<b>Cannabinoid Receptor 2 Agonism Demonstrates Therapeutic </b><b>Potential in Experimental Models of Relevance to Diabetic Retinopathy</b> by Cayla D. Ontko (21434062)

“…<i>In vivo</i>, both intraocular and systemic HU-308 administration significantly decreased retinal leukostasis in cytokine-induced inflammation and STZ-induced diabetes. …”

Data Sheet 1_Treatment of bacterial biothreat agents with a novel purified bioactive lactoferrin affects both growth and biofilm formation.docx by Christian Xander (9120108)

“…Here, we show that Lactea Lf can significantly inhibit biofilm and decrease the overall growth in a dose dependent manner for all Burkholderia species tested. …”

Table 1_Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster.xlsx by Florance Parweez (22534262)

“…The diverse health benefits of spermidine supplementation, often at doses that do not significantly alter spermidine levels of target organs, suggests that exogenous spermidine may have a common site of action, the gastrointestinal (GI) tract.…”

Table 2_Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster.xlsx by Florance Parweez (22534262)

“…The diverse health benefits of spermidine supplementation, often at doses that do not significantly alter spermidine levels of target organs, suggests that exogenous spermidine may have a common site of action, the gastrointestinal (GI) tract.…”

Image 2_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”

Image 1_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”

Table 2_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.docx by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”

Table 1_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.docx by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... by Aya Miyagawa-Hayashino (386487)

“…The changes in protein levels of RhoA and ROCK1 were not significant. *<i>P</i><0.05 by one-way ANOVA, Dunnett’s multiple comparison test compared with DMSO control in (A) and (B). …”

Data Sheet 1_Aronia melanocarpa L. fruit peels show anti-cancer effects in preclinical models of breast carcinoma: The perspectives in the chemoprevention and therapy modulation.do... by Dana Dvorska (19809111)

“…In the same tumors, we noted a significant dose-dependent decrease in the mitotic activity index compared to the control. …”

Glia-targeted 5-HT_2A receptor expression in adults reopens experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…There is a significant decrease in the Or42a OSN innervation volume with glial-targeted <i>Gal80</i>^<i>ts</i><i>-5-HT</i>_<i>2A</i><i>R</i> OE at 28°C (<i>n</i> = 20/condition, <i>p</i> = 1.00 × 10⁻¹⁵). …”

XRD spectra of HPC at 28, 56, and 90 days. by Fadi Althoey (13040091)

“…Activated WSA-RA concrete showed significantly improved early strength. The mixture with 30% RA, 40% WSA, WTSFs, and activator exhibited the highest strength at 90 days. …”

Mix details of samples (kg/m³). by Fadi Althoey (13040091)

“…Activated WSA-RA concrete showed significantly improved early strength. The mixture with 30% RA, 40% WSA, WTSFs, and activator exhibited the highest strength at 90 days. …”

Data Sheet 1_Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish.docx by Ying–Ying Zhang (21776942)

“…Post-exposure assays (mirror test and dyadic interaction) revealed that Mix significantly reduced the frequency of approaching mirror, the attack mirror duration, and the frequency of chasing un-exposed fish, indicating a decrease in aggressive behaviour in Mix-fish. …”

Supplementary file 1_Protective effects and mechanism of resveratrol in animal models of pulmonary fibrosis: a preclinical systematic review and meta-analysis.docx by Yajie Yin (10115902)

“…Improved fibrosis: significant reduction in pulmonary fibrosis score (SMD = −2.30, 95% CI [−2.80, −1.79], p < 0.00001, I² = 76%) and decreased Hyp content (SMD = −2.16, 95% CI [−2.69, −1.63], p < 0.00001, I² = 85%); 2. …”

VCC monomer and pre-formed oligomer induce pro-inflammatory responses in the BMDCs. by Shraddha Gandhi (21001590)

“…. **, p < 0.01; ***, p < 0.001; one-way ANOVA with Dunnett’s multiple comparison test. (B) Dose-dependent decrease in the viability of BMDCs upon treatment with VCC monomer (left panel), and pre-formed VCC oligomer (right panel). …”

Table 1_Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat.docx by Shellye González-González (20517563)

“…In contrast, DLAN male offspring exhibited a significant decrease in social play behavior compared to LD animals, which was associated with higher numbers of microglia in the NAc that had more ramified morphology. …”

A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease by Akanksha Chhabra (71080)

“…Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). …”

Table 1_Evaluation of environmental risk factors associated with survival of generic E. coli in organic integrated crop-livestock systems in California and Minnesota.docx by Annette Kenney (14843218)

“…Concentrations (Most Probable Number/100 g) of gEc in grazed soil returned to levels comparable to non-grazed or fallow treatments within 87–147 days post-graze (DPG) in both years, with a significant decrease predicted after 32 DPG. Interestingly, non-O157 STEC was detected in soil even after concentrations of gEc declined 115–147 DPG.…”

Co-immunoprecipitation and BiFC experiments related to Abd-B and Exd interaction. by Jesús R. Curt (20553231)

“…Protein present in the co-IPs is indicated above the gels. There is a significant decrease in the amount of the Abd-B^W protein captured on the resin when compared to the Abd-B wildtype protein (24%), while Exd remains almost unchanged (2%). …”