Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”

Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx by Abraham Alí-Munive (21347201)

“…FEV₁pp showed higher but not significant values from the 2–4-month period, with a median change of 12.5% (IQR: 0.3, 21.5). …”

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... by Deliang Kong (382201)

“…The trend in PTB-DM incidence was analyzed using the Joinpoint regression model, and population and clinical characteristics of patients were described using frequencies (n) and percentages. Chi-squared test and Fisher’s exact tests was used to compare groups, and multivariable logistic regression model with stepwise backward elimination based on the Wald test was used to examine risk factors for adverse treatment outcomes.…”

Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls by Yuan Deng (177795)

“…Background<p>Diabetic nephropathy (DN) is a major complication of diabetes, contributing significantly to end - stage renal disease. Irisin, an exercise - induced myokine, has been linked to metabolic disorders, but its relationship with DN remains unclear. …”

Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…<b>A,</b> In subcutaneous AB12 mouse mesothelioma tumors, TI significantly decreased the median tumor growth time to 400 mm³ from 7 days compared with 9 days in untreated TC (<i>P</i> = 0.025). …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…L, Left; LV, left ventricle; n.s., non-significant; R, Right; RV, right ventricle. See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002598#pbio.3002598.s014" target="_blank">S1 Data</a> for the underlying data.…”

Supplementary file 3_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…<b>(B)</b> The fold change of p62 and <b>(C)</b> LC3BI between negative control/cell-only samples and miR-7974-treated samples were statistically significant. GAPDH was used as a reference protein. …”

Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

The role of SLMO in the PSS/PISD pathway. by Siwen Zhao (543384)

“…Mitochondria size was quantified and significant differences were determined using the unpaired <i>t</i> test.…”

Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 1_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 5_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Hippocampal volume changes along the rostrocaudal axis in the COUP-TFI mutant mice. by Ching-San Tseng (6252566)

“…In the rostral sections (1,800–3,000 µm), the Hp area size is significantly smaller in the cKO and larger in the cTG. …”

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. by Andrew B. Harvey (21587431)

“…<b>(H)</b> Quantification of GFP+ fluorescence area, first normalized to DAPI area to account for myocardial area differences, then normalized to control (set to 1.0) for comparison between genotypes (n = 4, Student’s unpaired t-test). <b>(I)</b> Nearest-neighbor analysis reveals a decreased average distance between GFP+ object centroids and their nearest CD109 + neighbor in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG specimens. …”

Ca²⁺ homeostasis and the corpuscles of Stannius regulate sensory gating. by Susannah S. Schloss (21238775)

“…Exposure to media containing low Ca²⁺ (0.02 and 0.001 mM) did not significantly affect whole-body Ca²⁺ levels (<i>n</i> = 3 biological replicates per condition, <i>p</i> = 0.8297, <i>p</i> = 0.093; one-way ANOVA with Dunnett’s multiple comparisons test). …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

“…Black are all detected transcripts belonging to the cholesterol biosynthesis pathway, the significantly [adj. <i>P</i> < 0.05, |log₂ fc| > log₂ (1.5)] modulated ones are indicated with name. …”

DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx by Rocío Rubio (513839)

“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. by Aïssatou Aïcha Sow (20371233)

“…Data are means ± SEM. *** P ≤ 0.001; ** P ≤ 0.01; * P ≤ 0.05; Student’s t-test for each day. (H-I) Treatment of ZIKV-infected fish with 100 μM NITD008 decreased the viral load. …”