

Table1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.XLSX by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

<b>Three-year follow-up after antiviral treatment in new-onset type 1 diabetes. Results from the Diabetes Virus Detection and Intervention trial.</b> by Ida M. Mynarek (20479470)

“…There was no statistically significant difference between the groups. The groups were also comparable with regard to secondary endpoints.…”

Table 1_2,4-Di-tert-butylphenol from Endophytic Fungi Fusarium oxysporum attenuates the growth of multidrug-resistant pathogens.docx by Ranjitha Dhevi V. Sundar (21515288)

“…The results highlighted that compound DTB from F. oxysporum showed significant pharmaceutical potential, indicating its suitability as a lead molecule. …”

Figure 6 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer by Jennifer M. Finan (14951382)

“…<i>P</i> values were calculated using an unpaired two-tailed Student <i>t</i> test. *, <i>P</i> < 0.05; **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001; ns, not significant.…”

Image_1_Oat polar lipids and sunflower lecithin similarly improve cardiometabolic risk markers and appetite controlling hormone responses after breakfast and a subsequent lunch. A... by Mohammad Mukul Hossain (20128593)

“…Poor dietary choices significantly contribute to this increase and prevention measures are urgently needed. …”

VCC induces activation of neutrophils through TLR1/4/MyD88. by Shraddha Gandhi (21001590)

“…Data shown here are the averages ± SDs from the four independent experiments. ns, non-significant; **, p < 0.01; one-way ANOVA with Dunnett’s multiple comparison test. …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>O</b>, <b>P</b>) Cell proliferation assay confirms an increase in cell proliferation of BT-474_ZFX^OE cells (mean ± SEM, <i>n</i> = 5) (O), whereas BT-474_ZFX^SL cells (mean ± SEM, <i>n</i> = 3) show decreased cell proliferation (P). (<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX^OE (mean ± SEM, <i>n</i> = 5) than BT-474_VECT^OE tumors. …”

Data Sheet 2_Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.pdf by Robert B. Rebhun (8479020)

“…Cytotoxicity assays of PBMCs showed significant decreases after both surgery and chemotherapy with an overall decrease from the start to end of therapy (-18.2 ± 16.1%, P<0.001). …”

Data Sheet 1_Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.pdf by Robert B. Rebhun (8479020)

“…Cytotoxicity assays of PBMCs showed significant decreases after both surgery and chemotherapy with an overall decrease from the start to end of therapy (-18.2 ± 16.1%, P<0.001). …”

Basal HLH-30 activity is not accompanied by enriched nuclear localization and declines during neuronal aging. by Ruiling Zhong (22339779)

“…**<i>P</i> < 0.01, ns: not significant, One-way ANOVA with Tukey post-test [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002957#pbio.3002957.ref062" target="_blank">62</a>]. …”

Data Sheet 1_Impact of zero-markup consumable policy and national procurement of coronary stents on hospitalization expenses: an interrupted time series analysis.pdf by Shao-long Wu (1948273)

“…Background<p>After the successful reforms of drug pricing, China has implemented two significant reforms to reduce medical consumables expenses: the elimination of markup on prices (zero-markup policy) and the implementation of centralized procurement of high-value medical consumables (national procurement policy). …”

Dorsal and chinmo mutually influence each other’s expression, driving tumor growth while inhibiting differentiation. by Caroline Dillard (15381444)

“…Chinmo (magenta) upregulation upon Dorsal overexpression in clones is visible in the insets bellow each image. Statistical significance was determined with an Unpaired <i>t</i> test with Welch’s correction. …”

Table 3_Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster.xlsx by Florance Parweez (22534262)

“…The diverse health benefits of spermidine supplementation, often at doses that do not significantly alter spermidine levels of target organs, suggests that exogenous spermidine may have a common site of action, the gastrointestinal (GI) tract.…”

Image 3_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”